Results 11 to 20 of about 4,326 (212)

Network anatomy in logopenic variant of primary progressive aphasia

Human Brain Mapping, 2023
AbstractThe logopenic variant of primary progressive aphasia (lvPPA) is a neurodegenerative syndrome characterized linguistically by gradual loss of repetition and naming skills, resulting from left posterior temporal and inferior parietal atrophy.
Maria Luisa Mandelli, Diego L. Lorca-Puls, Sladjana Lukic, Maxime Montembeault, Andrea Gajardo-Vidal, Abigail Licata, Aaron Scheffler, Giovanni Battistella, Stephanie M Grasso, Rian Bogley, Buddhika M. Ratnasiri, Renaud La Joie, Nidhi S. Mundada, Eduardo Europa, Gil Rabinovici, Bruce L. Miller, Jessica De Leon, Maya L. Henry, Zachary Miller, Maria Luisa Gorno-Tempini   +19 more
openaire   +7 more sources

Identification of an atypical variant of logopenic progressive aphasia [PDF]

Brain and Language, 2013
The purpose of this study was to examine the association between aphasia severity and neurocognitive function, disease duration and temporoparietal atrophy in 21 individuals with the logopenic variant of primary progressive aphasia (lvPPA). We found significant correlations between aphasia severity and degree of neurocognitive impairment as well as ...
Mary M, Machulda, Jennifer L, Whitwell, Joseph R, Duffy, Edythe A, Strand, Pamela M, Dean, Matthew L, Senjem, Clifford R, Jack, Keith A, Josephs   +7 more
openaire   +4 more sources

Progressive logopenic/phonological aphasia: Erosion of the language network

NeuroImage, 2010
The primary progressive aphasias (PPA) are paradigmatic disorders of language network breakdown associated with focal degeneration of the left cerebral hemisphere. Here we addressed brain correlates of PPA in a detailed neuroanatomical analysis of the third canonical syndrome of PPA, logopenic/phonological aphasia (LPA), in relation to the more widely ...
Rohrer, Jonathan D., Ridgway, Gerard R., Crutch, Sebastian J., Hailstone, Julia, Goll, Johanna C., Clarkson, Matthew J., Mead, Simon, Beck, Jonathan, Mummery, Cath, Ourselin, Sebastien, Warrington, Elizabeth K., Rossor, Martin N., Warren, Jason D.   +12 more
openaire   +4 more sources

Ideomotor apraxia in agrammatic and logopenic variants of primary progressive aphasia [PDF]

Journal of Neurology, 2013
There are few studies examining praxis in subjects with primary progressive aphasia. The aim of this study was to examine the pattern and severity of ideomotor apraxia in subjects with logopenic and agrammatic variants of primary progressive aphasia and to determine if the presence of ideomotor apraxia correlated with specific neuroanatomical ...
Anahita, Adeli, Jennifer L, Whitwell, Joseph R, Duffy, Edyth A, Strand, Keith A, Josephs   +4 more
openaire   +4 more sources

Symptom‐based staging for logopenic variant primary progressive aphasia

European Journal of Neurology
AbstractBackground and purposeLogopenic variant primary progressive aphasia (lvPPA) is a major variant presentation of Alzheimer's disease (AD) that signals the importance of communication dysfunction across AD phenotypes. A clinical staging system is lacking for the evolution of AD‐associated communication difficulties that could guide diagnosis and ...
Chris Hardy, Cathleen Taylor‐Rubin, Beatrice Taylor, Emma Harding, Aida Suárez‐González, Jessica Jiang, Laura M. Thompson, Rachel Kingma, Anthipa Chokesuwattanaskul, Ffion Walker, Steve Barker, Emilie Brotherhood, Claire Waddington, Olivia Wood, Nikki Zimmermann, Nuriye Kupeli, Keir Yong, Paul M. Camic, Joshua Stott, Charles R. Marshall, Neil P. Oxtoby, Jonathan D. Rohrer, Frankie O'Shea, Anna Volkmer, Sebastian J. Crutch, Jason D. Warren   +25 more
openaire   +5 more sources

Logopenic aphasia due to Lewy body disease dramatically improved with donepezil. [PDF]

eNeurologicalSci, 2020
Kakinuma K, Baba T, Ezura M, Endo K, Saito Y, Narita W, Iizuka O, Nishio Y, Kikuchi A, Hasegawa T, Aoki M, Suzuki K.   +11 more
europepmc   +2 more sources

Automated item-level measures of verbal fluency in semantic and logopenic primary progressive aphasia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Verbal fluency tasks are widely used in primary progressive aphasia (PPA), but most studies rely only on total correct responses, overlooking qualitative features of the words produced. We applied a scalable computational framework to extract item‐level features from fluency responses in semantic variant (svPPA) and logopenic ...
Vonk JMJ, Ferrante FJ, Morin BT, Rodriguez DA, Lin M, Bogley R, de Leon J, Tee BL, Santos-Santos MÁ, Miller ZA, Mandelli ML, Gorno-Tempini ML, García AM.   +12 more
europepmc   +2 more sources

A presumptive association between obsessive compulsions and asymmetric temporal lobe atrophy: a case report

Journal of Medical Case Reports, 2022
Background The relatively isolated atrophy of the temporal lobes leads to a clinical radiological pattern, referred to as the temporal variant of frontotemporal dementia.
Thiago Paranhos, Tiago Lucas, Antonio de Salles, Jorge Moll, Ricardo de Oliveira-Souza   +4 more
doaj   +1 more source

Clinical Amyloid Imaging in Logopenic Progressive Aphasia [PDF]

Alzheimer Disease & Associated Disorders, 2015
The introduction of florbetapir (Amyvid) positron emission tomography biomarkers could dramatically change how we clinically evaluate young patients who present with nonamnestic cognitive complaints for possible Alzheimer disease (AD). Logopenic progressive aphasia (LPA) may be the most common example of this type of clinical problem.
Mario F, Mendez, Valeriy, Sabodash
openaire   +2 more sources

The logopenic variant of primary progressive aphasia [PDF]

Current Opinion in Neurology, 2010
The aim is to explore the evolution of the logopenic variant of primary progressive aphasia as a distinct clinical entity and to outline recent advances that have clarified its clinical characteristics, neural underpinnings, and potential genetic and pathological bases.
Henry ML, Gorno Tempini, Maria Luisa
openaire   +2 more sources