Results 11 to 20 of about 2,380 (167)

Ideomotor apraxia in agrammatic and logopenic variants of primary progressive aphasia [PDF]

Journal of Neurology, 2013
There are few studies examining praxis in subjects with primary progressive aphasia. The aim of this study was to examine the pattern and severity of ideomotor apraxia in subjects with logopenic and agrammatic variants of primary progressive aphasia and to determine if the presence of ideomotor apraxia correlated with specific neuroanatomical ...
Jennifer L Whitwell, Joseph R Duffy, Keith A Josephs   +2 more
exaly   +3 more sources

Progressive logopenic/phonological aphasia: Erosion of the language network

NeuroImage, 2010
The primary progressive aphasias (PPA) are paradigmatic disorders of language network breakdown associated with focal degeneration of the left cerebral hemisphere. Here we addressed brain correlates of PPA in a detailed neuroanatomical analysis of the third canonical syndrome of PPA, logopenic/phonological aphasia (LPA), in relation to the more widely ...
Jonathan D Rohrer, Gérard R Ridgway, Johanna C Goll   +2 more
exaly   +3 more sources

Logopenic aphasia due to Lewy body disease dramatically improved with donepezil [PDF]

ENeurologicalSci, 2020
Toru Baba, Michinori Ezura, Yumiko Saito   +2 more
exaly   +2 more sources

Identifying neuropathologic disease in primary progressive aphasia using narrative speech. [PDF]

Alzheimers Dement
Abstract INTRODUCTION We present an application of artificial intelligence to narrative speech with the primary objective of predicting neuropathologic disease underlying primary progressive aphasia (PPA). METHODS Using natural language processing toolkits, features were extracted from transcribed narratives of the Cinderella story.
Gutstein DB, Iorga M, Stocks J, Gill N, Sleeman J, Gefen TD, Los M, Nelson C, Geula C, Weintraub S, Parrish T, Mesulam MM, Barbieri E.   +12 more
europepmc   +2 more sources

"Doing the Best I Can": Qualitative Outcomes and Participant Feedback From a Combined Communication and Counselling Treatment for Primary Progressive Aphasia. [PDF]

Int J Lang Commun Disord
ABSTRACT Introduction There is a growing evidence base supporting the utility of restitutive speech‐language treatments for individuals with primary progressive aphasia (PPA). In contrast, there is limited research investigating treatment approaches that offer counselling to this population.
Schaffer Mendez K, Evans WS, Dutcher CD, Philburn C, Wauters LD, Young MM, Henry ML.   +6 more
europepmc   +2 more sources

Eligibility for Anti‐Amyloid‐β Monoclonal Antibodies in Patients With Primary Progressive Aphasia due to Alzheimer's Disease in Japan [PDF]

Psychogeriatrics
ABSTRACT Background Primary progressive aphasia (PPA) is a clinical syndrome characterized by progressive language impairment. The logopenic variant (lvPPA) is frequently associated with Alzheimer's disease (AD) pathology. With the approval of anti‐amyloid‐β monoclonal antibodies, such as lecanemab and donanemab, for the treatment of AD, accurately ...
Inagawa S, Inagawa Y, Tsugawa A, Takenoshita N, Saito K, Ishii K, Kasuga K, Ikeuchi T, Shimizu S.   +8 more
europepmc   +2 more sources

A Case of Logopenic Variant of Primary Progressive Aphasia with Parkinsonism and Anosmia

Journal of Alzheimer's Disease Reports, 2020
A 69-year-old right-handed woman developed difficulty naming objects and word-finding. The clinical features of language disorder and predominant atrophy on MRI and predominant hypoperfusion on 123 I-IMP SPECT in the left temporo-parietal junction area ...
Shoichi Sasaki
doaj   +4 more sources

Case Report: A neurolinguistic and neuroimaging study on a Chinese follow-up case with logopenic-variant of primary progressive aphasia

Frontiers in Neurology, 2022
Primary progressive aphasia (PPA), typically resulting from a neurodegenerative disease, is characterized by a progressive loss of specific language functions while other cognitive domains are relatively unaffected.
Binyao Huang, Xiaolu Wang, Biao Jiang, Linlin Kong, Haifeng Hou, Jiong Zhou   +5 more
doaj   +1 more source

FDG PET and MRI in logopenic primary progressive aphasia versus dementia of the Alzheimer's type. [PDF]

PLoS ONE, 2013
The logopenic variant of primary progressive aphasia is an atypical clinical variant of Alzheimer's disease which is typically characterized by left temporoparietal atrophy on magnetic resonance imaging and hypometabolism on F-18 fluorodeoxyglucose ...
Ajay Madhavan, Jennifer L Whitwell, Stephen D Weigand, Joseph R Duffy, Edythe A Strand, Mary M Machulda, Nirubol Tosakulwong, Matthew L Senjem, Jeffrey L Gunter, Val J Lowe, Ronald C Petersen, Clifford R Jack, Keith A Josephs   +12 more
doaj   +1 more source

Aphasic mild cognitive impairment in prodromal dementia with Lewy bodies

Frontiers in Neurology, 2023
IntroductionThis study aimed to determine the characteristics of aphasic mild cognitive impairment (aphasic MCI), which is characterized by a progressive and relatively prominent language impairment compared with other cognitive impairments, in the ...
Hiroyuki Watanabe, Hiroyuki Watanabe, Hiroyuki Watanabe, Sakura Hikida, Sakura Hikida, Manabu Ikeda, Manabu Ikeda, Etsuro Mori, Etsuro Mori   +8 more
doaj   +1 more source