Results 81 to 90 of about 4,326 (212)

Coexisting Logopenic Variant of Primary Progressive Aphasia with Amyloid Pathology and Early Parkinsonism

Journal of Alzheimer's Disease Reports
The presence of parkinsonism features in primary progressive aphasia (PPA) is a subject of ongoing research. These features are usually more pronounced in the advanced stages of the disease, particularly in the non-fluent/agrammatic subtype, and are ...
Martina Caccamo, Daniele Urso, Alfredo Gabriele Nanni, Valentina Gnoni, Alessia Giugno, Alessandra Vitulli, Davide Vilella, Chiara Zecca, Maria Teresa Dell’Abate, Antonio Anastasia, Roberto De Blasi, Alessandro Introna, Giancarlo Logroscino   +12 more
doaj   +1 more source

Moving Toward Non-transcription Based Discourse Analysis in Stable and Progressive Aphasia [PDF]

, 2019
Measurement of communication ability at the discourse level holds promise for predicting how well persons with stable (e.g., stroke-induced), or progressive aphasia navigate everyday communicative interactions.
Dalton, Sarah Grace, Hubbard, H. Isabel, Richardson, Jessica D.   +2 more
core   +1 more source

Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic. [PDF]

, 2018
BACKGROUND: Cerebrospinal fluid (CSF) biomarkers are increasingly being used to support a diagnosis of Alzheimer's disease (AD). Their clinical utility for differentiating AD from non-AD neurodegenerative dementias, such as dementia with Lewy bodies (DLB)
Blennow, Kaj, Chapman, Miles D, Foiani, Martha S, Fox, Nick C, Heslegrave, Amanda J, Keshavan, Ashvini, Lunn, Michael P, Magdalinou, Nadia K, Mummery, Catherine J, Nicholas, Jennifer M, Paterson, Ross W, Poole, Teresa, Rohrer, Jonathan D, Rossor, Martin N, Schott, Jonathan M, Slattery, Catherine F, Toombs, Jamie, Warren, Jason D, Weston, Philip SJ, Zetterberg, Henrik   +19 more
core   +1 more source

Development of language composites for enhanced sensitivity to multiple plasma biomarkers

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract BACKGROUND While language deficits are among the earliest detectable signs of Alzheimer`s disease (AD), no existing composites integrate connected speech – essential for capturing real‐world communication – limiting precise detection and personalized interventions.
Deling He, Rebecca E Langhough, Carol Van Hulle, Kristin Basche, Erin Jonaitis, Rachael Wilson, Bruce Hermann, Henrik Zetterberg, Sterling Johnson, Kimberly D. Mueller   +9 more
wiley   +1 more source

Phonological processing in primary progressive aphasia [PDF]

, 2013
Primary progressive aphasia (PPA) is a debilitating condition wherein speech and language deteriorate as a result of neurodegenerative disease. Three variants of PPA are now recognized, each of which shows a unique constellation of speech-language ...
Babiak, Miranda, Beeson, Pelagie M, Gorno-Tempini, Maria Luisa, Henry, Maya L, Z Rapcsak, Steven   +4 more
core  

The Relationship between Behavioural Changes, Cognitive Symptoms, and Functional Disability in Primary Progressive Aphasia: A Longitudinal Study [PDF]

, 2016
Background: The contribution of behavioural changes to functional decline is yet to be explored in primary progressive aphasia (PPA). Objectives: (1) investigate functional changes in two PPA variants [semantic (svPPA) and non-fluent (nfvPPA)], at ...
Brodaty, H., Clemson, L., Flanagan, E., Hodges, J.R., Kaizik, C., Mioshi, E., O'Connor, C.M., Piguet, O.   +7 more
core   +1 more source

Logopenic variant of primary progressive aphasia – Case report

Polish Annals of Medicine, 2016
Abstract Introduction Speech disorders are often first symptoms of dementias with neurodegenerative basis. Differences in the clinical picture and different types of the speech difficulties may make diagnosis of this degenerative process easier. Aim To present an example of clinical evaluation of the patient with primary progressive aphasia (PPA)
Agnieszka Rakowska, Tomasz Matyskieła, Dorota Mroczkowska, Beata Zwiernik, Jacek Zwiernik   +4 more
openaire   +1 more source

The role of bilingualism on functional decline and neurodegeneration in distinct ADRD clinical syndromes

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION We evaluated a large cohort (N = 408) of monolingual and bilingual speakers with Alzheimer's disease and related dementias (ADRD) syndromes and longitudinal markers of functional decline and neurodegeneration to determine whether bilingual speakers show more cognitive resilience to neurodegenerative processes. METHODS Participants
Jonathan Tablante, Kaitlin Casaletto, Lawren VandeVrede, Eugenie Mamuyac, Luna Gao, Jeanine Sandra Esteban, Ariel Guevarra, Jaeda Johnson, Mia Rios, Luis Martinez, Niecholle Roco, Isabel Elaine Allen, Stephanie M. Grasso, Maria Luisa Gorno‐Tempini, Lea T. Grinberg, Nina Dronkers, Emily W. Paolillo, Jessica de Leon   +17 more
wiley   +1 more source

Essential Considerations for Diagnosing Primary Progressive Aphasia

Journal of Indian Speech Language & Hearing Association
Language impairments vary widely and are often linked to brain dysfunction. While classic aphasia usually occurs after brain injury, other conditions, such as primary progressive aphasia (PPA), occur due to neurodegeneration of the brain.
P. B. Jaya Lakshmi, S. Anusha Rao, G. Shirley Kerense Arockiamary, B. Nandhini   +3 more
doaj   +1 more source

Learning and adaptation in speech production without a vocal tract [PDF]

, 2019
How is the complex audiomotor skill of speaking learned? To what extent does it depend on the specific characteristics of the vocal tract? Here, we developed a touchscreen-based speech synthesizer to examine learning of speech production independent of ...
Houde, John F., Nagarajan, Srikantan S., Thompson, Megan M. C.   +2 more
core   +1 more source