Results 111 to 120 of about 3,071,873 (306)

Safety of medication use in primary care [PDF]

, 2015
© 2014 Royal Pharmaceutical Society.BACKGROUND: Medication errors are one of the leading causes of harmin health care. Review and analysis of errors have often emphasized their preventable nature and potential for reoccurrence.
Abramson, Abramson, Adubofour, Ahmad, Al Khaja, Al Khaja, Alldred, Alldred, Aronson, Aronson, Ashcroft, Avery, Avery, Avery, Barber, Bayoumi, Berner, Bernstein, Beso, Boockvar, Boockvar, Booij, Braund, Bregnhoj, Britt, Brown, Buurma, Campbell, Carruthers, Chen, Chua, Coleman, Dallenbach, Dean, Dean, Dean, Dean Franklin, Dean Franklin, Department of Health, Department of Health, Department of Health, Devine, Dhabali, Eslami, Field, Fischer, Flynn, Gagne, Gandhi, Gandhi, Gandhi, Garfield, Ghaleb, Ginzburg, Glassman, Green, Gurwitz, Hazlet, Howard, Hume, Humphries, Hämmerlein, Janice O. Olaniyan, Kaushal, Kaushal, Kennedy, Khoja, Knudsen, Knudsen, Kohn, Kuo, Lafata, Lasser, Leape, Lemer, Lewis, Lisby, Lopez-Picazo, Lynskey, Maisoon Ghaleb, Martínez Sánchez, Marwaha, Miller, Moniz, Nanji, Nemeth, Norden-Hagg, Palen, Paul Robinson, Pirmohamed, Raebel, Reason, Royal, Runciman, Sarvadikar, Sayers, Shah, Singh, Soraya Dhillon, Sorensen, Stefanovic, Sweidan, Szczepura, Tam, Tamblyn, Teinilä, Thomsen, Varkey, Vincent, Warholak, Wetzels, Wild, Wong, World Health Organisation   +113 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Four-year long-term follow-up of diabetes patients after implementation of the Chronic Care Model in primary care: a cross-sectional study

Swiss Medical Weekly, 2017
AIMS Implementing the Chronic Care Model (CCM) via involvement of specially trained practice nurses improves cardiovascular risk profiles and perception of care among type 2 diabetes patients in small primary care practices (PCPs) in the ...
Corinne Chmiel, Irina Giewer, Anja Frei, Thomas Rosemann   +3 more
doaj   +1 more source

Mainstreaming prevention: Prescribing fruit and vegetables as a brief intervention in primary care [PDF]

, 2005
This is the author's PDF version of an article published in Public health© 2005.This articles discusses a project at the Castlefields Health Centre in Halton whereby primary care professionals issue a prescription for discounts on fruit and vegetables ...
Appel, B. Ellahi, Butland, C. Bradbury, Forastiere, John, Joshipura, M. Hodgson, M. Kearney, M. Thurston, Mainous, Ness, Sargeant, Taylor   +13 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

E-cigarettes – their use and harmfulness. A brief summary of current scientific knowledge

Nowotwory
The consumption of e-cigarettes has rapidly increased in the last years, both worldwide and in Poland, especially among adolescents and youth. Many e-cigarette users also smoke conventional cigarettes (“dual use”). Some researchers argue that e-cigarette
Krzysztof Przewoźniak, Paweł Koczkodaj
doaj   +1 more source

Role of Implantable Cardioverter Defibrillators in the Treatment of Hypertrophic Cardiomyopathy [PDF]

, 2005
Hypertrophic cardiomyopathy (HCM) is an important cardiovascular disease with sudden cardiac death as the most devastating presentation. Implantable cardioverter defibrillators (ICD) are the optimal therapy for prevention of sudden death from ventricular
Ghosh, Joydeep, Francis, Johnson, Maron, Barry J.   +2 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Targeting Adults for Supplementary Immunization Activities of Measles Control in Central China: A Mathematical Modelling Study

Scientific Reports, 2018
Routine immunizations and supplementary immunization activities (SIAs) have significantly improved measles control over the past two decades in China. Progress towards eliminating measles currently faces multiple challenges as the infection age increases,
Ka Chun Chong, Chi Zhang, Katherine Min Jia, Benny Chung Ying Zee, Tongyong Luo, Lei Wang, Greta Chun Huen Tam, Riyang Sun, Maggie Haitian Wang, Xuhua Guan   +9 more
doaj   +1 more source