Results 31 to 40 of about 55,462 (212)
PLoS ONE, 2011 BackgroundOpen-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
Alberto Izzotti +3 more
doaj +1 more source
Detection of glaucoma in a cohort of chinese subjects with systemic hypertension [PDF]
, 2013 Purpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via ...
Chan, J +4 more
core +1 more source
A prospective, longitudinal, observational cohort study examining how glaucoma affects quality of life and visually-related function over 4 years: design and methodology [PDF]
, 2015 BACKGROUND: The aim of this study is to summarize the design and methodology of a prospective, longitudinal, observational cohort study to investigate how glaucoma affects patients’ quality of life and visually-related function over a 4-year period ...
Feyzahan Ekici +8 more
core +1 more source
Delta Journal of Ophthalmology, 2022 Aim The aim of this study was to show if primary open-angle glaucoma (POAG) is associated with structural neurodegenerative changes along the visual pathway. Patients and methods The patients included in the study were divided into two groups: group 1 (200 patients having POAG) and ...
Ahmed A. Alhagaa, Rehab M. Habib
openaire +1 more source
Molecular genetics of primary open-angle glaucoma
Indian Journal of Ophthalmology, 2023 Glaucoma is a series of linked optic diseases resulting in progressive vision loss and total blindness due to the acquired loss of retinal ganglion cells.
Manoj Yadav +4 more
doaj +1 more source
The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in Caucasians with primary open angle glaucoma [PDF]
, 2012 Background: Loss of vision in glaucoma is due to apoptotic retinal ganglion cell loss. While p53 modulates apoptosis, gene association studies between p53 variants and glaucoma have been inconsistent.
Alex W. Hewitt +12 more
core +5 more sources
Association between hypertriglyceridemia and open angle glaucoma: A case report
Indian Journal of Ophthalmology, 2019 Hypertriglyseridemia is a metabolic disorder that can cause vascular dysfucntion and be causally associated with glaucoma. Herein we present the case of a 16-year-old boy with hypertriglyseridemia with open-angle glaucoma.
Mayuri Bakulesh Khamar +3 more
doaj +1 more source
Hospitalization characteristics of patients with glaucoma in Central and West Serbia [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2019 Introduction/Objective. Glaucoma is a chronic disease that impairs the optic nerve irreversibly and can lead to serious loss of vision and blindness. As the most frequent out of all, primary open-angle glaucoma has a worldwide incidence of 2.4 million ...
Kocić Sanja +5 more
doaj +1 more source
Advanced Science, EarlyView.High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao +10 more
wiley +1 more source
GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma
Nature CommunicationsThe etiology of primary open angle glaucoma is constituted by both intraocular pressure-dependent and intraocular pressure-independent mechanisms.
Yu Huang +13 more
doaj +1 more source