Optical Coherent Tomography as a Potential Biomarker for Logopenic Variant Primary Progressive Aphasia: A Cross‐Sectional Prospective Study [PDF]
Abstract Background The logopenic variant of Primary Progressive Aphasia (lvPPA) is a neurodegenerative disorder affecting primarily language functions. In 86% of lvPPA cases, the underlying pathology is amyloidopathy, as seen in Alzheimer's disease (AD).
Wu F +4 more
europepmc +2 more sources
Uma paciente com afasia progressiva primária devido à doença de Alzheimer [PDF]
Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Department of Neurology and NeurosurgeryUNIFESP, EPM, Department of Neurology and ...
Bertolucci, Paulo Henrique Ferreira +2 more
core +2 more sources
Primary progressive aphasia is a neurodegenerative disorder that was recently classified into three types: fluent (semantic), nonfluent, and logopenic.
Stephanie M. Awad, Amer M. Awad
doaj +1 more source
Speech disorders in primary progressive aphasia (PPA)
Introduction : Primary progressive aphasia (PPA) is a group of neurodegenerative disorders whose main feature is speech and language dysfunction. There are three main forms of PPA - non-fluent variant - agrammatic (nfvPPA), semantic variant (svPPA) and ...
Katarzyna Mielniczek +4 more
doaj +1 more source
The Neural Basis of Logopenic Progressive Aphasia
Logopenic progressive aphasia (LPA) is defined clinically by impairments of naming and sentence repetition. The relationship between these impairments and their neural basis has, however, not yet been determined. We aimed to localize cortical thinning associated with naming and repetition deficits using cortical thickness measurements.
Leyton, Cristian E +5 more
openaire +3 more sources
Comparing Individuals With PPA to Individuals With AD: Cognitive and Linguistic Profiles
Primary Progressive Aphasia (PPA) is a degenerative condition characterized by the progressive loss of language function. In PPA, aphasia is the most prominent deficit at onset.
Nomiki Karpathiou +2 more
doaj +1 more source
Pronounced impairment of activities of daily living in posterior cortical atrophy [PDF]
Introduction : The impact of several dementia syndromes on activities of daily living (ADLs) has been well documented, but no study has yet investigated functional ability in posterior cortical atrophy (PCA).
Ahmed, Samrah +5 more
core +1 more source
Structural, Microstructural, and Metabolic Alterations in Primary Progressive Aphasia Variants
Neuroimaging studies have described the brain alterations in primary progressive aphasia (PPA) variants (semantic, logopenic, nonfluent/agrammatic). However, few studies combined T1, FDG-PET, and diffusion MRI techniques to study atrophy, hypometabolism,
Alexandre Routier +42 more
doaj +1 more source
Primary progressive aphasia: a tale of two syndromes and the rest [PDF]
Objective: Primary progressive aphasia (PPA) has been proposed to comprise 3 discrete clinical subtypes: semantic, agrammatic/nonfluent, and logopenic.
Arnold, R. J. +4 more
core +1 more source
Diagnosing Dementia in the Clinical Setting: Can Amyloid PET Provide Additional Value Over Cerebrospinal Fluid? [PDF]
Cerebrospinal fluid (CSF) measures of amyloid and tau are the first-line Alzheimer's disease biomarkers in many clinical centers. We assessed if and when the addition of amyloid PET following CSF measurements provides added diagnostic value.
Barnes, A +12 more
core +1 more source

