Results 1 to 10 of about 34,580 (193)

Quantitative assessment of grammar in amyloid-negative logopenic aphasia [PDF]

Brain and Language, 2018
Logopenic primary progressive aphasia (lvPPA) typically results from underlying Alzheimer's disease, but subjects have been reported that do not show beta-amyloid (Aβ) deposition. These subjects do not differ on neurological and speech-language testing from Aβ-positive lvPPA, but they impressionistically show increased grammatical deficits.
Jennifer L Whitwell, Joseph R Duffy, Rene Utianski   +2 more
exaly   +5 more sources

FDG PET and MRI in logopenic primary progressive aphasia versus dementia of the Alzheimer's type. [PDF]

PLoS ONE, 2013
The logopenic variant of primary progressive aphasia is an atypical clinical variant of Alzheimer's disease which is typically characterized by left temporoparietal atrophy on magnetic resonance imaging and hypometabolism on F-18 fluorodeoxyglucose ...
Ajay Madhavan, Jennifer L Whitwell, Stephen D Weigand, Joseph R Duffy, Edythe A Strand, Mary M Machulda, Nirubol Tosakulwong, Matthew L Senjem, Jeffrey L Gunter, Val J Lowe, Ronald C Petersen, Clifford R Jack, Keith A Josephs   +12 more
doaj   +2 more sources

Speech-In-Noise Perception in Alzheimer's Disease and Primary Progressive Aphasia. [PDF]

Eur J Neurol
Speech‐in‐noise perception is impaired in Alzheimer's disease and primary progressive aphasia when accounting for peripheral hearing and general cognitive functions, and is associated with grey matter volume in the right supramarginal gyrus. ABSTRACT Background Understanding speech despite background noise is essential for everyday communication, but ...
Froud SA, Levett BA, Jiang J, Core LB, Koohi N, Tutton M, Green T, Bamiou DE, Marshall CR, Hardy CJD, Warren JD.   +10 more
europepmc   +2 more sources

The Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale in frontotemporal dementia and Alzheimer's disease. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Sleep disturbance is common in dementia, impacting daytime function and care. Compared with Alzheimer's disease (AD), sleep in frontotemporal dementia (FTD) is poorly characterized. METHODS We assessed sleep using the Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index in 58 people with primary progressive aphasia (PPA ...
Jiang J, Larsen EK, Levett BA, Core LB, Froud SA, Della Monica C, Hassanin H, Atzori G, Hardy CJ, Busche MA, Dijk DJ, Revell VL, Harris SS, Eriksson SH, Warren JD.   +14 more
europepmc   +2 more sources

Empathy in primary progressive aphasia: Neural signatures and longitudinal trajectories. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Empathy is increasingly recognised as compromised in neurodegenerative disorders. However, its profile and neural bases in the nonfluent (nfvPPA) and logopenic (lvPPA) variants of primary progressive aphasia remain unclear. We aimed to characterize empathy at onset, examine its longitudinal course, and identify neural correlates ...
Cordonier N, Matis S, Teng H, Carrick J, Hwang Y, Ahmed RM, Landin-Romero R, Piguet O.   +7 more
europepmc   +2 more sources

Neuropathology-specific language features in primary progressive aphasia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Primary Progressive Aphasia (PPA) clinical syndromes do not align consistently with underlying pathology. This study aimed to identify language markers for specific neuropathologies using both standard clinical tests and narrative speech analysis.
Stocks J, Barbieri E, Los MA, Thompson CK, Gefen T, Geula C, Mesulam MM, Weintraub S.   +7 more
europepmc   +2 more sources

Better Conversations Communication Partner Training for Progressive and Non-Progressive Aphasia: What Can We Learn From Intensive Conversation Groups? [PDF]

Int J Lang Commun Disord
ABSTRACT Background Better Conversations Communication Partner Training (CPT) is delivered to dyads comprising a person with a communication difficulty and a key communication partner (CP). Better Conversations focuses on individualised strategies to promote enjoyable and successful interactions.
Volkmer A, Unger N, Townsend R, Beckley F, Rana M, Feest E, Hollyer A, Dixon L, Watkins K, Beeke S.   +9 more
europepmc   +2 more sources

Non-verbal dichotic listening: A new cognitive hearing test for dementia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Central hearing difficulties are a feature of Alzheimer's disease (AD) but not well captured by standard speech perception tests. METHODS We developed a non‐verbal dichotic listening test (NVDLT) based on everyday sounds, and compared this with a standard verbal dichotic listening test (VDLT) in 36 people with primary progressive ...
Hardy CJD, Levett BA, Jiang J, Core LB, Froud S, Bishop L, Lim D, Durrani F, Volkmer A, Koohi N, Bamiou DE, Marshall CR, Warren JD.   +12 more
europepmc   +2 more sources

Logopenic aphasia due to Lewy body disease dramatically improved with donepezil [PDF]

ENeurologicalSci, 2020
Yoshiyuki Nishio, Toru Baba, Michinori Ezura   +2 more
exaly   +2 more sources

Multidimensional cognitive deficit in logopenic variant primary progressive aphasia: a case report [PDF]

Journal of Medical Case Reports
Introduction Logopenic variant primary progressive aphasia (lvPPA) is a language-led presentation of Alzheimer’s disease that is easily overlooked in older patients with vascular and systemic comorbidities. Case presentation We report a 78-year-old right-
Vivien Puspitasari, Yetty Ramli, Diatri Nari Lastri, Pukovisa Prawiroharjo, Jeremiah Hilkiah Wijaya   +4 more
doaj   +2 more sources