Results 101 to 110 of about 4,938,261 (300)

Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow

open access: yesHaematologica, 2012
We investigated 15,542 patients with suspected BCR-ABL1- negative myeloproliferative or myelodysplastic/myeloproliferative neoplasm (including 359 chronic myelomonocytic leukemia) by a molecular marker set.
Susanne Schnittger   +9 more
doaj   +1 more source

Patient‐Reported Oral Symptoms and Their Impact on Well‐Being After Haematopoietic Cell Transplantation

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Oral complications may negatively influence outcomes of haematopoietic cell transplantation (HCT). A comprehensive view of oral symptoms and symptom burden post‐HCT is lacking. This study aimed to determine the prevalence, severity, and temporal relationships of oral symptoms and their impact on well‐being in the early post‐HCT phase.
Kristina Skallsjö   +14 more
wiley   +1 more source

Sex and degree of severity influence the prognostic impact of anemia in primary myelofibrosis: analysis based on 1109 consecutive patients

open access: yesLeukemia, 2018
Anemia is one of the major risk factors for survival in primary myelofibrosis (PMF). Current prognostic models in PMF, including the International Prognostic Scoring System (IPSS) [1], dynamic IPSS (DIPSS) [2] and DIPSS-plus [3], all list hemoglobin ...
M. Nicolosi   +7 more
semanticscholar   +1 more source

The Changing Epidemiology of Breakthrough Invasive Fungal Disease in Allogeneic Hematopoietic Stem Cell Transplant Recipients in the Era of Modified‐Release Posaconazole Prophylaxis

open access: yesTransplant Infectious Disease, EarlyView.
This single‐center retrospective cohort study on 300 allogeneic hematopoietic stem cell transplant recipients from January 2017 to May 2020, in which posaconazole modified release was the most common primary antifungal prophylaxis, demonstrated a breakthrough invasive fungal disease (bIFD) rate of 9%, with associated significant all‐cause mortality at ...
Shio Yen Tio   +7 more
wiley   +1 more source

Colorectal Liver Metastasis, Primary Gallbladder Carcinoma and Myelofibrosis Present Simultaneously in a Liver Resection Specimen

open access: yesCase Reports in Gastroenterology, 2015
Myelofibrosis and gallbladder carcinoma are both very rare diseases. This case report describes a patient with a history of myelofibrosis and colorectal carcinoma who was diagnosed with colorectal liver metastases.
Sophie A. Gray   +4 more
doaj   +1 more source

TP53 mutations and Polymorphisms in Primary Myelofibrosis, [PDF]

open access: yesBlood, 2011
Abstract Abstract 3840 Background: Patients with myeloproliferative neoplasms (MPN) harbor a multitude of somatic mutations involving JAK2, MPL, LNK, CBL, TET2, ASXL1, IDH1, IDH2, EZH2, DNMT3A, IKZF1 and TP53.
Sania, Raza   +8 more
openaire   +2 more sources

Targeted Therapy of Myelofibrosis

open access: yesКлиническая онкогематология, 2017
Background. Myelofibrosis (primary myelofibrosis, post-essential trombocythemia myelofibrosis, post-polycythemia myelofibrosis) is the most complex and pressing problem among all Ph-negative myeloproliferative diseases. The present article summarizes the
Ol’ga Yur’evna Vinogradova   +10 more
doaj   +1 more source

Management Strategies for Refractory Esophageal Varices

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley   +1 more source

Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations

open access: yesHaematologica, 2014
Somatic insertions/deletions in the calreticulin gene have recently been discovered to be causative alterations in myeloproliferative neoplasms. A combination of qualitative and quantitative allele-specific polymerase chain reaction, fragment-sizing ...
Hajnalka Andrikovics   +13 more
doaj   +1 more source

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