Results 51 to 60 of about 37,294 (226)

A presumptive association between obsessive compulsions and asymmetric temporal lobe atrophy: a case report

open access: yesJournal of Medical Case Reports, 2022
Background The relatively isolated atrophy of the temporal lobes leads to a clinical radiological pattern, referred to as the temporal variant of frontotemporal dementia.
Thiago Paranhos   +4 more
doaj   +1 more source

Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes. [PDF]

open access: yes, 2019
Frontotemporal dementia (FTD), a neurodegenerative disease broadly characterized by socioemotional impairments, includes three clinical subtypes: behavioral variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non-fluent variant ...
Brown, Casey L   +7 more
core  

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Primary Progressive Aphasia: Variants and Main Language Domains [PDF]

open access: yesАнналы клинической и экспериментальной неврологии
Language is one of the higher brain functions and the primary method of communication, so it plays a key role in human social functioning. Primary progressive aphasia, as a slowly progressive neurodegenerative disease with a clinical predominance of ...
Diliara R. Akhmadullina   +1 more
doaj   +1 more source

Progressive Apraxia of Speech: Might There Be Subtypes? [PDF]

open access: yes, 2013
This study examined speech and language characteristics of three groups of individuals with neurodegenerative disease: (1) primary progressive apraxia of speech (AOS) without aphasia (N=18), (2) agrammatic primary progressive aphasia (agPPA) less severe ...
Duffy, Joseph R.   +3 more
core  

Speech and language therapy for aphasia following stroke [PDF]

open access: yes, 2016
Background  Aphasia is an acquired language impairment following brain damage that affects some or all language modalities: expression and understanding of speech, reading, and writing.
Albert   +306 more
core   +3 more sources

Epilepsy syndromes classification

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell   +4 more
wiley   +1 more source

Case Report: Barely Able to Speak, Can’t Stop Echoing: Echolalic Dynamic Aphasia in Progressive Supranuclear Palsy

open access: yesFrontiers in Aging Neuroscience, 2021
The diagnostic criteria for progressive supranuclear palsy (PSP) incorporate two speech-language disturbances (SLDs), non-fluent/agrammatic primary progressive aphasia and progressive apraxia of speech, but overlook the inclusion of other SLDs, including
Marcelo L. Berthier   +15 more
doaj   +1 more source

Phonological processing in primary progressive aphasia [PDF]

open access: yes, 2013
Primary progressive aphasia (PPA) is a debilitating condition wherein speech and language deteriorate as a result of neurodegenerative disease. Three variants of PPA are now recognized, each of which shows a unique constellation of speech-language ...
Babiak, Miranda   +4 more
core  

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

open access: yesIbrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

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