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Primary progressive aphasia [PDF]
Scandinavian Journal of Psychology, 2014 Primary progressive aphasia (PPA) is a progressive loss of specific language functions with relative sparing of other cognitive domains at least for the first few years of the illness. Based on the constellation of symptoms, PPA has been recently classified into a nonfluent, semantic, or logopenic variant.
Andrew, Kertesz, Michał, Harciarek
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Familial Primary Progressive Aphasia
Alzheimer Disease & Associated Disorders, 2003Primary progressive aphasia (PPA) is a neurodegenerative disease presenting with isolated, progressive, language dysfunction. After at least 2 years, dementia may develop, but the aphasia predominates. Few families with hereditary PPA have been reported; some have autosomal dominance. A chromosome 17 mutation in tau exon 13 has been found in one family,
Thomas A, Krefft +4 more
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Annals of Neurology, 2001
AbstractPrimary progressive aphasia (PPA) is a focal dementia characterized by an isolated and gradual dissolution of language function. The disease starts with word‐finding disturbances (anomia) and frequently proceeds to impair the grammatical structure (syntax) and comprehension (semantics) of language.
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AbstractPrimary progressive aphasia (PPA) is a focal dementia characterized by an isolated and gradual dissolution of language function. The disease starts with word‐finding disturbances (anomia) and frequently proceeds to impair the grammatical structure (syntax) and comprehension (semantics) of language.
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Primary progressive aphasia presenting as conduction aphasia
Journal of the Neurological Sciences, 1999We report a case of a woman with primary progressive aphasia (PPA) who presented with conduction aphasia. A 60-year-old, right-handed, Japanese female suffering from progressive aphasia had difficulty in repeating words and phrases. She displayed phonemic paraphasias but had preserved comprehension and had no cognitive or behavior disorder for more ...
K, Hachisuka +4 more
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Aphasiology, 1992
Abstract In recent years there has been increasing interest in individuals with gradual deterioration of language skills in the absence of generalized cognitive impairments or identifiable vascular, neoplastic, metabolic, or infectious aetiology. In this paper, we review the available data on primary progressive aphasia and summarize the demographic ...
Joseph R. Duffy, Ronald C. Petersen
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Abstract In recent years there has been increasing interest in individuals with gradual deterioration of language skills in the absence of generalized cognitive impairments or identifiable vascular, neoplastic, metabolic, or infectious aetiology. In this paper, we review the available data on primary progressive aphasia and summarize the demographic ...
Joseph R. Duffy, Ronald C. Petersen
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Neurology, 2010
When a patient presents with acute aphasia, today's neurologist takes swift action to characterize the clinical syndrome and use neuroimaging and other tools to identify its pathophysiologic basis. One goal of these urgent efforts is to determine whether the patient has an ischemic process that merits thrombolytic intervention.
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When a patient presents with acute aphasia, today's neurologist takes swift action to characterize the clinical syndrome and use neuroimaging and other tools to identify its pathophysiologic basis. One goal of these urgent efforts is to determine whether the patient has an ischemic process that merits thrombolytic intervention.
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Imaging in primary progressive aphasia
Neuroradiology, 1997Primary progressive aphasia (PPA) presents with aphasia, with or without other minor cognitive dysfunction. We report five patients with PPA to show the correlation between their clinical signs and imaging findings. The patients can be divided into those with nonfluent (group 1) and those with fluent (group 2) aphasia.
K, Abe, H, Ukita, T, Yanagihara
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Clinical neuroscience (New York, N.Y.), 1997
Primary progressive aphasia is an important recently emphasized clinical syndrome that is a common early manifestation of Pick's disease and Pick complex pathology. It is defined clinically as slowly progressive language disturbance that remains relatively isolated from other cognitive or behavioral deficits for at least 2 years.
A, Kertesz, D G, Munoz
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Primary progressive aphasia is an important recently emphasized clinical syndrome that is a common early manifestation of Pick's disease and Pick complex pathology. It is defined clinically as slowly progressive language disturbance that remains relatively isolated from other cognitive or behavioral deficits for at least 2 years.
A, Kertesz, D G, Munoz
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Primary Progressive Aphasia: A Review
Neurocase, 2004This review summarizes clinical and imaging features associated with primary progressive aphasia (PPA). We investigate the hypothesis that these patients can be divided into subgroups of progressive non-fluent aphasia (PNFA) and semantic dementia (SD), based on their linguistic profiles and related imaging studies, and examine whether each of these ...
Murray, Grossman, Sharon, Ash
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