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Primary progressive aphasia [PDF]

open access: possibleScandinavian Journal of Psychology, 2014
Primary progressive aphasia (PPA) is a progressive loss of specific language functions with relative sparing of other cognitive domains at least for the first few years of the illness. Based on the constellation of symptoms, PPA has been recently classified into a nonfluent, semantic, or logopenic variant.
Andrew, Kertesz, Michał, Harciarek
openaire   +4 more sources

Progress in Primary Progressive Aphasia: A Review

Cognitive and Behavioral Neurology, 2023
We present a review of the definition, classification, and epidemiology of primary progressive aphasia (PPA); an update of the taxonomy of the clinical syndrome of PPA; and recent advances in the neuroanatomy, pathology, and genetics of PPA, as well as the search for biomarkers and treatment.
Andrew, Kertesz   +2 more
openaire   +2 more sources

Imaging in primary progressive aphasia

Neuroradiology, 1997
Primary progressive aphasia (PPA) presents with aphasia, with or without other minor cognitive dysfunction. We report five patients with PPA to show the correlation between their clinical signs and imaging findings. The patients can be divided into those with nonfluent (group 1) and those with fluent (group 2) aphasia.
K, Abe, H, Ukita, T, Yanagihara
openaire   +2 more sources

Primary Progressive Aphasia: A Review

Neurocase, 2004
This review summarizes clinical and imaging features associated with primary progressive aphasia (PPA). We investigate the hypothesis that these patients can be divided into subgroups of progressive non-fluent aphasia (PNFA) and semantic dementia (SD), based on their linguistic profiles and related imaging studies, and examine whether each of these ...
Murray, Grossman, Sharon, Ash
openaire   +2 more sources

Depression in Primary Progressive Aphasia

Journal of Geriatric Psychiatry and Neurology, 2007
Primary Progressive Aphasia (PPA) is a clinical dementia syndrome in which language functions decline over time while other cognitive domains remain relatively preserved for at least 2 years. Because PPA patients suffer progressive interference with communication despite relatively preserved memory, reasoning, and insight, there is reason to believe ...
Jennifer, Medina, Sandra, Weintraub
openaire   +2 more sources

Familial Primary Progressive Aphasia

Alzheimer Disease & Associated Disorders, 2003
Primary progressive aphasia (PPA) is a neurodegenerative disease presenting with isolated, progressive, language dysfunction. After at least 2 years, dementia may develop, but the aphasia predominates. Few families with hereditary PPA have been reported; some have autosomal dominance. A chromosome 17 mutation in tau exon 13 has been found in one family,
Thomas A, Krefft   +4 more
openaire   +2 more sources

An update on primary progressive aphasia

Current Neurology and Neuroscience Reports, 2007
Primary progressive aphasia is a neurodegenerative syndrome characterized by a relentless dissolution of language but relative sparing of other cognitive domains during the initial stages of the disease. Substantial progress has been made in understanding the clinical characteristics, imaging, genetics, and neuropathology of this syndrome. This article
Emily, Rogalski, Marsel, Mesulam
openaire   +2 more sources

Swallowing in primary progressive aphasia

NeuroRehabilitation: An International, Interdisciplinary Journal, 2016
BACKGROUND: Few studies have described characteristics of swallowing in primary progressive aphasia (PPA) and its variants. OBJECTIVE: To describe and characterize swallowing and eating behaviors of patients with PPA, as well as their correlates with neuropsychiatric symptoms and patterns of communication.
Sheilla de Medeiros Correia, Marin   +6 more
openaire   +2 more sources

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