Results 61 to 70 of about 34,580 (193)

‘It Is of Course About Being Human Together’: Co‐Development of a Primary Progressive Aphasia Awareness Campaign to Enhance Understanding of Speech and Language Therapy

International Journal of Language &Communication Disorders, Volume 61, Issue 5, September/October 2026.
ABSTRACT Introduction Globally, there is a lack of awareness of rare dementias such as those led by language decline (the primary progressive aphasias, PPA). The main treatment for PPA is speech and language therapy, yet many people are unaware of the benefits and are often not referred on by other health care professionals.
Anna Volkmer, Rosemary Townsend, Bethany Anthony, Sharon M. Antonucci, Petronilla Battista, Sandrine Basaglia‐Pappas, Jeanne Gallée, Stephanie Grasso, Maya L. Henry, Peter Just, Nomiki Karpathiou, Becky Khayum, Monica Lavoie, Helen Moffat, Michael Petley, Philip Robinson, Kiiya Shibata, Cathleen Taylor‐Rubin, Vanessa Ward, Jason D. Warren, Nikki Zimmerman, the BCPPA Patient and Public Involvement Group   +21 more
wiley   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove, Sara Van Mossevelde, Marijke Miatton, Jan De Lepeleire, Rose Bruffaerts, Jean Christophe Bier, Kurt Segers, Jurn Verschraegen, Mirko Petrovic, Manfredi Ventura, Haroun Jedidi, Ingo Beyer, Eric Mormont, Rik Vandenberghe, Aline Delva, Christian Gilles, Donatienne Van Weehaeghe, Gaëtane Picard, Peter De Deyn, Mélanie Strauss, Evert Thiery, Eric Salmon, Gert Cypers, Joris Vlaemynck, Katrin Gillis, Jan Versijpt, Maria Bjerke, Anne Sieben, Bernard Hanseeuw, Sebastiaan Engelborghs, Olivier Deryck, on behalf of the BeDeCo members   +31 more
wiley   +1 more source

A decade with anomic primary progressive aphasia

eNeurologicalSci
Some patients with primary progressive aphasia (PPA) demonstrate only anomia. The lack of longitudinal observations of anomic PPA precluded us from determining whether progressive anomic aphasia was simply an early stage of semantic or logopenic variants,
Shoko Ota, Kazuo Kakinuma, Wataru Narita, Yoshiyuki Nishio, Nobuko Kawakami, Ayane Tamagake, Shigenori Kanno, Minoru Matsuda, Kyoko Suzuki   +8 more
doaj   +1 more source

Progranulin-associated PiB-negative logopenic primary progressive aphasia [PDF]

Journal of Neurology, 2014
The logopenic variant of primary progressive aphasia (lvPPA) strongly associates with Alzheimer's disease, but can also associate with frontotemporal lobar degeneration. We aimed to assess the frequency of lvPPA in patients with speech and language disorders without β-amyloid deposition, and to perform detailed neuroimaging and genetic testing in such ...
Keith A, Josephs, Joseph R, Duffy, Edythe A, Strand, Mary M, Machulda, Prashanthi, Vemuri, Matthew L, Senjem, Ralph B, Perkerson, Matthew C, Baker, Val, Lowe, Clifford R, Jack, Rosa, Rademakers, Jennifer L, Whitwell   +11 more
openaire   +2 more sources

Deciphering logopenic primary progressive aphasia: a clinical, imaging and biomarker investigation.

, 2013
International audienceWithin primary progressive aphasia the logopenic variant remains less understood than the two other main variants, namely semantic and non-fluent progressive aphasia.
Migliaccio, Raffaella, Rogan, Christina, Samri, Dalila, Ferrieux, Sophie, Boutet, Claire, Dubois, Bruno, Kas, Aurélie, Teichmann, Marc, Dormont, Didier, Nogues, Marie   +9 more
core   +1 more source

Classification of primary progressive aphasia: challenges and complexities [version 1; peer review: 2 approved]

F1000Research, 2020
Primary progressive aphasia (PPA) is classified into three variants, logopenic variant PPA (lvPPA), nonfluent agrammatic PPA (nfaPPA), and semantic variant PPA (svPPA), based on clinical (syndromic) characteristics with support from neuroimaging and/or ...
Donna C. Tippett
doaj   +1 more source

Cognitive and Neural Mechanisms of Social Communication Dysfunction in Primary Progressive Aphasia

Brain Sciences, 2021
Mounting evidence suggests that, in parallel with well-defined changes in language, primary progressive aphasia (PPA) syndromes display co-occurring social cognitive impairments.
Zoë-Lee Goldberg, Hashim El-Omar, David Foxe, Cristian E. Leyton, Rebekah M. Ahmed, Olivier Piguet, Muireann Irish   +6 more
doaj   +1 more source

Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neurodegenerative pathologies

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION The impact of different neuropathologies on deep brain structures remains to be understood. We examine subcortical and limbic volumetry in neurodegenerative diseases involving phosphorylated tau (p‐tau), α‐synuclein, and transactive response DNA binding protein 43 (TDP‐43).
Pulkit Khandelwal, Michael Tran Duong, Lisa M. Levorse, Winifred Trotman, Alejandra Bahena, Sydney A. Lim, Amanda E. Denning, Eunice Chung, Christopher A. Olm, Hamsanandini Radhakrishnan, Ranjit Ittyerah, Karthik Prabhakaran, Gabor Mizsei, Theresa Schuck, Sheina Emrani, Joaquin A. Vizcarra, John Robinson, Daniel T. Ohm, Jeffrey S. Phillips, Jesse Cohen, Laura E. M. Wisse, John A. Detre, Ilya M. Nasrallah, Christopher A. Brown, Sandhitsu R. Das, Edward B. Lee, M. Dylan Tisdall, David J. Irwin, Corey T. McMillan, David A. Wolk, Paul A. Yushkevich   +30 more
wiley   +1 more source

A Middle-Aged Woman with Logopenic Progressive Aphasia as a Precursor of Alzheimer's Disease: Case Report and Review of the Literature [PDF]

, 2020
Primary progressive aphasia is a neurodegenerative disorder that was recently classified into three types: fluent (semantic), nonfluent, and logopenic.
Stephanie M Awad, Amer M Awad
core  

Clinical Correlates of Alzheimer's Disease Cerebrospinal Fluid Analytes in Primary Progressive Aphasia

Frontiers in Neurology, 2019
Background: While primary progressive aphasia (PPA) is associated with frontotemporal lobar degeneration (FTLD) pathology due to tau or TDP, clinical-pathological studies also demonstrate many cases have Alzheimer's disease (AD) pathology.
Catherine Norise, Molly Ungrady, Amy Halpin, Charles Jester, Corey T. McMillan, David J. Irwin, Katheryn A. Cousins, Murray Grossman   +7 more
doaj   +1 more source