Results 31 to 40 of about 66,541 (257)
Clinical Ophthalmology, 2014 Purpose The purpose of this study was to compare outcomes of subjects with open-angle glaucoma (OAG) not controlled on one medication who underwent either implantation of two iStent inject® trabecular micro-bypass devices or received medical therapy ...
A. Fea +7 more
semanticscholar +1 more source
Biomarkers of primary open-angle glaucoma [PDF]
Expert Review of Ophthalmology, 2010 Primary open-angle glaucoma (POAG) is a primary neuronal disease of the optic nerve without a definable cause, and is often associated with increased intraocular pressure. Worldwide, POAG is the second leading cause of blindness; there are 45 million people today with POAG and bilateral blindness is present in 4.5 million of these.
Paul A, Knepper +2 more
openaire +2 more sources
MicroRNAs as biomarkers in glaucoma and potential therapeutic targets
Neural Regeneration Research, 2022 Glaucoma is a neurodegenerative disease in which optic nerve damage and visual field defects occur. It is a leading cause of irreversible blindness. Its pathogenesis is largely unknown although several risk factors have been identified, with an increase ...
Bridget Martinez, Philip V Peplow
doaj +1 more source
PLoS ONE, 2011 BackgroundOpen-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
Alberto Izzotti +3 more
doaj +1 more source
American journal of ophthalmology-glaucoma, 2020 PURPOSE To evaluate the efficacy and safety of omidenepag isopropyl (OMDI), a selective, non-prostaglandin, prostanoid EP2 receptor agonist, in Japanese patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT).
M. Aihara +5 more
semanticscholar +1 more source
Nature Genetics, 2018 Glaucoma is the leading cause of irreversible blindness globally1. Despite its gravity, the disease is frequently undiagnosed in the community2. Raised intraocular pressure (IOP) is the most important risk factor for primary open-angle glaucoma (POAG)3,4.
A. Khawaja +15 more
semanticscholar +1 more source
Ganglion Cell Complex Thickness and Macula Vessel Density Loss in Primary Open Angle Glaucoma
Ophthalmology (Rochester, Minn.), 2020 Purpose: To characterize the rate of change of ganglion cell complex(GCC) thickness and macula vessel density in healthy, pre-perimetric glaucoma and primary open angle glaucoma(POAG) eyes. Design: Prospective, longitudinal study.
Huiyuan Hou +7 more
semanticscholar +1 more source
Effect of myricetin on primary open-angle glaucoma [PDF]
Translational Neuroscience, 2018 Abstract Background Primary open angle glaucoma (POAG) is the most common form of glaucoma, with a multifactorial etiology that results in retinal ganglion cell death and loss of vision. In this study, we assessed the effects of myricetin on the trabecular meshwork cells in POAG.
Yang Qing, Li Ying, Luo Lin
openaire +3 more sources
Molecular genetics of primary open-angle glaucoma
Indian Journal of Ophthalmology, 2023 Glaucoma is a series of linked optic diseases resulting in progressive vision loss and total blindness due to the acquired loss of retinal ganglion cells.
Manoj Yadav +4 more
doaj +1 more source
Graefe's Archive for Clinical and Experimental Ophthalmology, 2019 PurposeTo evaluate the effectiveness of an ab interno subconjunctival gelatin implant as primary surgical intervention in reducing intraocular pressure (IOP) and IOP-lowering medication count in medically uncontrolled moderate primary open-angle glaucoma
H. Reitsamer +6 more
semanticscholar +1 more source