Results 71 to 80 of about 37,294 (226)

Longitudinal Videofluorographic Dysphagia Measures in Progressive Supranuclear Palsy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dysphagia can lead to fatal aspiration pneumonia in progressive supranuclear palsy (PSP). Little is known about the longitudinal progression of dysphagia or whether it differs across PSP clinical variants. Objectives To characterize longitudinal changes in dysphagia across PSP variants and determine relationships with disease ...
Anna Chiara Cattani, Jerusha G. Bhaskaran, Farwa Ali, Julie Stierwalt, Federica Agosta, Massimo Filippi, Keith A. Josephs, Heather M. Clark, Jennifer L. Whitwell   +8 more
wiley   +1 more source

Primary progressive aphasia: From syndrome to disease

Neurología (English Edition), 2013
Introduction: Primary progressive aphasia (PPA) is a clinical syndrome characterised by a progressive decline in language and speech of neurodegenerative origin.
J.A. Matías-Guiu, R. García-Ramos
doaj   +1 more source

Language impairments in ALS/MND (Amyotrophic Lateral Sclerosis/Motor Neuron Disease) [PDF]

, 2002
Paolo Bongioanni §, Giancarlo Buoiano C§, Marzia Magoni § § Neuroscience Dpt., Univ. Of Pisa, Italy c Corresponding author: Giancarlo Buoiano Via del Morello 8 Bargecchia I-55040 Corsanico (LU) email: giancarlo@neurolinguistics.0catch.com Language ...
Bongioanni, Dr. Paolo, Buoiano, Dr. Giancarlo, Magoni, Dr. Marzia   +2 more
core  

Distinct regional patterns of synaptic vulnerability across hippocampal and parahippocampal subregions in Alzheimer's disease

Brain Pathology, EarlyView.
Synaptic loss in Alzheimer's disease predominantly affects the entorhinal cortex and parahippocampal gyrus. Amyloid‐β and p‐tau pathology show global associations with synaptic density but are limited in specific subregions. Instead, axonal damage associates with synaptic loss locally and in interconnected subregions.
Maud M. A. Bouwman, Irene Frigerio, Yvon Galis‐de Graaf, Wilma D. J. van de Berg, Laura E. Jonkman   +4 more
wiley   +1 more source

The Efficacy of Tele-practice on Expressive Language Outcomes for Adults with Aphasia [PDF]

, 2018
Access to skilled speech and language intervention can be difficult for individuals residing in rural areas as well as for individuals with complex health and mobility issues.
Bailey, Morgan, Burningham, Lauren, Fifield, Erin   +2 more
core   +1 more source

Phonological Processing in Primary Progressive Aphasia [PDF]

Journal of Cognitive Neuroscience, 2016
Abstract Individuals with primary progressive aphasia (PPA) show selective breakdown in regions within the proposed dorsal (articulatory–phonological) and ventral (lexical–semantic) pathways involved in language processing. Phonological STM impairment, which has been attributed to selective damage to dorsal pathway structures, is ...
Maya L. Henry, Stephen M. Wilson, Miranda C. Babiak, Maria Luisa Mandelli, Pélagie M. Beeson, Zachary A. Miller, Maria Luisa Gorno-Tempini   +6 more
openaire   +6 more sources

Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology

Brain Pathology, EarlyView.
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz, Sylwia Tarka, Michał Grzegorczyk, Radosław Rzepliński, Teresa Wierzba‐Bobrowicz, Tomasz Stępień   +5 more
wiley   +1 more source

Clinical Features of Rapidly Progressive Alzheimer's Disease [PDF]

, 2010
Objective: To characterize clinical features, CSF biomarkers and genetic polymorphisms of patients suffering from a rapidly progressing subtype of Alzheimer's dementia (rpAD).
Ahsen, Nico von, Krack, Lennart, Kretzschmar, Hans, Meissner, Bettina, Redyk, Katharina, Roeber, Sigrun, Schmidt, Christian, Zerr, Inga   +7 more
core   +1 more source

Care Needs for Patients Screened Positive for Cognitive Impairment and Delirium: A Cross‐Sectional Observational Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To describe the point prevalence of cognitive impairment in hospitalised adults and evaluate the association with care needs and perceived risks of complications. Design Multi‐site cross‐sectional study on a single day in May 2023. Methods Trained clinician auditors screened adult inpatients in acute medical, surgical, oncology, geriatric,
Alison M. Mudge, Sarah Anderson, Aparna Arjunan, Marguerite Byrnes, Margaret Cahill, Alison Craswell, Joel Dulhunty, Amanda Fox, Nicole C. Gavin, Peter Lawrenson, Karen Lee‐Steere, Hui‐Shan Lin, Andrew Teodorczuk, Elise Treleaven, Laura White, Chloe Yap   +15 more
wiley   +1 more source

The degraded concept representation system in semantic dementia:damage to pan-modal hub, then visual spoke [PDF]

, 2012
The core clinical feature of semantic dementia is a progressive yet selective degradation of conceptual knowledge. Understanding the cognitive and neuroanatomical basis for this deficit is a key challenge for both clinical and basic science.
Acosta-Cabronero, Antonucci, Baayen, Barsalou, Beauchamp, Binder, Binney, Bonner, Bonner, Bozeat, Bozeat, Breedin, Bright, Buxbaum, Capitani, Caramazza, Chao, Coltheart, Farah, Folstein, Funnell, Gainotti, Galantucci, Galton, Garrard, Goldberg, Goll, Gorno-Tempini, Hodges, Hodges, Hoffman, Hoffman, Hoffman, Ishibashi, Jefferies, Jefferies, Jefferies, Kellenbach, Kellenbach, Kiefer, Kiefer, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lewis, Luzzi, Macoir, Marinkovic, Martin, Martin, Matthew A. Lambon Ralph, Mayberry, Mion, Nestor, Papagno, Patterson, Patterson, Paul Hoffman, Pexman, Piwnica-Worms, Plaut, Pobric, Pobric, Pobric, Pulvermuller, Raven, Rogers, Rogers, Rogers, Rohrer, Roy W. Jones, Sharp, Snodgrass, Thompson-Schill, Tyler, Van Dam, Vandenberghe, Visser, Visser, Warrington, Warrington, Warrington, Wechsler, Woollams, Woollams, Yi   +88 more
core   +2 more sources