Results 201 to 210 of about 6,488,856 (287)

Antiresorptive therapy influence on peri‐implant diseases: Clinical implications and osteoimmunological perspectives

open access: yesPeriodontology 2000, EarlyView.
Abstract Background/Aim Antiresorptive therapy represents a cornerstone in the management of osteoporosis and cancer‐related bone disease through suppression of osteoclast‐mediated bone resorption. As implant therapy becomes more common in aging populations, clinicians increasingly encounter patients receiving these medications, thus making their ...
Emilio A. Cafferata   +2 more
wiley   +1 more source

CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS) in 2026. [PDF]

open access: yesCardiovasc Interv Ther
Ozaki Y   +50 more
europepmc   +1 more source

Systemic pirfenidone treatment fails to mitigate fibrosis and compromises functional recovery in a porcine model of volumetric muscle loss

open access: yesExperimental Physiology, EarlyView.
Abstract Repurposing clinically approved antifibrotic agents presents a potential near‐term therapeutic strategy to mitigate the extensive fibrotic scarring that follows severe volumetric muscle loss (VML) injury and inhibits functional recovery. We hypothesized that daily oral administration of pirfenidone, an FDA‐approved antifibrotic, would mitigate
Jessica M. Motherwell   +4 more
wiley   +1 more source

Running‐based rehabilitation does not improve muscle function after volumetric muscle loss despite improving hindlimb weight‐bearing asymmetry in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Volumetric muscle loss (VML) is a traumatic skeletal muscle injury characterized by chronic functional impairments in the affected muscle and adjacent uninjured bone. Rehabilitative strategies aimed at restoring limb function following VML, including voluntary running, have shown limited efficacy and in some cases have been detrimental.
Angela S. Bruzina   +5 more
wiley   +1 more source

Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction. [PDF]

open access: yesOpen Heart
Laffan J   +14 more
europepmc   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat   +6 more
wiley   +1 more source

Missing-data-aware machine learning prediction of in-hospital major adverse cardiovascular events after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. [PDF]

open access: yesSci Rep
Mirzohreh ST   +10 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

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