Results 41 to 50 of about 4,326 (212)

Microbleeds in the logopenic variant of primary progressive aphasia [PDF]

Alzheimer's & Dementia, 2013
AbstractBackgroundMicrobleeds have been associated with Alzheimer's disease (AD), although it is unclear whether they occur in atypical presentations of AD, such as the logopenic variant of primary progressive aphasia (lvPPA). We aimed to assess the presence and clinical correlates of microbleeds in lvPPA.MethodsThirteen lvPPA subjects underwent 3T T2*‐
Jennifer L, Whitwell, Clifford R, Jack, Joseph R, Duffy, Edythe A, Strand, Jeffrey L, Gunter, Matthew L, Senjem, Matthew C, Murphy, Kejal, Kantarci, Mary M, Machulda, Val J, Lowe, Keith A, Josephs   +10 more
openaire   +2 more sources

Qualitative Assessment of Verbal Fluency Performance in Frontotemporal Dementia [PDF]

, 2017
Background/Aims: Verbal fluency is impaired in patients with frontotemporal dementia (FTD) and primary progressive aphasia (PPA). This study explored qualitative differences in verbal fluency (clustering of words, switching between strategies) between ...
Berg, E. (Esther) van den, Grosveld, M.J.H. (Mariëlle J.H.), Jiskoot, L.C. (Lize), Papma, J.M. (Janne), Swieten, J.C. (John) van   +4 more
core   +1 more source

Difficulties of clinical diagnosis in primary progressive aphasia. Clinical observation

Анналы клинической и экспериментальной неврологии, 2019
Primary progressive aphasia is a syndrome characterized by progressive speech dysfunction. There are three types of this condition. The first agrammatic type of primary progressive aphasia is typical for frontotemporal dementia and characterized by ...
Yevgeniy P. Barantsevich, Yuri P. Koval’chuk, Yekaterina V. Mel’nik, Vladimir S. Emanuel’, Yulia V. Emanuel’   +4 more
doaj   +1 more source

The clinical spectrum of sporadic and familial forms of frontotemporal dementia [PDF]

, 2016
The term frontotemporal dementia (FTD) describes a clinically, genetically and pathologically diverse group of neurodegenerative disorders. Symptoms of FTD can present in individuals in their twenties through to their nineties, but the mean age at onset ...
Rohrer, JD, Woollacott, IO
core   +1 more source

Neuroanatomical correlates of phonologic errors in logopenic progressive aphasia

Brain and Language, 2020
While phonologic errors may be one of the salient features of the logopenic variant of primary progressive aphasia (lvPPA), sparse data are available on their neuroimaging correlates. The purpose of this study was to identify brain regions associated with different types of phonologic errors across several tasks for participants with lvPPA ...
Diana, Petroi, Joseph R, Duffy, Andrew, Borgert, Edythe A, Strand, Mary M, Machulda, Matthew L, Senjem, Clifford R, Jack, Keith A, Josephs, Jennifer L, Whitwell   +8 more
openaire   +3 more sources

Logopenic aphasia or Alzheimer's disease: Different phases of the same disease?

Dementia & Neuropsychologia
The logopenic variant of Primary Progressive Aphasia, or logopenic aphasia, is a the most recently described variant of Primary Progressive Aphasia and also the least well defined.
Bárbara Costa Beber, Renata Kochhann, Bruna Matias da Silva, Marcia L. F. Chaves   +3 more
doaj   +1 more source

Change of Accent as an Atypical Onset of non Fluent Primary Progressive Aphasia

Behavioural Neurology, 2013
Language disorders can be the first symptom of many neurodegenerative diseases, including Alzheimer's disease (AD) and primary progressive aphasia (PPA).
Susy Paolini, Lucia Paciaroni, Antonio Manca, Roberto Rossi, Daniela Fornarelli, Stefano F. Cappa, Angela M. Abbatecola, Osvaldo Scarpino   +7 more
doaj   +1 more source

Retained capacity for perceptual learning of degraded speech in primary progressive aphasia and Alzheimer’s disease

Alzheimer’s Research & Therapy, 2018
Background Processing of degraded speech is a promising model for understanding communication under challenging listening conditions, core auditory deficits and residual capacity for perceptual learning and cerebral plasticity in major dementias. Methods
Chris J. D. Hardy, Charles R. Marshall, Rebecca L. Bond, Lucy L. Russell, Katrina Dick, Cono Ariti, David L. Thomas, Sonya J. Ross, Jennifer L. Agustus, Sebastian J. Crutch, Jonathan D. Rohrer, Doris-Eva Bamiou, Jason D. Warren   +12 more
doaj   +1 more source

Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia

Brain Sciences, 2021
“Functional communication” refers to an individual’s ability to communicate effectively in his or her everyday environment, and thus is a paramount skill to monitor and target therapeutically in people with aphasia.
Jeanne Gallée, Claire Cordella, Evelina Fedorenko, Daisy Hochberg, Alexandra Touroutoglou, Megan Quimby, Bradford C. Dickerson   +6 more
doaj   +1 more source

Eligibility for Anti‐Amyloid‐β Monoclonal Antibodies in Patients With Primary Progressive Aphasia due to Alzheimer's Disease in Japan [PDF]

Psychogeriatrics
ABSTRACT Background Primary progressive aphasia (PPA) is a clinical syndrome characterized by progressive language impairment. The logopenic variant (lvPPA) is frequently associated with Alzheimer's disease (AD) pathology. With the approval of anti‐amyloid‐β monoclonal antibodies, such as lecanemab and donanemab, for the treatment of AD, accurately ...
Inagawa S, Inagawa Y, Tsugawa A, Takenoshita N, Saito K, Ishii K, Kasuga K, Ikeuchi T, Shimizu S.   +8 more
europepmc   +2 more sources