Results 101 to 110 of about 381,907 (300)

Distributed and specific encoding of sensory, motor, and decision information in the mouse neocortex during goal-directed behavior

Cell Reports
Summary: Goal-directed behaviors involve coordinated activity in many cortical areas, but whether the encoding of task variables is distributed across areas or is more specifically represented in distinct areas remains unclear.
Anastasiia Oryshchuk, Christos Sourmpis, Julie Weverbergh, Reza Asri, Vahid Esmaeili, Alireza Modirshanechi, Wulfram Gerstner, Carl C.H. Petersen, Sylvain Crochet   +8 more
doaj   +1 more source

Effects on the Motor Cortex in Gamma Rhythm in Terms of Central Pattern Generator

IEEE Access, 2019
The locomotion is one of the basic skills essential for animals' survival. It is a key research field where the locomotion is modulated by the motor cortex.
Qiang Lu, Zhenpeng Ma, Wenfeng Li
doaj   +1 more source

Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease [PDF]

, 2017
Huntington's disease is an autosomal dominant inherited neurodegenerative disease with motor symptoms that are variably co-expressed with mood and cognitive symptoms, and in which variable neuronal degeneration is also observed in the basal ganglia and ...
Faull, Richard L. M., Hogg, Virginia M., Luthi-Carter, Ruth, Nana, Alissa L., Oorschot, Dorothy E., Synek, Beth J., Thu, Doris C. V., Tippett, Lynette J., Waldvogel, Henry J.   +8 more
core  

Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation. [PDF]

, 2016
Using ultra-high field 7 Tesla (7T) functional magnetic resonance imaging (fMRI), we map the cortical and perceptual responses elicited by intraneural microstimulation (INMS) of single mechanoreceptive afferent units in the median nerve, in humans ...
Ackerley, Benjamini, Benjamini, Besle, Bianciardi, Blankenburg, Burton, Burton, Favorov, Ferretti, Francis, Gati, Gelnar, Gescheider, Huang, Hurley, Johansson, Johansson, Kaas, Kampe, Kelly, Klatzky, Landry, Martuzzi, Masamoto, McGlone, Nelson, Ochoa, Overduin, Paul, Penfield, Preusser, Rausell, Reed, Sanchez-Panchuelo, Sanchez-Panchuelo, Servos, Tommerdahl, Torebjörk, Trulsson, Uğurbil, Vallbo, Vallbo, Vallbo, Vickery   +44 more
core   +5 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. [PDF]

, 2006
Motor training can induce profound physiological plasticity within primary motor cortex, including changes in corticospinal output and motor map topography.
Chan, Sheila, Cramer, Steven C, Jimenez, Richard, Kleim, Jeffrey A, Pringle, Erin, Procaccio, Vincent, Schallert, Kellan   +6 more
core  

Effect of transcranial direct current stimulation combined with gait and mobility training on functionality in children with cerebral palsy: study protocol for a double-blind randomized controlled clinical trial [PDF]

, 2013
Background: The project proposes three innovative intervention techniques (treadmill training, mobility training with virtual reality and transcranial direct current stimulation that can be safely administered to children with cerebral palsy.
Collange, Nelci Zanon, Corrêa, João Carlos Ferrari, de Carvalho, Paulo de Tarso Camilo, de Mendonça, Mariana Emerenciano, de Oliveira, Luis Vicente Franco, Duarte, Natália de Almeida Carvalho, Franco, Renata Calhes, Fregni, Felipe, Galli, Manuela, Grecco, Luanda André Collange, Lima, Vânia Lúcia Costa de Carvalho, Oliveira, Claudia Santos, Pasini, Hugo, Sampaio, Luciana Maria Malosá   +13 more
core   +1 more source

Functional MRI Evidence for Motor Cortex Reorganization Adjacent to a Lesion in a Primary Motor Cortex

American Journal of Physical Medicine & Rehabilitation, 2002
The object of this study was to verify motor cortex reorganization in patients with primary motor cortex injury using functional magnetic resonance imaging.Ten control subjects and two patients with primary motor cortex injury, caused by a traumatic brain injury in patient 1 and meningioma in patient 2, were evaluated.
Sung Ho Jang, Bong Soo Han, Yongmin Chang, Woo Mok Byun, Jun Lee, Sang Ho Ahn   +5 more
openaire   +3 more sources

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source