Results 51 to 60 of about 4,326 (212)

Neuroimaging biomarkers of neurodegenerative diseases and dementia [PDF]

, 2013
Neurodegenerative disorders leading to dementia are common diseases that affect many older and some young adults. Neuroimaging methods are important tools for assessing and monitoring pathological brain changes associated with progressive ...
Risacher, Shannon L., Saykin, Andrew J.
core   +1 more source

Dual-phase 18F-florbetapir positron emission tomography in patients with primary progressive aphasia, Alzheimer's disease, and healthy controls: A preliminary study

Journal of the Formosan Medical Association, 2017
Background/Purpose: To determine whether dual-phase 18F-florbetapir positron emission tomography imaging with perfusion-like and amyloid deposition information can distinguish among primary progressive aphasia (PPA), Alzheimer's disease (AD), and healthy
Hung-Chou Kuo, Ing-Tsung Hsiao, Chia-Ju Hsieh, Chu-Yun Huang, Kuo-Lun Huang, Yau-Yau Wai, Wen-Li Chuang, Mei-Ping Kung, Yi-Chuan Chu, Tzu-Chen Yen, Kun-Ju Lin, Chin-Chang Huang   +11 more
doaj   +1 more source

Olfactory and imaging features in atypical Alzheimer’s disease

Translational Neuroscience, 2018
Cognition and speech disorders are the most common symptoms of dementia in neurodegenerative disease. Here, we present a detailed clinical evaluation of a case of logopenic variant of primary progressive aphasia (lv-PPA), an atypical form of Alzheimer ...
Huihong Zhang, Pan Wang, Chunfeng Zhang, Yan Wang, Hui Zhang, Li Cai, Yuying Zhou   +6 more
doaj   +1 more source

Thematic Integration Impairments in Primary Progressive Aphasia: Evidence From Eye-Tracking

Frontiers in Human Neuroscience, 2021
Primary progressive aphasia (PPA) is a degenerative disease affecting language while leaving other cognitive facilities relatively unscathed. The agrammatic subtype of PPA (PPA-G) is characterized by agrammatic language production with impaired ...
Matthew Walenski, Jennifer E. Mack, M. Marsel Mesulam, Cynthia K. Thompson, Cynthia K. Thompson, Cynthia K. Thompson   +5 more
doaj   +1 more source

Distinct regional patterns of synaptic vulnerability across hippocampal and parahippocampal subregions in Alzheimer's disease

Brain Pathology, EarlyView.
Synaptic loss in Alzheimer's disease predominantly affects the entorhinal cortex and parahippocampal gyrus. Amyloid‐β and p‐tau pathology show global associations with synaptic density but are limited in specific subregions. Instead, axonal damage associates with synaptic loss locally and in interconnected subregions.
Maud M. A. Bouwman, Irene Frigerio, Yvon Galis‐de Graaf, Wilma D. J. van de Berg, Laura E. Jonkman   +4 more
wiley   +1 more source

Posterior cortical atrophy in logopenic progressive aphasia: A case report

Frontiers in Communication, 2022
Posterior Cortical Atrophy (PCA) and Logopenic progressive aphasia (LPA) are nonamnestic variants of Alzheimer's disease (AD). Language deficits are a hallmark of LPA but not PCA.
Darshini Jeevendra Kumar, Sheetal Goyal, Faheem Arshad, Vandana Valiyaparambath Purushothaman, Subasree Ramakrishnan, Suvarna Alladi   +5 more
doaj   +1 more source

Criteria for the diagnosis of corticobasal degeneration [PDF]

, 2013
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations.
Armstrong, Melissa J, Bak, Thomas H, Bhatia, Kailash P, Borroni, Barbara, Boxer, Adam L, Dickson, Dennis W, Grossman, Murray, Hallett, Mark, Josephs, Keith A, Kertesz, Andrew, Lang, Anthony E, Lee, Suzee E, Litvan, Irene, Miller, Bruce L, Reich, Stephen G, Riley, David E, Tolosa, Eduardo, Tröster, Alexander I, Vidailhet, Marie, Weiner, William J   +19 more
core   +1 more source

Addressing Future Changes in Communication Using Hypothetical Scenarios With People With Primary Progressive Aphasia and Care Partners: A Conversation Analytic Study

International Journal of Language &Communication Disorders, Volume 61, Issue 3, May/June 2026.
ABSTRACT Background People with primary progressive aphasia (PPA) will experience a decline in language and cognitive function, and behavioural changes are not uncommon. Decline in everyday skills has been reported and becomes more pronounced over time.
Winsnes Ingvild, Halvorsen Mia, Krogh Elise, Volkmer Anna   +3 more
wiley   +1 more source

Lack of Frank Agrammatism in the Nonfluent Agrammatic Variant of Primary Progressive Aphasia

Dementia and Geriatric Cognitive Disorders Extra, 2016
Background/Aims: Frank agrammatism, defined as the omission and/or substitution of grammatical morphemes with associated grammatical errors, is variably reported in patients with nonfluent variant primary progressive aphasia (nfPPA). This study addressed
Naida L. Graham, Carol Leonard, David F. Tang-Wai, Sandra Black, Tiffany W. Chow, Chris J.M. Scott, Alicia A. McNeely, Mario Masellis, Elizabeth Rochon   +8 more
doaj   +1 more source

Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from cortical dementias

, 2010
International audienceBackground: Considering that most of semantic dementia (SD) and frontotemporal dementia (FTD) patients show no postmortem Alzheimer's disease (AD) pathology, cerebrospinal fluid (CSF) biomarkers may be of value for distinguishing ...
Belliard, Serge, Cruz De Souza, Leonardo, De Paz, Raphael, Dubois, Bruno, Houillier, Caroline, Jardel, Claude, Lamari, Foudil, Sarazin, Marie   +7 more
core   +4 more sources