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Bivalirudin versus heparin with primary percutaneous coronary intervention
American Heart Journal, 2018Optimal adjunctive therapy in ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI (PPCI) remains a matter of debate. Our aim was to compare the efficacy and safety of bivalirudin to unfractionated heparin (UFH), with or without glycoprotein IIb/IIIa inhibitors (GPI) in a large real-world population, using data from the ...
Dimitrios, Venetsanos +6 more
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Contrast-induced nephropathy in primary percutaneous coronary intervention
Heart, 2011It is clear that the development of contrast-induced nephropathy (CIN) is both common and prognostically important in patients undergoing interventional cardiovascular procedures. CIN is now established as the third most common cause of hospital-acquired acute kidney injury (after surgery and hypotension).1 The expansion in the use of iodinated ...
Sean, Gallagher, Charles, Knight
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The role of fibrinolysis in the era of primary percutaneous coronary intervention
Thrombosis and Haemostasis, 2011Most cases of acute myocardial infarction are caused by disruption of an atherosclerotic plaque followed by coronary thrombosis (1). In ST-elevation myocardial infarction (STEMI), the thrombus occludes a major epicardial coronary artery. Such an occlusion is an emergency situation, and flow in the occluded vessel should be restored as fast as possible.
Sigrun, Halvorsen, Kurt, Huber
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Transient no reflow following primary percutaneous coronary intervention
Heart and Vessels, 2013No reflow following primary percutaneous coronary intervention (PCI) is a serious complication in the treatment of acute myocardial infarction. No reflow in some patients is reversible (transient no reflow), whereas no reflow in others persists until the end of the procedure (persistent no reflow).
Hiroyuki, Jinnouchi +8 more
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Primary Percutaneous Coronary Intervention for All?
JAMA, 2002the number of trials and number of patients randomized has more than doubled to 21 trials and 6800 patients, all of which show clear benefit of PCI over thrombolysis. A metaanalysis of the randomized trials carried out through 1997 showed a clear reduction in mortality, recurrent MI, stroke, and intracranial hemorrhage. Mortality was reduced a relative
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Primary Percutaneous Coronary Intervention
2010Thomas Pilgrim, Stephan Windecker
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