Results 111 to 120 of about 4,811,177 (246)
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi+5 more
wiley +1 more source
The WHO System is an international effort to standardise category definitions, establish the key diagnostic cytopathological features of entities of the lung, propose the best use of ancillary tests in lung specimens, encourage the use of standardised pathology reports containing essential components in an integrated report and propose estimates of the
Zahra Maleki, Sule Canberk, Andrew Field
wiley +1 more source
Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis
Estrov and collaborators examine the role of fibrocytes in primary myelofibrosis and propose a novel therapeutic approach.
S. Verstovsek+17 more
semanticscholar +1 more source
Imaging Findings of Congenital Distal Interphalangeal Joint Dysplasia in a 3‐Month‐Old Friesian Foal
ABSTRACT A 3‐month‐old Friesian colt presented with severe, progressive distal limb lameness in two limbs. Radiographic and postmortem full‐body CT imaging revealed severe articular deforming osteolysis and osteoproliferation at the dorsodistal navicular bone margin and the adjacent distal phalanx proximo‐palmar/proximo‐plantar margin in two limbs ...
Emmie J. M. Giessen+3 more
wiley +1 more source
Megakaryocytes morphology in idiopathic (primary) myelofibrosis
SummaryBackgroundThe cause of idiopathic myelofibrosis (IM) originating from a haemopoietic stem cells with development of secondary marrow fibrosis is unknown. Increased production of platelet-derived growth factor by megakaryocytes causes amplified activity of fibroblasts.
Iryna N. Kabachenko+2 more
openaire +2 more sources
A 67-year-old male patient who was diagnosed with primary myelofibrosis 4 years ago did not respond to conventional therapies. The splenomegaly progressively increased, which caused spleen infarctions and led to the decision to perform a splenectomy ...
Meltem Aylı+2 more
doaj +1 more source
What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson+5 more
wiley +1 more source
Leukemic transformation is the most dreaded complication in patients with myeloproliferative neoplasms (MPN); overall risk is estimated at 14% for primary myelofibrosis (PMF), 7% for polycythemia vera (PV) and 4% for essential thrombocythemia (ET).
M. Mudireddy+5 more
semanticscholar +1 more source
Primary and Secondary Myelofibrosis: Its Relationship to "PNH-like Defect" [PDF]
Chi-yen Kuo+2 more
openalex +1 more source
U2AF1 mutation types in primary myelofibrosis: phenotypic and prognostic distinctions
myeloid leukemia. Blood. 2013;121:2213–23. 4. Yin JA, O’Brien MA, Hills RK, Daly SB, Wheatley K, Burnett AK. Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of
A. Tefferi+6 more
semanticscholar +1 more source