Results 121 to 130 of about 7,096,949 (304)

Putting Your Health in Your Own Hands: A New Strategy for Primary Stroke Prevention

open access: yes, 2015
As evidenced by the increasing stroke burden worldwide, currently used primary stroke prevention strategies are not effective enough. One of the main reasons for insufficient effectiveness of the currently used primary stroke prevention strategies are ...
Krishnamurthi, R   +2 more
core  

A review of skin cancer primary prevention activities in primary care settings

open access: yes
Objectives: Skin cancer is highly preventable through primary prevention activities such as avoiding ultraviolet radiation exposure during peak times and regular use of sun protection.
Amelia K Smit   +15 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Aspirin overutilization for the primary prevention of cardiovascular disease

open access: yes, 2014
Jeffrey J VanWormer,1 Aaron W Miller,2 Shereif H Rezkalla3 1Center for Clinical Epidemiology and Population Health, 2Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, WI, USA; 3Department of Cardiology, Marshfield
Rezkalla SH, Miller AW, VanWormer JJ
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

What do dentists do and earn? An exploratory analysis of French dentists with a focus on primary care teams

open access: yesBMC Primary Care
Access to dental care in France faces two main barriers: high out-of-pocket costs and a widely uneven distribution of dentists. Multiprofessional primary care groups (MPCGs) are currently in development to improve primary care efficiency and enhance the ...
Anne-Charlotte Bas   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Evidence informed practice in Primary Education: an unintended but valuable resource

open access: yes, 2009
This considers the potential of the Teacher Training Resource Bank (TTRB) as a resource for professional development with primary education. Although, the portal was designed with the needs of Teacher Education in mind, the resource has been evaluated as
Blamires, M.   +1 more
core  

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