Results 31 to 40 of about 108,257 (197)
Biology and Treatment of Primary Myelofibrosis [PDF]
Hematology, 2007 Abstract Primary myelofibrosis (PMF) is a chronic myeloproliferative disorder associated with an average survival of less than 5 years. Therapy for PMF has used chemotherapeutic agents, immunomodulatory drugs, or biological-response modifiers that have not always been directed at the biological processes that underlie the origins of PMF.
Ronald Hoffman, Damiano Rondelli
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Revista Brasileira de Hematologia e Hemoterapia, 2014 Objective: The aim of this work was to demonstrate a possible relationship between anti-latency-associated peptide human latent transforming growth factor beta 1 (latent TGF-β1) expression in megakaryocytes and microvascular density in bone marrow ...
Cesar Cilento Ponce +3 more
doaj +1 more source
From primary myelofibrosis to chronic myeloid leukemia, BCR::ABL1+ B-Lymphoblastic leukemia, and back to primary myelofibrosis: An illustration of dynamic clonal evolution. [PDF]
EJHaemThe simultaneous detection of BCR::ABL1 and JAK2 V617F was rarely reported and their clonal relationship and dynamic clonal shift were not characterized. Here, we described a unique case with the initial presentation as JAK2 V617F+ primary myelofibrosis,
Wang D, Kamata W, Ye F, You MJ.
europepmc +2 more sources
On strongly primary monoids, with a focus on Puiseux monoids [PDF]
J. Algebra 567 (2021), No. 1, pp. 310-345, 2019 Primary and strongly primary monoids and domains play a central role in the ideal and factorization theory of commutative monoids and domains. It is well-known that primary monoids satisfying the ascending chain condition on divisorial ideals (e.g., numerical monoids) are strongly primary; and the multiplicative monoid of non-zero elements of a one ...
arxiv +1 more source
Derived Langlands VII: The PSH Algebra of Products of General Linear Groups [PDF]
arXiv, 2022 In this article we put a very elaborate PSH-like structure on the $R_{+}(-)$ groups of products of finite general linear groups. This is not the case we want. Firstly one would really want the actual big PSH algebra of products of general linear groups with entries in a characteristic zero $p$-adic local field.
arxiv
Treatment of primary myelofibrosis.
Turkish journal of haematology : official journal of Turkish Society of Haematology, 2009 Şinasi Özsoylu
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Haematologica, 2011 Risk stratification in primary myelofibrosis is currently based on two international prognostic scoring systems, neither of which takes into consideration red blood cell transfusion-dependency.
Chiara Elena +9 more
doaj +1 more source
Primary autoimmune myelofibrosis: A case report in a child
eJHaem, 2020 Autoimmune myelofibrosis (AIMF) is an uncommon cause of myelofibrosis associated with favorable outcome. Primary AIMF, AIMF without a known systemic autoimmune disorder, has been described in adults, but never in children. Here, we present, for the first
Zufit Hexner‐Erlichman +7 more
doaj +1 more source
Targeted sequencing of candidate gene regions for myelofibrosis in dogs
Journal of Veterinary Internal Medicine, 2022 Background Myelofibrosis often lacks an identifiable cause in dogs. In humans, most primary myelofibrosis cases develop secondary to driver mutations in JAK2, CALR, or MPL.
Amelia G. Campbell +7 more
doaj +1 more source
TP53 mutations and Polymorphisms in Primary Myelofibrosis, [PDF]
Blood, 2011 Abstract Abstract 3840 Background: Patients with myeloproliferative neoplasms (MPN) harbor a multitude of somatic mutations involving JAK2, MPL, LNK, CBL, TET2, ASXL1, IDH1, IDH2, EZH2, DNMT3A, IKZF1 and TP53.
Rhett P. Ketterling +8 more
openaire +4 more sources