Results 1 to 10 of about 2,380 (167)

Quantitative assessment of grammar in amyloid-negative logopenic aphasia [PDF]

Brain and Language, 2018
Logopenic primary progressive aphasia (lvPPA) typically results from underlying Alzheimer's disease, but subjects have been reported that do not show beta-amyloid (Aβ) deposition. These subjects do not differ on neurological and speech-language testing from Aβ-positive lvPPA, but they impressionistically show increased grammatical deficits.
Katerina A Tetzloff, Jennifer L Whitwell, René L Utianski   +2 more
exaly   +5 more sources

Empathy in primary progressive aphasia: Neural signatures and longitudinal trajectories. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Empathy is increasingly recognised as compromised in neurodegenerative disorders. However, its profile and neural bases in the nonfluent (nfvPPA) and logopenic (lvPPA) variants of primary progressive aphasia remain unclear. We aimed to characterize empathy at onset, examine its longitudinal course, and identify neural correlates ...
Cordonier N, Matis S, Teng H, Carrick J, Hwang Y, Ahmed RM, Landin-Romero R, Piguet O.   +7 more
europepmc   +2 more sources

Logopenic progressive aphasia with neologisms: a case report [PDF]

BMC Neurology, 2019
Background Neologisms are commonly encountered in patients with acute cerebrovascular diseases, particularly in those with Wernicke’s aphasia. However, few studies have investigated primary progressive aphasia with neologisms in neurodegenerative disease.
Hiroyuki Watanabe, Manabu Ikeda, Etsuro Mori   +2 more
doaj   +3 more sources

Identification of an atypical variant of logopenic progressive aphasia [PDF]

Brain and Language, 2013
The purpose of this study was to examine the association between aphasia severity and neurocognitive function, disease duration and temporoparietal atrophy in 21 individuals with the logopenic variant of primary progressive aphasia (lvPPA). We found significant correlations between aphasia severity and degree of neurocognitive impairment as well as ...
Mary M Machulda, Jennifer L Whitwell, Joseph R Duffy   +2 more
exaly   +3 more sources

Impaired phonemic discrimination in logopenic variant primary progressive aphasia [PDF]

Annals of Clinical and Translational Neurology, 2020
Logopenic variant primary progressive aphasia (lvPPA) is the least well defined of the major primary progressive aphasia (PPA) syndromes. We assessed phoneme discrimination in patients with PPA (semantic, nonfluent/agrammatic, and logopenic variants) and
Jeremy C. S. Johnson, Jessica Jiang, Rebecca L. Bond, Elia Benhamou, Maï‐Carmen Requena‐Komuro, Lucy L. Russell, Caroline Greaves, Annabel Nelson, Harri Sivasathiaseelan, Charles R. Marshall, Anna P. Volkmer, Jonathan D. Rohrer, Jason D. Warren, Chris J. D. Hardy   +13 more
doaj   +4 more sources

Non-verbal dichotic listening: A new cognitive hearing test for dementia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Central hearing difficulties are a feature of Alzheimer's disease (AD) but not well captured by standard speech perception tests. METHODS We developed a non‐verbal dichotic listening test (NVDLT) based on everyday sounds, and compared this with a standard verbal dichotic listening test (VDLT) in 36 people with primary progressive ...
Hardy CJD, Levett BA, Jiang J, Core LB, Froud S, Bishop L, Lim D, Durrani F, Volkmer A, Koohi N, Bamiou DE, Marshall CR, Warren JD.   +12 more
europepmc   +2 more sources

Logopenic aphasia or Alzheimer's disease: Different phases of the same disease? [PDF]

Dementia & Neuropsychologia, 2014
The logopenic variant of Primary Progressive Aphasia, or logopenic aphasia, is a the most recently described variant of Primary Progressive Aphasia and also the least well defined.
Bárbara Costa Beber, Renata Kochhann, Bruna Matias da Silva, Marcia L. F. Chaves   +3 more
doaj   +4 more sources

Degenerative Jargon Aphasia: Unusual Progression of Logopenic/Phonological Progressive Aphasia?

Behavioural Neurology, 2013
Primary progressive aphasia (PPA) corresponds to the gradual degeneration of language which can occur as nonfluent/agrammatic PPA, semantic variant PPA or logopenic variant PPA.
Paolo Caffarra, Simona Gardini, Stefano Cappa, Francesca Dieci, Letizia Concari, Federica Barocco, Caterina Ghetti, Livia Ruffini, Guido Dalla Rosa Prati   +8 more
doaj   +3 more sources

Patterns of Neuropsychological Dysfunction and Cortical Volume Changes in Logopenic Aphasia. [PDF]

J Alzheimers Dis, 2018
Background: Neuropsychological assessment can add essential information to the characterization of individuals presenting with the logopenic variant of primary progressive aphasia (lvPPA). Objective: This study examined the ...
Owens TE, Machulda MM, Duffy JR, Strand EA, Clark HM, Boland S, Martin PR, Lowe VJ, Jack CR, Whitwell JL, Josephs KA.   +10 more
europepmc   +4 more sources

Automated item-level measures of verbal fluency in semantic and logopenic primary progressive aphasia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Verbal fluency tasks are widely used in primary progressive aphasia (PPA), but most studies rely only on total correct responses, overlooking qualitative features of the words produced. We applied a scalable computational framework to extract item‐level features from fluency responses in semantic variant (svPPA) and logopenic ...
Vonk JMJ, Ferrante FJ, Morin BT, Rodriguez DA, Lin M, Bogley R, de Leon J, Tee BL, Santos-Santos MÁ, Miller ZA, Mandelli ML, Gorno-Tempini ML, García AM.   +12 more
europepmc   +2 more sources