Results 81 to 90 of about 2,380 (167)

Logopenic aphasia in Alzheimer's disease: clinical variant or clinical feature?

Journal of Neurology, Neurosurgery & Psychiatry, 2012
Primary progressive aphasia (PPA) is a clinical syndrome characterised by progressive decline in components of the language system. Recent evidence suggests that the logopenic/phonological (LPA) variant is a reliable in vivo marker of Alzheimer related pathology.
Ahmed, S, de Jager, C, Haigh, A, Garrard, P   +3 more
openaire   +3 more sources

Present, past and future of Primary Progressive Aphasia: A bibliographic update

Revista de Psicología, 2020
The present study revises the literature regarding the current knowledge about Primary Progressive Aphasia (PPA). The study presents the main diagnostic criteria for PPA and those used to classify patients according to international criteria in one of ...
Federico G. Soriano, Macarena Martínez-Cuitiño   +1 more
doaj  

Memory and Orientation in the Logopenic and Nonfluent Subtypes of Primary Progressive Aphasia

Journal of Alzheimer's Disease, 2014
Memory and orientation were investigated as predictors of underlying Alzheimer's disease (AD) pathology in patients with logopenic (lv) and non-fluent (na) variants of primary progressive aphasia (PPA). Memory and orientation scores from Addenbrooke's Cognitive Examination were compared between 26 lv-PPA, 29 na-PPA, 59 AD, and 90 controls using ...
Flanagan, Emma C., Tu, Sicong, Ahmed, Samrah, Hodges, John R., Hornberger, Michael   +4 more
openaire   +4 more sources

Verbal and Visuospatial Span in Logopenic Progressive Aphasia and Alzheimer's Disease

Journal of the International Neuropsychological Society, 2013
AbstractLogopenic progressive aphasia (LPA) is a form of primary progressive aphasia (PPA) characterized by hesitant speech with marked impairment in naming and repetition. LPA is associated with brain atrophy in the left temporal and inferior parietal cortices and is predominantly associated with Alzheimer's disease (AD) pathology. In contrast to LPA,
Foxe, DG, Irish, M, Hodges, JR, Piguet, Olivier   +3 more
openaire   +3 more sources

Early alteration of the locus coeruleus in phenotypic variants of Alzheimer’s disease

Annals of Clinical and Translational Neurology, 2019
Neuropathological studies showed early locus coeruleus (LC) neuronal loss associated with tauopathy in Alzheimer’s Disease (AD). We used the LC signal intensity (LC‐I) on 3T MRI to assess the LC integrity in AD (n = 37) and controls (n = 17).
Pauline Olivieri, Julien Lagarde, Stéphane Lehericy, Romain Valabrègue, Adeline Michel, Pierre Macé, Fabien Caillé, Philippe Gervais, Michel Bottlaender, Marie Sarazin   +9 more
doaj   +1 more source

Spelling Intervention in Post-Stroke Aphasia and Primary Progressive Aphasia

Behavioural Neurology, 2013
Spelling–a core language skill–is commonly affected in neurological diseases such as stroke and Primary Progressive Aphasia (PPA). We present two case studies of the same spelling therapy (learning of phoneme-to-grapheme correspondences with help from ...
Kyrana Tsapkini, Argye E. Hillis
doaj   +1 more source

Efficacy of Acetylcholinesterase Inhibitors in the Logopenic Variant of Primary Progressive Aphasia

Dementia and Geriatric Cognitive Disorders
Introduction: For over 25 years, cholinesterase inhibitors (ChEIs) have been the main symptomatic treatment for Alzheimer’s disease (AD). Several meta-analyses have supported their effectiveness in various neurocognitive, functional, and behavioral aspects of amnestic AD. Over 86% of cases of the logopenic variant of primary progressive aphasia (lvPPA),
Julie Carrier-Auclair, Monica Lavoie, Maud Tastevin, Robert Laforce Jr.   +3 more
openaire   +2 more sources

Frontotemporal dementia and primary progressive aphasia, a review

Neuropsychiatric Disease and Treatment, 2014
Howard S KirshnerDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USAAbstract: Frontotemporal dementias are neurodegenerative diseases in which symptoms of frontal and/or temporal lobe disease are the first signs of the ...
Kirshner HS
doaj  

Impaired semantic control in the logopenic variant of primary progressive aphasia

Brain Communications
Abstract We investigated semantic cognition in the logopenic variant of primary progressive aphasia (lvPPA), including (i) the status of verbal and non-verbal semantic performance; and (ii) whether the semantic deficit reflects impaired semantic control. Our a priori hypothesis that
Shalom K Henderson, Siddharth Ramanan, Matthew A Rouse, Thomas E Cope, Ajay D Halai, Karalyn E Patterson, James B Rowe, Matthew A Lambon Ralph   +7 more
openaire   +3 more sources

Effects of Cerebellar Transcranial Direct Current Stimulation in Bilingual Logopenic Primary Progressive Aphasia

Journal of Alzheimer's Disease Reports
Background: Primary progressive aphasia (PPA) is a language-based dementia, causing progressive decline of language functions. Transcranial direct current stimulation (tDCS) can augment effects of speech-and language therapy (SLT).
Silke Coemans, Vânia De Aguiar, Philippe Paquier, Kyrana Tsapkini, Sebastiaan Engelborghs, Esli Struys, Stefanie Keulen   +6 more
doaj   +1 more source