Results 61 to 70 of about 8,411,226 (265)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Evidence informed practice in Primary Education: an unintended but valuable resource

open access: yes, 2009
This considers the potential of the Teacher Training Resource Bank (TTRB) as a resource for professional development with primary education. Although, the portal was designed with the needs of Teacher Education in mind, the resource has been evaluated as
Blamires, M.   +1 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Energy Effectiveness Of Crops In Crop Rotation Under Different Soil Tillage Systems

open access: yesAgriculture, 2015
The paper identifies and compares the energy balance of winter wheat, spring barley and white mustard – all grown in crop rotation under different tillage conditions. The field trial included the conventional tillage (CT) method, minimum tillage (MT) and
Strašil Zdeněk   +2 more
doaj   +1 more source

A novel approach to product lifecycle management and engineering using behavioural models for the conceptual design phase.

open access: yes
This work builds upon a previous proposal for the use of the extended SAPPhIRE model of causality as a foundation for a PLM system, and more specifically the management of design data at the conceptual design phase.

core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Analisis PDRB sektor primer dan kesempatan kerja di Kabupaten Bungo

open access: yesJurnal Perspektif Pembiayaan dan Pembangunan Daerah, 2013
This study aims to see the development of value-added primary sector and sub sectors of primary, value-added contribution of primary sector and sub sectors of GDP primary Bungo district, the elasticity of value added of primary sector and sub sector of ...
Anis Mayanti, Syaparuddin, Erni Achmad
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Parkside Primary School PTA letter

open access: yes, 1996
Letter to parents of a resolution taken at a meeting of the Parkside Primary School PTA, held at the Muslim Movement Hall, to oppose the department's envisaged rationalisation ...
Parent Teacher Assocation, Parkside Primary School
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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