Results 51 to 60 of about 66,541 (257)

XEN® Gel Stent compared to PRESERFLO™ MicroShunt implantation for primary open‐angle glaucoma: two‐year results

Acta ophthalmologica, 2020
To evaluate the long‐term efficacy and safety of two minimally invasive glaucoma surgery implants with a subconjunctival drainage approach: the XEN45 Gel Stent® (Xen) implant and the PRESERFLO™ MicroShunt (MicroShunt).
L. Scheres, S. Kujovic-Aleksov, W. Ramdas, R. D. De Crom, Lianne C G Roelofs, T. Berendschot, C. Webers, H. Beckers   +7 more
semanticscholar   +1 more source

Spatial multi‐omics unveils sphingolipid metabolic reprogramming within the retinal pathological niche

iMeta, EarlyView.
Spatial multi‐omics of the mouse ocular globe after retinal ischemia‐reperfusion (RIR) injury identifies the ganglion cell layer (GCL) as an immunometabolic niche where Trem2+ microglia closely associate with stressed retinal ganglion cells (RGCs) through Trem2‐Apoe signaling.
Yunhong Shi, Jinpei Lin, Yi Wu, Shengsong Xu, Naiyuan Zhang, Yiji Pan, Anli Ren, Ying Fang, Yu Huang, Xiayin Zhang, Zhuoting Zhu, Yehong Zhuo, Honghua Yu   +12 more
wiley   +1 more source

Three-Decade Evaluation of Cerebrospinal Fluid Pressure in Open-Angle Glaucoma at a Tertiary Care Center

Journal of Ophthalmology, 2020
Elevated intraocular pressure (IOP) is the most prevalent risk factor for primary open-angle glaucoma. However, IOP alone does not fully describe a mechanical basis for disease in patients with normal tension glaucoma or primary open-angle glaucoma.
Catherine G. Knier, David Fleischman, David O. Hodge, John P. Berdahl, Michael P. Fautsch   +4 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Primary open angle glaucoma and hypothyroidism

Clinical Optometry, 2010
George Kitsos1, Chrisavgi Pappa1, Agathoklis Tsatsoulis21Department of Ophthalmology, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece; 2Endocrinology Clinic, Department of Internal Medicine, Medical School ...
George Kitsos, Chrisavgi Pappa, Agathoklis Tsatsoulis   +2 more
doaj  

Tear and aqueous humour cytokine profile in primary open-angle glaucoma.

Acta ophthalmologica, 2020
PURPOSE To evaluate the concentrations of pro-inflammatory cytokines in tear and aqueous humour of patients with primary open-angle glaucoma (POAG), relative to healthy controls.
B. Burgos-Blasco, B. Vidal-Villegas, F. Saénz-Francés, L. Morales-Fernández, L. Perucho‐González, J. García-Feijóo, J. Martínez-de-la-Casa   +6 more
semanticscholar   +1 more source

Optic Nerve Thickness Assessed by Ocular Ultrasonography in Obstructive Sleep Apnea

Journal of Ultrasound in Medicine, EarlyView.
Objectives Obstructive sleep apnea (OSA) has been associated with various ocular complications, yet ultrasonographic evaluation of optic nerve thickness and its relationship with nocturnal hypoxemia remains poorly understood. This study aimed to evaluate optic nerve thickness and globe dimensions using ocular ultrasonography in patients with different ...
Buğra Kerget, Eyüp Çetin, Alperen Aksakal, Sırma Merve Çetin, Mustafa Buğra Coşkuner   +4 more
wiley   +1 more source

An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity.

Ophthalmology (Rochester, Minn.), 2020
PURPOSE To examine the combined effects of common genetic variants associated with intraocular pressure (IOP) on primary open-angle glaucoma (POAG) phenotype using a polygenic risk score (PRS) stratification.
Ayub Qassim, E. Souzeau, O. Siggs, Mark M. Hassall, Xikun Han, H. Griffiths, N. Frost, N. Vallabh, J. Kirwan, G. Menon, A. Cree, A. Galanopoulos, A. Agar, P. Healey, S. Graham, J. Landers, R. Casson, P. Gharahkhani, C. Willoughby, A. Hewitt, A. Lotery, S. Macgregor, J. Craig   +22 more
semanticscholar   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source