Results 51 to 60 of about 25,990 (142)

Colorectal Liver Metastasis, Primary Gallbladder Carcinoma and Myelofibrosis Present Simultaneously in a Liver Resection Specimen

Case Reports in Gastroenterology, 2015
Myelofibrosis and gallbladder carcinoma are both very rare diseases. This case report describes a patient with a history of myelofibrosis and colorectal carcinoma who was diagnosed with colorectal liver metastases.
Sophie A. Gray, Menno H. Raber, Esther Provoost, Gert-Jan Toes, Joost M. Klaase   +4 more
doaj   +1 more source

BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms. [PDF]

, 2013
Small molecule inhibition of the BET family of proteins, which bind acetylated lysines within histones, has been shown to have a marked therapeutic benefit in pre-clinical models of mixed lineage leukemia (MLL) fusion protein-driven leukemias.
Bannister, AJ, Barbieri, I, Calero-Nieto, FJ, Cannizzaro, E, Dawson, MA, Godfrey, A, Gottgens, B, Green, AR, Huntly, B, Kouzarides, T, Li, J, Nangalia, J, Prinjha, RK, Rioja, I, Robson, S, Wiese, M, Wyspiańska, BS   +16 more
core   +1 more source

Long-term results of splenectomy in primary myelofibrosis

Онкогематология, 2014
The estimation of immediate and long-term results after splenectomy depending on indications and contra-indications for 18 primary myelofibrosis (PMF) patients was shown.
L. M. Meshcheryakova, L. G. Kovaleva, S. R. Karagyulyan, L. Yu. Kolosova, O. V. Porotkova, Ye. A. Semenova   +5 more
doaj   +3 more sources

Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations

Haematologica, 2014
Somatic insertions/deletions in the calreticulin gene have recently been discovered to be causative alterations in myeloproliferative neoplasms. A combination of qualitative and quantitative allele-specific polymerase chain reaction, fragment-sizing ...
Hajnalka Andrikovics, Tunde Krahling, Katalin Balassa, Gabriella Halm, Andras Bors, Magdalena Koszarska, Arpad Batai, Janos Dolgos, Judit Csomor, Miklos Egyed, Andrea Sipos, Peter Remenyi, Attila Tordai, Tamas Masszi   +13 more
doaj   +1 more source

Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis

Haematologica, 2020
There is prevailing evidence to suggest a decisive role for platelet-derived growth factors (PDGF) and their receptors in primary myelofibrosis. While PDGF receptor β (PDGFRβ) expression is increased in bone marrow stromal cells of patients correlating ...
Frederike Kramer, Jens Dernedde, Artur Mezheyeuski, Rudolf Tauber, Patrick Micke, Kai Kappert   +5 more
doaj   +1 more source

Acute massive myelofibrosis with acutelymphoblastic leukemia [PDF]

, 2009
Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare.
Barış Malbora, Bülent Celasun, Feride Iffet Şahin, Meltem Gülşan, Namık Özbek, Zekai Avcı   +5 more
core  

Budd-Chiari syndrome recurring in a transplanted liver [PDF]

, 1983
A patient with Budd-Chiari syndrome who underwent orthotopic liver transplantation and developed recurrent disease is described. The immediate postoperative period was complicated by multiple thrombotic episodes, followed by a period of apparent ...
Andrew Dekker, Asbury, Bras, Calne, Dane R. Boggs, David H. Van Thiel, Howard J. Seltman, Mitchel, Parker, Putnam, Takeuchi, Thomas E. Starzl   +11 more
core   +1 more source

Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regulated

Haematologica, 2019
In this study we interrogated the DNA methylome of myelofibrosis patients using high-density DNA methylation arrays. We detected 35,215 differentially methylated CpG, corresponding to 10,253 genes, between myelofibrosis patients and healthy controls ...
Nicolás Martínez-Calle, Marien Pascual, Raquel Ordoñez, Edurne San José Enériz, Marta Kulis, Estíbaliz Miranda, Elisabeth Guruceaga, Víctor Segura, María José Larráyoz, Beatriz Bellosillo, María José Calasanz, Carles Besses, José Rifón, José I. Martín-Subero, Xabier Agirre, Felipe Prosper   +15 more
doaj   +1 more source

Risk of other Cancers in Families with Melanoma : Novel Familial Links [PDF]

, 2017
A family history of cutaneous melanoma ('melanoma') is a well-established risk factor for melanoma. However, less is known about the possible familial associations of melanoma with other discordant cancers. A risk for discordant cancer may provide useful
Frank, Christoph, Hemminki, Akseli, Hemminki, Kari, Sundquist, Jan   +3 more
core   +1 more source

Aktualitások a primer myelofibrosis ellátásában | Actualities in the management of primary myelofibrosis [PDF]

, 2016
Absztrakt A primer myelofibrosis a Philadelphia-negatív krónikus myeloid neoplasiák közé tartozó ritka kórkép, amelyre jellemző a cytopeniák és hepatosplenomegalia kialakulása.
Borbényi, Zita, Illés, Árpád, Marton, Imelda, Simon, Zsófia   +3 more
core   +1 more source