Results 61 to 70 of about 108,257 (197)

Adaptive dosing of high‐dose busulfan in real‐world adult patients undergoing haematopoietic cell transplant conditioning

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1171-1181, April 2025.
Aim To evaluate the effectiveness of a Bayesian adaptive dosing strategy in achieving target busulfan exposure in adult patients undergoing haematopoietic cell transplantation (HCT). Methods This study included 71 adult patients scheduled to receive high‐dose busulfan. Busulfan was administered to achieve a cumulative area under the curve (AUC) of 66.0 
Dorian Protzenko, Benjamin Bouchacourt, Laure Carriat, Paul Maroselli, Clara Boéri, Raynier Devillier, Joseph Ciccolini   +6 more
wiley   +1 more source

Primary autoimmune myelofibrosis: a report of three cases and review of the literature

Turkish Journal of Hematology, 2009
Myelofibrosis in association with autoimmune disorders has been consistently recognized in sporadic case reports over a number of years. Autoimmune myelofibrosis has been described most commonly in association with systemic lupus erythematosus (SLE).
Rakhee Kar, Shyamali Dutta, Seema Tyagi
doaj  

Perspective: Speculative role of Tmp21 mediated protein secretory pathway during endoplasmic reticulum (ER) stress induced chronic inflammation [PDF]

arXiv, 2016
By deploying myelofibrosis as the disease context, I wish to propose that increased availability of Tmp21 (an NFAT gene target) induces aberrant protein secretion from the ER contributing to pathological consequences, which has not been elucidated before.
arxiv  

CLINICAL AND HEMATOLOGICAL ASPECTS OF PRIMARY MYELOFIBROSIS

, 2023
Primary myelofibrosis (PMF) is a chronic clonal stem cell disease that causes an accumulation of marrow fibrosis and dysfunction, hypermetabolic states, and extramedullary myeloid metaplasia. The onset of the disease is often asymptomatic, which causes a late referral to a specialist, the disease being already confirmed in the fibrotic stage with a ...
Andrianova, A., Musteață, L.
openaire   +2 more sources

When, which and how to switch: Navigating JAK inhibitors in myelofibrosis

British Journal of Haematology, EarlyView.
Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan, Imran Omerdeen, Bethan Psaila   +2 more
wiley   +1 more source

Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow

Haematologica, 2012
We investigated 15,542 patients with suspected BCR-ABL1- negative myeloproliferative or myelodysplastic/myeloproliferative neoplasm (including 359 chronic myelomonocytic leukemia) by a molecular marker set.
Susanne Schnittger, Ulrike Bacher, Christiane Eder, Frank Dicker, Tamara Alpermann, Vera Grossmann, Alexander Kohlmann, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach   +9 more
doaj   +1 more source

Pseudo-Primary, Classical Prime and Pseudo-Classical Primary Elements in Lattice Modules [PDF]

arXiv, 2020
In this paper, we introduce the notion of pseudo-primary elements and pseudo-classical primary elements in an $L$-module $M$ and obtain their characterizations. The aim of the paper is to show $rad(N)\in M$, the radical of $N\in M$ is prime if $N$ is either pseudo-primary or pseudo-classical primary.
arxiv  

A Case of Primary Autoimmune Myelofibrosis [PDF]

The Korean Journal of Hematology, 2009
Myelofibrosis is usually observed in association with hematologic malignancies or metastatic solid tumors, but it has rarely been reported in patients who suffer with autoimmune disorders. Autoimmune myelofibrosis is a distinct clinicopathologic entity and it can occur alone or in association with autoimmune disorders, and the final result is chronic ...
Jeong Yeal Ahn, Pil Hwan Park, Jinny Park, Soon Ho Park, Yiel Hea Seo, Kyung-Hee Kim, Jung-Eun Kim, Young Hee Song   +7 more
openaire   +1 more source

Olutasidenib demonstrates significant clinical activity in mutated IDH1 acute myeloid leukaemia arising from a prior myeloproliferative neoplasm

British Journal of Haematology, Volume 206, Issue 4, Page 1121-1128, April 2025.
Outcomes with olutasidenib appear appreciably better than previous reports of other therapies for blast‐phase myeloproliferative neoplasm (MPN), supporting the role for olutasidenib‐based therapy in mIDH1 AML secondary to MPN. Summary Acute myeloid leukaemia (AML) arising from a myeloproliferative neoplasm (MPN) is more aggressive and less responsive ...
Stéphane De Botton, Christian Récher, Jorge Cortes, Antonio Curti, Pierre Fenaux, Pierre Peterlin, Arnaud Pigneux, Karen Yee, Andrew Wei, Alice Mims, Gary Schiller, Mwe Mwe Chao, Hua Tian, Justin M. Watts   +13 more
wiley   +1 more source

Uniformly 2-absorbing primary ideals of commutative rings [PDF]

arXiv, 2015
In this study, we introduce the concept of "uniformly 2-absorbing primary ideals" of commutative rings, which imposes a certain boundedness condition on the usual notion of 2-absorbing primary ideals of commutative rings. Then we investigate some properties of uniformly 2-absorbing primary ideals of commutative rings with examples. Also, we investigate
arxiv