Results 31 to 40 of about 20,080,837 (239)

Primary open-angle glaucoma genes [PDF]

Eye, 2011
A substantial fraction of glaucoma has a genetic basis. About 5% of primary open angle glaucoma (POAG) is currently attributed to single-gene or Mendelian forms of glaucoma (ie glaucoma caused by mutations in myocilin or optineurin). Mutations in these genes have a high likelihood of leading to glaucoma and are rarely seen in normal subjects.
openaire   +2 more sources

Molecular genetics of primary open-angle glaucoma

Indian Journal of Ophthalmology, 2023
Glaucoma is a series of linked optic diseases resulting in progressive vision loss and total blindness due to the acquired loss of retinal ganglion cells.
Manoj Yadav, Aarti Bhardwaj, Anshu Yadav, Rima Dada, Mukesh Tanwar   +4 more
doaj   +1 more source

Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]

, 2012
20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A, Gurbaxani, A, Taylor, SR, Lightman, S   +3 more
core   +1 more source

Association between hypertriglyceridemia and open angle glaucoma: A case report

Indian Journal of Ophthalmology, 2019
Hypertriglyseridemia is a metabolic disorder that can cause vascular dysfucntion and be causally associated with glaucoma. Herein we present the case of a 16-year-old boy with hypertriglyseridemia with open-angle glaucoma.
Mayuri Bakulesh Khamar, Arpita P Sthapak, D Vijayevarshcini, Priyanka M Patel   +3 more
doaj   +1 more source

Hospitalization characteristics of patients with glaucoma in Central and West Serbia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. Glaucoma is a chronic disease that impairs the optic nerve irreversibly and can lead to serious loss of vision and blindness. As the most frequent out of all, primary open-angle glaucoma has a worldwide incidence of 2.4 million ...
Kocić Sanja, Radević Svetlana, Simić-Vukomanović Ivana, Janićijević Katarina, Janićijević-Petrović Mirjana, Mihailović Nataša   +5 more
doaj   +1 more source

An investigation of genetic risk factors in primary open-angle glaucoma [PDF]

, 2009
Primary open-angle glaucoma (POAG) is a multifactorial disease with a strong genetic component. Notably however, few genes have been robustly associated with POAG in the general population.
Park, S.
core  

OPA1 increases the risk of normal but not high tension glaucoma

, 2010
Background Primary open angle glaucoma is a progressive optic neuropathy characterised by the selective loss of retinal ganglion cells, pathological optic disc cupping and visual field defects.
Griffiths, P. G., Birch, M. K., Andrews, R. M., Chinnery, P. F., Hudson, G., Yu-Wai-Man, P., Stewart, J .D.   +6 more
core   +1 more source

Spectral-Domain Optical Coherence Tomography for Early Detection of Primary Open-Angle, Angle-Closure, and Normal-Tension Glaucoma in an Asian Population

, 2023
Purpose: We investigated the diagnostic capability of spectral-domain optical coherence tomography (SD-OCT) for different types of early glaucoma among the Chinese population in Taiwan.
Wu, Chao-Wei; Chang, Yue-Cune ; Chen, Hsin-Yi, Wu, Chao-Wei;Chang, Yue-Cune;Chen, Hsin-Yi   +1 more
core   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source

GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma

Nature Communications
The etiology of primary open angle glaucoma is constituted by both intraocular pressure-dependent and intraocular pressure-independent mechanisms.
Yu Huang, Denis Plotnikov, Huan Wang, Danli Shi, Cong Li, Xueli Zhang, Xiayin Zhang, Shulin Tang, Xianwen Shang, Yijun Hu, Honghua Yu, Hongyang Zhang, Jeremy A. Guggenheim, Mingguang He   +13 more
doaj   +1 more source