Results 61 to 70 of about 4,326 (212)

Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case–Control Study and Call for a Consensus

Annals of Neurology, Volume 99, Issue 4, Page 1046-1058, April 2026.
[Color figure can be viewed at www.annalsofneurology.org] Objective Sleep‐predominant network hyperexcitability is increasingly recognized as a potential disease‐accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk‐factors remain debated, largely due to cohort‐specific and methodological differences across studies.
Anna B. Szabo, Jonathan Curot, Fleur Gérard, Florence Rulquin, Rachel Debs, Claire Georges, Marie Denuelle, Amel Bouloufa, Béatrice Lemesle, Patrice Péran, Claire Thalamas, Emmanuel J. Barbeau, Jérémie Pariente, Lionel Dahan, Luc Valton   +14 more
wiley   +1 more source

Neologistic jargon aphasia and agraphia in primary progressive aphasia [PDF]

, 2009
The terms 'jargon aphasia' and 'jargon agraphia' describe the production of incomprehensible language containing frequent phonological, semantic or neologistic errors in speech and writing, respectively.
Rohrer, JD, Rossor, MN, Warren, JD
core  

Behavioral, computational, and neuroimaging studies of acquired apraxia of speech [PDF]

, 2014
A critical examination of speech motor control depends on an in-depth understanding of network connectivity associated with Brodmann areas 44 and 45 and surrounding cortices.
Ballard, Kirrie J., Robin, Donald A., Tourville, Jason A.   +2 more
core   +1 more source

Tau PET overlap index correlation with neuropathological findings

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The tau positron emission tomography (PET) overlap index (OI) has shown promise in maximizing signal‐to‐noise for longitudinal tau PET imaging, particularly for early tau pathology, but requires validation against neuropathology.
Seokbeen Lim, Jeyeon Lee, Paul H. Min, Christina M. Moloney, Carly T. Mester, Sujala Ghatamaneni, Matthew L. Senjem, Hugo Botha, David S. Knopman, Stuart J. McCarter, Vijay K. Ramanan, Rodolfo Savica, Julie A. Fields, Mary M. Machulda, Dennis W. Dickson, R. Ross Reichard, Aivi T. Nguyen, Jonathan Graff‐Radford, Christopher G. Schwarz, Jeffrey L. Gunter, Kejal Kantarci, Bradley Boeve, Prashanthi Vemuri, David T. Jones, Clifford R. Jack Jr., Ronald C. Petersen, Melissa E. Murray, Val J. Lowe   +27 more
wiley   +1 more source

A decade with anomic primary progressive aphasia

eNeurologicalSci
Some patients with primary progressive aphasia (PPA) demonstrate only anomia. The lack of longitudinal observations of anomic PPA precluded us from determining whether progressive anomic aphasia was simply an early stage of semantic or logopenic variants,
Shoko Ota, Kazuo Kakinuma, Wataru Narita, Yoshiyuki Nishio, Nobuko Kawakami, Ayane Tamagake, Shigenori Kanno, Minoru Matsuda, Kyoko Suzuki   +8 more
doaj   +1 more source

Cognitive and Neural Mechanisms of Social Communication Dysfunction in Primary Progressive Aphasia

Brain Sciences, 2021
Mounting evidence suggests that, in parallel with well-defined changes in language, primary progressive aphasia (PPA) syndromes display co-occurring social cognitive impairments.
Zoë-Lee Goldberg, Hashim El-Omar, David Foxe, Cristian E. Leyton, Rebekah M. Ahmed, Olivier Piguet, Muireann Irish   +6 more
doaj   +1 more source

Classification of primary progressive aphasia: challenges and complexities [version 1; peer review: 2 approved]

F1000Research, 2020
Primary progressive aphasia (PPA) is classified into three variants, logopenic variant PPA (lvPPA), nonfluent agrammatic PPA (nfaPPA), and semantic variant PPA (svPPA), based on clinical (syndromic) characteristics with support from neuroimaging and/or ...
Donna C. Tippett
doaj   +1 more source

Speech‐in‐noise processing in Alzheimer's disease and primary progressive aphasia [PDF]

Alzheimers Dement
Abstract Background In daily life, understanding spoken messages generally requires decoding of speech signals embedded in variably noisy acoustic backgrounds. This is a computationally demanding neural task that is likely to be vulnerable early in the course of neurodegenerative brain pathologies. However, how speech‐in‐noise processing is affected in
Froud S, Levett B, Core L, Jiang J, Marshall C, Warren J, Hardy C.   +6 more
europepmc   +2 more sources

Biparietal variant of Alzheimer's disease: a rare presentation of a common disease [PDF]

, 2015
Alzheimer's disease (AD) is a clinically heterogeneous disease that may have atypical presentations with focal cortical syndromes and relatively preserved episodic memory.
Marques, IB, Milheiro, M, Santana, I, Tábuas-Pereira, M   +3 more
core   +1 more source

Evidence for a pervasive autobiographical memory impairment in Logopenic Progressive Aphasia

Neurobiology of Aging, 2021
Although characterized primarily as a language disorder, mounting evidence indicates episodic amnesia in Logopenic Progressive Aphasia (LPA). Whether such memory disturbances extend to information encoded pre-disease onset remains unclear. To address this question, we examined autobiographical memory in 10 LPA patients, contrasted with 18 typical ...
Siddharth Ramanan, David Foxe, Hashim El-Omar, Rebekah M. Ahmed, John R. Hodges, Olivier Piguet, Muireann Irish   +6 more
openaire   +2 more sources