Results 21 to 30 of about 4,326 (212)

Identifying neuropathologic disease in primary progressive aphasia using narrative speech. [PDF]

Alzheimers Dement
Abstract INTRODUCTION We present an application of artificial intelligence to narrative speech with the primary objective of predicting neuropathologic disease underlying primary progressive aphasia (PPA). METHODS Using natural language processing toolkits, features were extracted from transcribed narratives of the Cinderella story.
Gutstein DB, Iorga M, Stocks J, Gill N, Sleeman J, Gefen TD, Los M, Nelson C, Geula C, Weintraub S, Parrish T, Mesulam MM, Barbieri E.   +12 more
europepmc   +2 more sources

The Landscape Montage Technique for diagnosing frontotemporal dementia starting as primary progressive aphasia: a case report

Journal of Medical Case Reports, 2020
Background The Landscape Montage Technique was originally developed by Hisao Nakai, a Japanese psychiatrist, to pursue the possibility and application of a psychotherapeutic approach using drawing for patients with schizophrenia.
Masahiko Takaya, Kazunari Ishii, Isao Kubota, Osamu Shirakawa   +3 more
doaj   +1 more source

"Doing the Best I Can": Qualitative Outcomes and Participant Feedback From a Combined Communication and Counselling Treatment for Primary Progressive Aphasia. [PDF]

Int J Lang Commun Disord
ABSTRACT Introduction There is a growing evidence base supporting the utility of restitutive speech‐language treatments for individuals with primary progressive aphasia (PPA). In contrast, there is limited research investigating treatment approaches that offer counselling to this population.
Schaffer Mendez K, Evans WS, Dutcher CD, Philburn C, Wauters LD, Young MM, Henry ML.   +6 more
europepmc   +2 more sources

Non-verbal episodic memory deficits in primary progressive aphasias are highly predictive of underlying amyloid pathology [PDF]

, 2016
Diagnostic distinction of primary progressive aphasias (PPA) remains challenging, in particular for the logopenic (lvPPA) and nonfluent/agrammatic (naPPA) variants.
Ahmed, Baddeley, Ballard, Croot, Dubois, Flanagan, Gorno-Tempini, Gorno-Tempini, Gorno-Tempini, Hodges, Irish, Leyton, Machulda, Mioshi, Mioshi, Osterrieth, Piguet, Piguet, Pike, Savage, Schmidt, Wear, Weintraub, Wilson, Wilson   +24 more
core   +1 more source

Primary progressive aphasias: clinical and genetic heterogeneity and diagnostic difficulties

Анналы клинической и экспериментальной неврологии, 2021
This systematic review describes primary progressive aphasia (PPA) variants and includes the authors' own clinical observations. Over 20 genes have now been identified, with mutations that are directly involved in the development of the behavioural ...
Igor V. Litvinenko, Кristina A. Kolmakova, Аndrey Yu. Emelin, Vladimir Yu. Lobzin   +3 more
doaj   +1 more source

Divergent longitudinal propagation of white matter degradation in logopenic and semantic variants of primary progressive aphasia [PDF]

, 2015
Background: Clinico-pathological distinction of primary progressive aphasia (PPA) can be challenging at clinic presentation. In particular, cross-sectional neuroimaging signatures across the logopenic (lvPPA) and semantic (svPPA) variants are difficult ...
Agosta, Bach, Brambati, Chare, Deramecourt, Fletcher, Galantucci, Gorno-Tempini, Gorno-Tempini, Heim, Hickok, Keihaninejad, Lam, Mackenzie, Mahoney, Mesulam, Mesulam, Mioshi, Mioshi, Nichols, Powers, Rohrer, Rohrer, Saur, Savage, Smith, Smith, Smith, Varentsova, Wicklund, Zhang   +30 more
core   +1 more source

The logopenic/phonological variant of primary progressive aphasia [PDF]

Neurology, 2008
Primary progressive aphasia (PPA) is characterized by isolated decline in language functions. Semantic dementia and progressive nonfluent aphasia are accepted PPA variants. A "logopenic" variant (LPA) has also been proposed, but its cognitive and anatomic profile is less defined.
Gorno-Tempini, M L, Brambati, S M, Ginex, V, Ogar, J, Dronkers, N F, Marcone, A, Perani, D, Garibotto, Valentina, Cappa, S F, Miller, B L   +9 more
openaire   +7 more sources

Logopenic and nonfluent variants of primary progressive aphasia are differentiated by acoustic measures of speech production [PDF]

, 2014
Differentiation of logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary Progressive Aphasia is important yet remains challenging since it hinges on expert based evaluation of speech and language production.
A Bechara, A Staiger, Adam P. Vogel, Antoni Rodriguez-Fornells, AP Vogel, AP Vogel, CC Rowe, CE Leyton, Cristian E. Leyton, DB Fry, DS Knopman, E Maas, E-L Low, FH Guenther, G Kochanski, GD Rabinovici, GJ Zyski, HD Critchley, I Aichert, J Duffy, J-P Hosom, JD Rohrer, JD Rohrer, JD Rohrer, JM Ogar, John R. Hodges, JW Bohland, K Croot, K Rosen, KA Josephs, KA Josephs, KA Josephs, Kirrie J. Ballard, KJ Ballard, KJ Ballard, KJ Ballard, KJ Ballard, M Laganaro, M Laganaro, M Mesulam, M Sollberger, M-EA Courson, MA Rogers, MF Folstein, Michael Hornberger, ML Gorno-Tempini, ML Gorno-Tempini, P Boersma, PJ Nestor, R Varley, RD Kent, RD Kent, RM Crum, S Amici, S Ash, S Savage, SA Sajjadi, Sharon Savage, SM Wilson, V Stockmal, V Young, VL Villemagne, W Ziegler, Y Kotani   +63 more
core   +3 more sources

Progranulin-associated PiB-negative logopenic primary progressive aphasia [PDF]

Journal of Neurology, 2014
The logopenic variant of primary progressive aphasia (lvPPA) strongly associates with Alzheimer's disease, but can also associate with frontotemporal lobar degeneration. We aimed to assess the frequency of lvPPA in patients with speech and language disorders without β-amyloid deposition, and to perform detailed neuroimaging and genetic testing in such ...
Keith A, Josephs, Joseph R, Duffy, Edythe A, Strand, Mary M, Machulda, Prashanthi, Vemuri, Matthew L, Senjem, Ralph B, Perkerson, Matthew C, Baker, Val, Lowe, Clifford R, Jack, Rosa, Rademakers, Jennifer L, Whitwell   +11 more
openaire   +2 more sources

White matter disease correlates with lexical retrieval deficits in primary progressive aphasia

Frontiers in Neurology, 2013
Objective: To relate fractional anisotropy changes associated with the semantic and logopenic variants of primary progressive aphasia to measures of lexical retrieval.Methods: We collected neuropsychological testing, volumetric MRI, and diffusion ...
John P. Powers, Corey T. McMillan, Caroline C. Brun, Paul A. Yushkevich, Hui eZhang, James C. Gee, Murray eGrossman   +6 more
doaj   +1 more source