The Calreticulin gene and myeloproliferative neoplasms [PDF]
, 2016 The Philadelphia negative myeloproliferative neoplasms include polycythaemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF).
Clinton, Aoibhinn +1 more
core +1 more source
Cancer Science, EarlyView.This study indicates that SPP1, as an important regulator of tumor progression, is upregulated in various tumors and has been associated with a poor prognosis. SPP1+M2 has a unique spatial location at the forefront of tumor invasion and metastasis, thereby promoting tumor progression. MARCO+M2, which forms a mutually exclusive relationship with SPP1+M2,
Xuan Luo +15 more
wiley +1 more source
CD146+ bone marrow osteoprogenitors increase in the advanced stages of primary myelofibrosis
Haematologica, 2009 CD146+ bone marrow stromal cells have been recently recognized as clonogenic osteoprogenitors able to organize a complete hematopoietic microenvironment.
Claudio Tripodo +10 more
doaj +1 more source
Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis. [PDF]
, 1999 peer reviewedTranslocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly.
Albert Thiry +22 more
core +1 more source
Primary Myelofibrosis in the Prefibrotic Stage Presenting as Portal, Splenic, and Superior Mesenteric Vein Thrombosis: A Case Report and Review of the Literature [PDF]
, 2021 Emanuel Dias +5 more
openalex +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Since 2004, patients receiving imatinib with relapse in non‐marrow sites were given dasatinib to preserve control of leukemic marrow. Remissions in CNS and other organs began to be reported and are continuously observed to present. With resistance to one BCR::ABL1 tyrosine kinase inhibitor and sensitivity to a dual BCR::ABL1/SRC inhibitor ...
I. Cunningham +4 more
wiley +1 more source
Non-driver mutations in myeloproliferative neoplasm-associated myelofibrosis
Journal of Hematology & Oncology, 2017 We studied non-driver mutations in 62 subjects with myeloproliferative neoplasm (MPN)-associated myelofibrosis upon diagnosis, including 45 subjects with primary myelofibrosis (PMF) and 17 with post-polycythemia vera or post-essential thrombocythemia ...
Bing Li +11 more
doaj +1 more source
BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms. [PDF]
, 2013 Small molecule inhibition of the BET family of proteins, which bind acetylated lysines within histones, has been shown to have a marked therapeutic benefit in pre-clinical models of mixed lineage leukemia (MLL) fusion protein-driven leukemias.
Bannister, AJ +16 more
core +1 more source
Characteristics of Acyclovir‐Resistant Herpes Simplex Virus Infection in Hematological Patients
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Reema Shehadeh +7 more
wiley +1 more source
Primary autoimmune myelofibrosis: a report of three cases and review of the literature
Turkish Journal of Hematology, 2009 Myelofibrosis in association with autoimmune disorders has been consistently recognized in sporadic case reports over a number of years. Autoimmune myelofibrosis has been described most commonly in association with systemic lupus erythematosus (SLE).
Rakhee Kar, Shyamali Dutta, Seema Tyagi
doaj