Long‐Term Memory Updating Parallels Altered Awake and Sleep Hippocampal Replays
This study introduces a behavioral paradigm for memory updating and reveals underlying hippocampal mechanisms. Replays of place cells predict future behavioral choices during behavior and show a bias toward high‐reward locations during non‐rapid eye movement (NREM) sleep, specifically within the memory updating process.
Jifu Tong +14 more
wiley +1 more source
Redundant information encoding in primary motor cortex during motor tasks
Kelvin So +3 more
openalex +2 more sources
Modulation of primary motor cortex after experimentally induced and use-dependent plasticity in young and older adults. [PDF]
Cirillo J +5 more
europepmc +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
Effect of transcranial direct current stimulation over the primary motor cortex on short-term balance acquisition in healthy individuals. [PDF]
Tor ÖB +4 more
europepmc +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Population coding in primary motor cortex
The mammalian primary motor cortex (M1) is positioned upstream of spinal motor circuits, and its output drives movement execution. While traditional electrophysiological techniques have developed our understanding of neural coding in motor cortex, they lack the ability to resolve fine-grained spatiotemporal patterns of neuronal ensemble activity. Here,
openaire +1 more source
Dissociable Causal Roles of Dorsolateral Prefrontal Cortex and Primary Motor Cortex over the Course of Motor Skill Development. [PDF]
Nguyen QN, Michon KJ, Vesia M, Lee TG.
europepmc +1 more source
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie +5 more
wiley +1 more source

