Results 241 to 250 of about 376,168 (350)

Long‐Term Memory Updating Parallels Altered Awake and Sleep Hippocampal Replays

open access: yesAdvanced Science, EarlyView.
This study introduces a behavioral paradigm for memory updating and reveals underlying hippocampal mechanisms. Replays of place cells predict future behavioral choices during behavior and show a bias toward high‐reward locations during non‐rapid eye movement (NREM) sleep, specifically within the memory updating process.
Jifu Tong   +14 more
wiley   +1 more source

Redundant information encoding in primary motor cortex during motor tasks

open access: green, 2011
Kelvin So   +3 more
openalex   +2 more sources

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

open access: yesAdvanced Science, EarlyView.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang   +6 more
wiley   +1 more source

Comparison of Transcranial Direct Current Stimulation of the Primary Motor Cortex and Cerebellum on Static Balance in Older Adults

open access: diamond, 2020
Hamzeh Baharlouei   +6 more
openalex   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

open access: yesAdvanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang   +6 more
wiley   +1 more source

Population coding in primary motor cortex

open access: yes, 2019
The mammalian primary motor cortex (M1) is positioned upstream of spinal motor circuits, and its output drives movement execution. While traditional electrophysiological techniques have developed our understanding of neural coding in motor cortex, they lack the ability to resolve fine-grained spatiotemporal patterns of neuronal ensemble activity. Here,
openaire   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

open access: yesAdvanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie   +5 more
wiley   +1 more source

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