The diagnostic criteria for progressive supranuclear palsy (PSP) incorporate two speech-language disturbances (SLDs), non-fluent/agrammatic primary progressive aphasia and progressive apraxia of speech, but overlook the inclusion of other SLDs, including
Marcelo L. Berthier +15 more
doaj +1 more source
Neologistic jargon aphasia and agraphia in primary progressive aphasia [PDF]
The terms 'jargon aphasia' and 'jargon agraphia' describe the production of incomprehensible language containing frequent phonological, semantic or neologistic errors in speech and writing, respectively.
Rohrer, JD, Rossor, MN, Warren, JD
core
Super‐resolution microscopy identifies nano‐sized tau aggregates (nano‐aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age‐Related Tauopathy, and Alzheimer's disease brains. Morphology and hyperphosphorylation signatures distinguish physiological from pathological forms, with nano ...
Adriana N. Santiago‐Ruiz +5 more
wiley +1 more source
Progressive Apraxia of Speech: Might There Be Subtypes? [PDF]
This study examined speech and language characteristics of three groups of individuals with neurodegenerative disease: (1) primary progressive apraxia of speech (AOS) without aphasia (N=18), (2) agrammatic primary progressive aphasia (agPPA) less severe ...
Duffy, Joseph R. +3 more
core
Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela +12 more
wiley +1 more source
Phonological processing in primary progressive aphasia [PDF]
Primary progressive aphasia (PPA) is a debilitating condition wherein speech and language deteriorate as a result of neurodegenerative disease. Three variants of PPA are now recognized, each of which shows a unique constellation of speech-language ...
Babiak, Miranda +4 more
core
Be concrete to be comprehended:consistent imageability effects in semantic dementia for nouns, verbs, synonyms and associates [PDF]
There are two contrasting views on the nature of comprehension impairment in semantic dementia: (a) that it stems from degradation of a pan-modal " hub" that represents core conceptual knowledge or (b) that it results from degradation of modality ...
Hoffman, Paul +2 more
core +1 more source
Anatomical Progression of Neuropathology in FTLD‐TDP Type C and Linkage to Annexin A11
Objective Frontotemporal lobar degenerations (FTLD)‐TDP type C (TDP‐C) is distinguished from other FTLD‐TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2) phosphorylated TDP‐43 (pTDP) neurites in cortex, and (3) colocalization of all pTDP deposits with annexin A11 (ANXA11).
Allegra Kawles +7 more
wiley +1 more source
Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes. [PDF]
Frontotemporal dementia (FTD), a neurodegenerative disease broadly characterized by socioemotional impairments, includes three clinical subtypes: behavioral variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non-fluent variant ...
Brown, Casey L +7 more
core
Fokus auf der Untersuchung des Einflusses biometrischer Faktoren auf das Ergebnis der nTMS Messung sprachrelevanter Areale neurochirurgischer Patienten [PDF]
Objective: Navigated transcranial magnetic stimulation (nTMS) is a non-invasive mapping tool to locate functional areas of the brain, gaining importance as a preoperative diagnostic device. This is a summary of three studies, Schwarzer et al., Rosenstock
Schwarzer, Vera
core +1 more source

