Results 111 to 120 of about 4,938,261 (300)
[Philadelphia chromosome positive acute lymphoblastic leukemia blast crisis from primary myelofibrosis: a case report]. [PDF]
, 2023 Yaxin Liu +4 more
openalex +1 more source
Leptin receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis
Nature Cell Biology, 2017 Bone marrow fibrosis is a critical component of primary myelofibrosis (PMF). However, the origin of the myofibroblasts that drive fibrosis is unknown.
M. Decker +6 more
semanticscholar +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Long-term results of splenectomy in primary myelofibrosis
Онкогематология, 2014 The estimation of immediate and long-term results after splenectomy depending on indications and contra-indications for 18 primary myelofibrosis (PMF) patients was shown.
L. M. Meshcheryakova +5 more
doaj +3 more sources
Efficacy of Momelotinib in Myelofibrosis Patients: Results From a Multicenter Study
European Journal of Haematology, Volume 116, Issue 1, Page 23-30, January 2026.ABSTRACT Momelotinib, a novel JAK1/2 inhibitor with inhibitory activities on activin A receptor type I, has shown breakthrough clinical efficacy in patients with myelofibrosis (MF) and anemia, a disease‐related manifestation of challenging management. In this retrospective real‐life multicenter Italian study, we investigated the safety and efficacy of ...
Maria Carmen Martorelli +34 more
wiley +1 more source
Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis
Haematologica, 2020 There is prevailing evidence to suggest a decisive role for platelet-derived growth factors (PDGF) and their receptors in primary myelofibrosis. While PDGF receptor β (PDGFRβ) expression is increased in bone marrow stromal cells of patients correlating ...
Frederike Kramer +5 more
doaj +1 more source
European Journal of Haematology, Volume 116, Issue 1, Page 93-97, January 2026.ABSTRACT Previous studies investigating the role of TP53 mutations in chronic phase MPN have yielded inconsistent results. As such, the clinical relevance of these mutations remains to be elucidated. We report a case of a 67‐year‐old woman with a leukemic transformation of a post‐polycythaemia vera myelofibrosis (post‐PV MF) that culminated in the rare
Isidor Minović +8 more
wiley +1 more source
Haematologica, 2019 In this study we interrogated the DNA methylome of myelofibrosis patients using high-density DNA methylation arrays. We detected 35,215 differentially methylated CpG, corresponding to 10,253 genes, between myelofibrosis patients and healthy controls ...
Nicolás Martínez-Calle +15 more
doaj +1 more source
Localized Tuberculosis and Myelofibrosis with Myeloid Metaplasia : An extremely unusual presentation [PDF]
, 1996 Myelofibrosis with myeloid metaplasia (MMM) is usually considered primary agnogenic, however, it may be secondary to various diseases, The association of tuberculosis with MMIM is exceedingly rare, however, the pathogenetic relationship between the two ...
Muzaffar, Suhail
core +1 more source
Targeted deep sequencing in primary myelofibrosis.
Blood Advances, 2016 A myeloid neoplasm-relevant 27-gene panel was used for next-generation sequencing of bone marrow or whole blood DNA in 182 patients with primary myelofibrosis (PMF).
A. Tefferi +7 more
semanticscholar +1 more source