Results 231 to 240 of about 4,811,177 (246)

An unusual presentation of primary myelofibrosis

Indian Journal of Tuberculosis, 2018
Extramedullary hematopoisis (EMH) normally occurs in fetal life, but it is pathological in later life and most of the time because of underlying marrow diseases. Sometimes EMH tissue can present with large masses which can cause compressive and constitutional symptoms. They can be wrongly diagnosed as malignancy and pulmonary tuberculosis. Here in this
Prateek Tiwari, Kanchan Muhrerkar, Vandana Mahajan   +2 more
openaire   +2 more sources

Ruxolitinib for the treatment of primary myelofibrosis

American Journal of Health-System Pharmacy, 2014
The pharmacology, pharmacokinetics, pharmacogenomics, clinical efficacy, and safety profile of ruxolitinib for the treatment of primary myelofibrosis are reviewed.Ruxolitinib, an oral tyrosine kinase inhibitor that targets the Janus-associated kinases (JAKs) 1 and 2, has been recently approved for the treatment of patients with intermediate- or high ...
openaire   +3 more sources

Primary myelofibrosis

2010
Myelofibrosis is a reactive process common to many malignant and benign disorders. Primary myelofibrosis is a chronic myeloproliferative disorder of unknown aetiology that involves a multipotent haemopoietic progenitor cell and results in abnormalities in red cell, white cell, and platelet production in association with marrow fibrosis and ...
openaire   +1 more source

Cytogenetic and molecular studies in primary myelofibrosis

Cancer Genetics and Cytogenetics, 1989
Cytogenetic and molecular data of three patients affected by primary myelofibrosis with myeloid metaplasia (PMMM) evolving to blastic crisis are reported. The cytogenetic findings were uncommon. The first patient (female) showed an idic(X)(q13) as the sole alteration in chronic phase, with an additional r(7) in 67% of the cells of the blast crisis; the
Emilia G., Temperani P., Ferrari S., Zucchini P., Tagliafico E., Selleri L., Torelli G., Artusi T., Torelli U.   +8 more
openaire   +4 more sources

Current and Emerging Therapies in Primary Myelofibrosis

Cardiovascular & Hematological Disorders-Drug Targets, 2012
Primary myelofibrosis is a clonal hematopoietic disorder characterized by ineffective hematopoiesis and progressive bone marrow fibrosis. Patients with high risk myelofibrosis as determined by their advanced age, degree of anemia, leukocytosis, constitutional symptoms and high percentage of circulating blasts have a very short median survival of 2 ...
Murali Janakiram, Radha Raghupathy, Sabarish Ayyappan   +2 more
openaire   +3 more sources

Extramedullary blastic transformation of primary myelofibrosis in the form of disseminated myeloid sarcoma: a case report and review of the literature

Clinical and Experimental Medicine (Testo stampato), 2020
G. Coltro, F. Mannelli, F. Vergoni, R. Santi, D. Massi, L. Siliani, A. Marzullo, S. Bonifacio, E. Pelo, Annalisa Pacilli, C. Paoli, A. Franci, L. Calabresi, A. Bosi, A. Vannucchi, P. Guglielmelli   +15 more
semanticscholar   +1 more source

A provider's guide to primary myelofibrosis: pathophysiology, diagnosis, and management.

Blood reviews, 2020
Benjamin Garmezy, J. Schaefer, Jessica Mercer, M. Talpaz   +3 more
semanticscholar   +1 more source

ABOUT PRIMARY MYELOFIBROSIS:

European Journal of Haematology, 1988
openaire   +3 more sources

Primary Myelofibrosis with Myeloid Metaplasia

Medical Clinics of North America, 1956
J.M. Stickney, Alan S. Medoff
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Primary and Secondary Myelofibrosis

The Journal of Nervous and Mental Disease, 1945
A Lowell Erf, A Peter Herbut
openaire   +2 more sources