Results 91 to 100 of about 3,071,873 (306)

Early administration of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in patients with acute coronary syndrome: a systematic review and meta-analysis

BMC Cardiovascular Disorders
Background High-intensity statin therapy is currently recommended initial guideline therapy in ACS treatment. However, only a minority of patients are achieving LDL-C attainment goal at 6 months.
Kaveh Hosseini, Hamidreza Soleimani, Saba Maleki, Amir Nasrollahizadeh, Sima Tayebi, John Nelson, Sean P. Heffron   +6 more
doaj   +1 more source

Adolescent Health Services: Missing Opportunities [PDF]

, 2008
Examines the status of adolescents' health and health services, including critical needs, promising models, and components for improving disease prevention and health promotion.
Jennifer Appleton Gootman, Leslie J. Sim, Robert S. Lawrence   +2 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A multi-stage approach to support timely health policy decisions during crisis: the fast-track Delphi

BMC Public Health
Background Scientists can play an important role in policymaking by providing evidence and consensual expert opinion on the state of scientific knowledge.
Camille Velarde Crézé, Olivier Duperrex, Luc Lebon, Vincent Faivre, Myriam Pasche, Jacques Cornuz   +5 more
doaj   +1 more source

Integrating smoking cessation counseling into oncology practice — benefits and barriers

Nowotwory
Exposure to tobacco smoke, which contains around 70 carcinogenic components, leads to approximately 8 million deaths worldwide annually. Poland ranks among the top countries with the highest tobacco-related DALY (Disability-Adjusted Life Years) rates ...
Magdalena Cedzyńska, Irena A. Przepiórka   +1 more
doaj   +1 more source

Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders

eLife, 2014
Recent studies suggest de novo mutations may involve the pathogenesis of autism and attention-deficit/hyperactivity disorder (ADHD). Based on the evidence that excessive alcohol consumption may be associated with an increased rate of de novo mutations in
Jan Sundquist, Kristina Sundquist, Jianguang Ji   +2 more
doaj   +1 more source

Caesarean delivery in a migration context: the role of prior delivery in the host country

Sexual and Reproductive Health Matters, 2020
Migrant women in industrialised countries experience high caesarean section (CS) rates but little is known about the effect of a previous delivery in the host country.
Lorraine Poncet, Henri Panjo, Armelle Andro, Virginie Ringa   +3 more
doaj   +1 more source

Shared decision-making about cardiovascular disease medication in older people: A qualitative study of patient experiences in general practice [PDF]

, 2019
Objectives To explore older people's perspectives and experiences with shared decision-making (SDM) about medication for cardiovascular disease (CVD) prevention.
Bonner, Carissa, Doust, Jenny, Jansen, Jesse, McCaffery, Kirsten, McKinn, Shannon, Muscat, Danielle Marie   +5 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Epidemiology of substance and opium use among adult residents of Tehran; a comprehensive report from Tehran cohort study (TeCS)

BMC Psychiatry
Background The prevalence and burden of substance and opium use have increased worldwide over the past decades. In light of rapid population changes in Tehran, we aimed to evaluate the prevalence of opium and other substance use among adult residents in ...
Farzad Masoudkabir, Akbar Shafiee, Amirhossein Heidari, Negin Sadat Hosseini Mohammadi, Kiarash Tavakoli, Arash Jalali, Sepehr Nayebirad, Farshid Alaeddini, Soheil Saadat, Ali Vasheghani-Farahani, Saeed Sadeghian, Vicente Artola Arita, Mohamamdali Boroumand, Abbasali Karimi   +13 more
doaj   +1 more source