Results 51 to 60 of about 108,257 (197)

Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes

Haematologica, 2011
Background The myeloproliferative neoplasms, essential thrombocytosis, polycythemia vera and primary myelofibrosis, share the same acquired genetic lesion, but the concept of JAK2 V617F serving as the sole lesion responsible for these neoplasms is under ...
Brady L. Stein, Donna M. Williams, Christine O’Keefe, Ophelia Rogers, Roxann G. Ingersoll, Jerry L. Spivak, Amit Verma, Jarek P. Maciejewski, Michael A. McDevitt, Alison R. Moliterno   +9 more
doaj   +1 more source

Primary decomposition of modules: a computational differential approach [PDF]

arXiv, 2021
We study primary submodules and primary decompositions from a differential and computational point of view. Our main theoretical contribution is a general structure theory and a representation theorem for primary submodules of an arbitrary finitely generated module over a polynomial ring.
arxiv  

S-1-absorbing primary submodules [PDF]

arXiv, 2022
In this work, we introduce the notion of $S$-1-absorbing primary submodule as an extension of 1-absorbing primary submodule. Let $S$ be a multiplicatively closed subset of a ring $R$ and $M$ be an $R$-module. A submodule $N$ of $M$ with $(N:_{R}M)\cap S=\emptyset$ is said to be $S$-1-absorbing primary if whenever $abm\in N$ for some non-unit $a,b\in R$
arxiv  

Analysis of MicroRNA -155-5p Expression in Patients with Primary Myelofibrosis.

مجلة كلية الطب
Background: Primary myelofibrosis is a chronic myeloproliferative neoplasm characterized by abnormal megakaryocyte proliferation and fibrosis that destroys healthy bone marrow.
Sarah I. Khaleel, Jaffar N. AlAlsaidissa   +1 more
doaj   +1 more source

CD133 marks a stem cell population that drives human primary myelofibrosis

Haematologica, 2015
Primary myelofibrosis is a myeloproliferative neoplasm characterized by bone marrow fibrosis, megakaryocyte atypia, extramedullary hematopoiesis, and transformation to acute myeloid leukemia.
Ioanna Triviai, Thomas Stübig, Birte Niebuhr, Kais Hussein, Asterios Tsiftsoglou, Boris Fehse, Carol Stocking, Nicolaus Kröger   +7 more
doaj   +1 more source

CD146+ bone marrow osteoprogenitors increase in the advanced stages of primary myelofibrosis

Haematologica, 2009
CD146+ bone marrow stromal cells have been recently recognized as clonogenic osteoprogenitors able to organize a complete hematopoietic microenvironment.
Claudio Tripodo, Andrea Di Bernardo, Maria Paola Ternullo, Carla Guarnotta, Rossana Porcasi, Sabrina Ingrao, Umberto Gianelli, Emanuela Boveri, Emilio Iannitto, Giovanni Franco, Ada Maria Florena   +10 more
doaj   +1 more source

Hepatic nodule: a case of primary myelofibrosis [PDF]

Case Reports, 2011
Primary myelofibrosis is one of the entities that may manifest with lesions of extramedullary haematopoiesis, especially in spleen and liver. The authors report a case of primary myelofibrosis presenting incidentally as an intrahepatic focal lesion of extramedullary haematopoiesis, a rare occurrence that highlights the challenge of hepatic nodule ...
Filipe S. Cardoso, José Simão Miranda, Joao Pires, João Araújo   +3 more
openaire   +3 more sources

Rituximab for the Management of an Australian Cohort of Treatment Refractory Mucous Membrane Pemphigoid

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Mucous membrane pemphigoid (MMP) has a broad range of clinical manifestations, from relatively benign self‐limiting oral lesions to significant scarring (cicatrizing) of the oral, nasal and ocular tissues with severe functional impairment and morbidity.
Bronte Jeffrey, Mark Schifter, Elizabeth Arena, Emily Sullivan, Stephanie Rose, David Joo, David Campbell, Suzanne Culican, David McDonald, Ming Wei Lin   +9 more
wiley   +1 more source

Non-driver mutations in myeloproliferative neoplasm-associated myelofibrosis

Journal of Hematology & Oncology, 2017
We studied non-driver mutations in 62 subjects with myeloproliferative neoplasm (MPN)-associated myelofibrosis upon diagnosis, including 45 subjects with primary myelofibrosis (PMF) and 17 with post-polycythemia vera or post-essential thrombocythemia ...
Bing Li, Robert Peter Gale, Zefeng Xu, Tiejun Qin, Zhen Song, Peihong Zhang, Jie Bai, Lei Zhang, Yue Zhang, Jinqin Liu, Gang Huang, Zhijian Xiao   +11 more
doaj   +1 more source

Development of Dermatomyositis in a Patient with Primary Myelofibrosis

Hematology, 2001
It is known that immunologic mechanisms play an important role in the disease process of some patients with idiopathic myelofibrosis. Patients with idiopathic myelofibrosis have an increased incidence of autoantibodies and circulating immune complexes.
TAŞKAPAN, HÜLYA, Gürsoy, S., Oymak, O., ÇETİN, MEHMET YAVUZ, Özbakir, Ö.   +4 more
openaire   +3 more sources