Results 41 to 50 of about 7,735,427 (345)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Childhood Leukemia and Primary Prevention [PDF]

Current Problems in Pediatric and Adolescent Health Care, 2016
Leukemia is the most common pediatric cancer, affecting 3800 children per year in the United States. Its annual incidence has increased over the last decades, especially among Latinos. Although most children diagnosed with leukemia are now cured, many suffer long-term complications, and primary prevention efforts are urgently needed. The early onset of
Catherine Metayer, Joseph L. Wiemels, Joseph L. Wiemels, Amanda W. Singer, Todd P. Whitehead, Mark D. Miller, Mark D. Miller   +6 more
openaire   +4 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Triglyceride-glucose index as a predictor of cardiac adverse events in acute coronary syndrome patients undergoing percutaneous coronary intervention: role of diabetes

BMC Cardiovascular Disorders
Background Triglyceride-glucose index (TyG), a surrogate marker of insulin resistance (IR), could be a potential prognostic marker in patients with acute coronary syndromes (ACS).
Amirmohammad Khalaji, Amir Hossein Behnoush, Yeganeh Pasebani, Ali Rafati, Tara Mahmoodi, Alireza Arzhangzadeh, Sima Shamshiri Khamene, Izat MohammadKhawajah, Mehdi Mehrani, Ali Vasheghani-Farahani, Farzad Masoudkabir, Kimia Najafi, Mani K. Askari, Anil Harrison, John R. Nelson, Kaveh Hosseini, Adrian V. Hernandez   +16 more
doaj   +1 more source

Epidemiological changes in measles infections in southern China between 2009 and 2016: a retrospective database analysis

BMC Infectious Diseases, 2020
Background The incidence rate of measles in China reached a nadir in 2012 after 2 supplementary immunization activities (SIAs) were undertaken in 2009 and 2010.
Huizhen Zheng, Katherine Min Jia, Riyang Sun, Pui Hu, Maggie Haitian Wang, Benny Chung-Ying Zee, Wenjia Liang, Ka Chun Chong   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

HPV vaccination coverage in the European Region

Nowotwory
Introduction.The human papillomavirus (HPV) is an established cause of cervical cancer and other HPV-related dise­ases. This study aims to analyze the variation in coverage by HPV vaccination programs – particularly within European Region countries – and
Mariola Borowska, Paweł Koczkodaj, Marta Mańczuk   +2 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Frailty efficacy as a predictor of clinical and cognitive complications in patients undergoing coronary artery bypass grafting: a prospective cohort study

BMC Cardiovascular Disorders
Background Frailty is proposed as a predictor of outcomes in patients undergoing major surgeries, although data on the association of frailty and coronary artery bypass grafting (CABG) are lacking.
Mehrnoosh Bakhtiari, Farhad Shaker, Fatemeh Ojaghi Shirmard, Arash Jalali, Ahmad Vakili-Basir, Mohammad Balabandian, Sima Shamshiri Khamene, Izat Mohammadkhawajah, Akbar Shafiee, Seyedeh Zahra Badrkhahan, Kaveh Hosseini   +10 more
doaj   +1 more source