Results 141 to 150 of about 3,071,873 (306)

What do dentists do and earn? An exploratory analysis of French dentists with a focus on primary care teams

BMC Primary Care
Access to dental care in France faces two main barriers: high out-of-pocket costs and a widely uneven distribution of dentists. Multiprofessional primary care groups (MPCGs) are currently in development to improve primary care efficiency and enhance the ...
Anne-Charlotte Bas, Matthieu Cassou, Carine Franc   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Health and the primary prevention of violence against women [PDF]

This position paper focuses on the primary prevention of violence perpetrated by men against women. It develops a position on primary prevention (as distinct from secondary and tertiary interventions).

core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Obstructive sleep apnea and the severity of coronary artery disease

Caspian Journal of Internal Medicine, 2018
Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension.
Ali Vasheghani-Farahani, Fatemeh Kazemnejad, Khosro Sadeghniiat-Haghighi, Soleil Saadat, Parya Tavakoli poor, Tahereh Yazdani, Mohammad Alidoosti, Vahid Ghasem Amooeian, Haleh Ashraf   +8 more
doaj  

Protocol for sampling multidrug-resistant bacteria using artificial plastic substrates in aquatic ecosystems

STAR Protocols
Summary: Artificial plastic substrates (APSs) consist of four plastic polymers that work as traps for pathogenic bacteria and facilitate their sampling and detection.
Ifra Ferheen, Roberto Spurio, Stefania Marchggiani   +2 more
doaj   +1 more source

Primary Prevention

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
openaire   +2 more sources

Methods and approaches to improving the emotional health and well being of children: A briefing paper concerning interventions to prevent internalising disorders [PDF]

, 2008
This paper presents a summary of the prevalence of somatic, anxiety and depressive disorders in children and of the known risk and protective factors associated with these problems.
Smith, Marjorie, Storey, Pamela
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source