Results 151 to 160 of about 4,572,451 (270)

Primary ovarian insufficiency and Turner syndrome

Primary Ovarian Insufficiency (POI) is characterized by oligomenorrhea/amenorrhea lasting 4 or more months, along with elevated FSH levels exceeding 25 IU/L on two occasions, one month apart, prior to age 40.
Kastury, Rama D, Dowlut-McElroy, Tazim
core   +1 more source

Nanomotor-Driven Extracellular Vesicles With Effective Tissue Penetration for Targeted Therapy of Primary Ovarian Insufficiency. [PDF]

J Extracell Vesicles
Mu Y, Wu J, Lv M, Zhang X, Song Y, Ai J, Ma D, Li K.   +7 more
europepmc   +1 more source

From prevalence to precision: Integrating phenotype, symptoms, reproductive goals, and treatment in leiomyoma care

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Uterine fibroids (leiomyomas) are present in most women during their reproductive years, yet only a subset becomes clinically meaningful. This disparity poses a central clinical challenge: distinguishing symptoms caused by fibroids from those unrelated to them.
Malcolm G. Munro
wiley   +1 more source

Wubie Fanchun Formula-inducible metabolites in primary ovarian insufficiency model mice that facilitate ovarian renovation. [PDF]

Pharm Biol
Chen Y, Chen S, Song B, Xia X, Zhang K, Chen L, Chi L, Wang Q.   +7 more
europepmc   +1 more source

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue, Tianyi Chen, Yuxiao Wu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang, Junjun Yang   +8 more
wiley   +1 more source

miR-379-5p promotes ovarian granulosa cell apoptosis in primary ovarian insufficiency by targeting KNDC1 and PEG10. [PDF]

Front Genet
Luo J, Zhang F, Feng Y, You F, Yang D, Wu Z, Zeng L.   +6 more
europepmc   +1 more source

Building families—Implementing balanced sexual and reproductive health

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract One of the main initiatives of the World Health Organization (WHO) is the promotion of Sexual and Reproductive Health (SRH). Sexuality, infertility, and contraception are three interconnected pillars of SRH, each essential for achieving global equity in family planning and family building.
Peter Y. Liu, Edgar Mocanu, Linda Giudice, Marcos Horton, Meletios P. Nigdelis, Antti Perheentupa, Andrea Sansone, Giovanni Corona, Luca Gianaroli, Dimitrios G. Goulis   +9 more
wiley   +1 more source

Diagnostic accuracy of AMH for primary ovarian insufficiency/premature ovarian failure: a real-world cohort study. [PDF]

Front Endocrinol (Lausanne)
Mao S, Yang D, Wang X, Cao X.
europepmc   +1 more source

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

iMetaMed, EarlyView.
A pan‐cancer atlas deciphers tumor‐induced reprogramming in bone metastases. Malignant evolution toward MYC/proliferation is a hallmark of bone metastases. Niche‐mediated immune dysfunction is characterized by immature pDCs, impaired antigen presentation and phagocytosis in TAMs, and exhausted T cells.
Yitong Pan, Zhou Yang, Junyuan Deng, Feng Liu, Guang Lei   +4 more
wiley   +1 more source

MCM8 variants in two patients with primary ovarian insufficiency: clinical findings and <i>in vitro</i> defective DNA repair revealed by an MCM8 double-mutant construct. [PDF]

Front Endocrinol (Lausanne)
Wang F, Zang S, Li P, Yin X.
europepmc   +1 more source