Results 31 to 40 of about 3,200 (215)

Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury

Redox Biology, 2021
Motor neuron death is supposed to result in primary motor cortex atrophy after spinal cord injury (SCI), which is relevant to poorer motor recovery for patients with SCI. However, the exact mechanisms of motor neuron death remain elusive.
Zhou Feng, Lingxia Min, Hui Chen, Weiwei Deng, Mingliang Tan, Hongliang Liu, Jingming Hou   +6 more
doaj   +1 more source

Corticostriatal Activity in Primary Motor Cortex of the Macaque [PDF]

The Journal of Neuroscience, 2000
Although input from corticostriatal neurons (CSNs) plays a critical role in basal ganglia functions, little is known about CSN activity during behavior. We compared the properties of antidromically identified CSNs with those of antidromically identified neurons that project via the cerebral peduncle to distant targets.
R S, Turner, M R, DeLong
openaire   +2 more sources

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Patterns of myeloarchitecture in lower limb amputees: an MRI study

Frontiers in Neuroscience, 2015
Functional studies of cortical plasticity in humans suggest that the motor cortex reorganizes when the descending motor output pathway is disrupted as a result of limb amputation.
Eyesha eHashim, Christopher D Rowley, Sharon eGrad, Nicholas A Bock   +3 more
doaj   +1 more source

Different modulation of common motor information in rat primary and secondary motor cortices. [PDF]

PLoS ONE, 2014
Rodents have primary and secondary motor cortices that are involved in the execution of voluntary movements via their direct and parallel projections to the spinal cord.
Akiko Saiki, Rie Kimura, Toshikazu Samura, Yoko Fujiwara-Tsukamoto, Yutaka Sakai, Yoshikazu Isomura   +5 more
doaj   +1 more source

Off-Line Learning and the Primary Motor Cortex [PDF]

The Journal of Neuroscience, 2005
We are all familiar with acquiring skills during practice, but skill can also continue to develop between practice sessions. These “off-line” improvements are frequently supported by sleep, but they can be time dependent when a skill is acquired unintentionally.
Edwin M, Robertson, Daniel Z, Press, Alvaro, Pascual-Leone   +2 more
openaire   +2 more sources

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Prediction of movement intention using connectivity within motor-related network: An electrocorticography study. [PDF]

PLoS ONE, 2018
Most brain-machine interface (BMI) studies have focused only on the active state of which a BMI user performs specific movement tasks. Therefore, models developed for predicting movements were optimized only for the active state.
Byeong Keun Kang, June Sic Kim, Seokyun Ryun, Chun Kee Chung   +3 more
doaj   +1 more source

Pain-motor integration in the primary motor cortex in Parkinson's disease [PDF]

Brain Stimulation, 2017
In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through transcranial magnetic stimulation (TMS), in a laser-paired associative stimulation design (Laser-PAS)
SUPPA, ANTONIO, LEONE, CATERINA, DI STASIO, FLAVIO, MARSILI, LUCA, Di Santo, A, Biasiotta, A, LA CESA, SILVIA, TRUINI, ANDREA, CRUCCU, Giorgio, BERARDELLI, Alfredo   +9 more
openaire   +4 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source