Results 81 to 90 of about 38,398 (233)

Decision Making Cognition in Primary Progressive Aphasia

Behavioural Neurology, 2012
We sought to investigate the decision making profile of Primary Progressive Aphasia (PPA) by assessing patients diagnosed with this disease (n = 10), patients diagnosed with behavioral variant frontotemporal dementia (bvFTD, n = 35), and matched controls
Ezequiel Gleichgerrcht, Teresa Torralva, María Roca, Daniela Szenkman, Agustin Ibanez, Pablo Richly, Mariángeles Pose, Facundo Manes   +7 more
doaj   +1 more source

Naming treatment in semantic and logopenic variant PPA [PDF]

, 2012
Primary progressive aphasia (PPA) is an acquired impairment of language caused by neurodegenerative disease affecting language regions in the brain. Unlike aphasia caused by stroke, the language impairments in PPA gradually worsen over time as atrophy ...
Gorno-Tempini, Maria Luisa, Henry, Maya L   +1 more
core  

Divergent longitudinal propagation of white matter degradation in logopenic and semantic variants of primary progressive aphasia [PDF]

, 2015
Background: Clinico-pathological distinction of primary progressive aphasia (PPA) can be challenging at clinic presentation. In particular, cross-sectional neuroimaging signatures across the logopenic (lvPPA) and semantic (svPPA) variants are difficult ...
Agosta, Bach, Brambati, Chare, Deramecourt, Fletcher, Galantucci, Gorno-Tempini, Gorno-Tempini, Heim, Hickok, Keihaninejad, Lam, Mackenzie, Mahoney, Mesulam, Mesulam, Mioshi, Mioshi, Nichols, Powers, Rohrer, Rohrer, Saur, Savage, Smith, Smith, Smith, Varentsova, Wicklund, Zhang   +30 more
core   +1 more source

Dendritic location of dystrophic neurites in FTLD‐TDP type C with annexinopathy

Brain Pathology, EarlyView.
The type C variant of FTLD‐TDP (TDP‐C) is defined by long dystrophic neurites that are immunopositive for both phosphorylated TDP and annexin A11 (ANXA11). Kawles et al. are the first paper to systematically show that these neurites are likely of dendritic origin.
Allegra Kawles, Antonia Zouridakis, Caroline Nelson, Rachel Keszycki, Grace Minogue, Alyssa Macomber, Pouya Jamshidi, Rudolph J. Castellani, Changiz Geula, Tamar Gefen, M‐Marsel Mesulam   +10 more
wiley   +1 more source

Case Report: Semantic Variant Primary Progressive Aphasia With Impaired Verbal Word Discrimination [PDF]

, 2022
Nobuko Kawakami, Ayumi Morita, Shigenori Kanno, Nanayo Ogawa, Kazuo Kakinuma, Yumiko Saito, Erena Kobayashi, Wataru Narita, Kyoko Suzuki   +8 more
openalex   +1 more source

The degraded concept representation system in semantic dementia:damage to pan-modal hub, then visual spoke [PDF]

, 2012
The core clinical feature of semantic dementia is a progressive yet selective degradation of conceptual knowledge. Understanding the cognitive and neuroanatomical basis for this deficit is a key challenge for both clinical and basic science.
Acosta-Cabronero, Antonucci, Baayen, Barsalou, Beauchamp, Binder, Binney, Bonner, Bonner, Bozeat, Bozeat, Breedin, Bright, Buxbaum, Capitani, Caramazza, Chao, Coltheart, Farah, Folstein, Funnell, Gainotti, Galantucci, Galton, Garrard, Goldberg, Goll, Gorno-Tempini, Hodges, Hodges, Hoffman, Hoffman, Hoffman, Ishibashi, Jefferies, Jefferies, Jefferies, Kellenbach, Kellenbach, Kiefer, Kiefer, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lewis, Luzzi, Macoir, Marinkovic, Martin, Martin, Matthew A. Lambon Ralph, Mayberry, Mion, Nestor, Papagno, Patterson, Patterson, Paul Hoffman, Pexman, Piwnica-Worms, Plaut, Pobric, Pobric, Pobric, Pulvermuller, Raven, Rogers, Rogers, Rogers, Rohrer, Roy W. Jones, Sharp, Snodgrass, Thompson-Schill, Tyler, Van Dam, Vandenberghe, Visser, Visser, Warrington, Warrington, Warrington, Wechsler, Woollams, Woollams, Yi   +88 more
core   +1 more source

T‐Cell–Redirecting Immunotherapies in Relapsed/Refractory Mantle Cell Lymphoma: Current Evidence, Sequencing, and Future Directions

European Journal of Haematology, EarlyView.
ABSTRACT Relapsed/refractory (R/R) mantle cell lymphoma (MCL) remains a therapeutic challenge, particularly in patients with high‐risk features or prior exposure to Bruton's tyrosine kinase inhibitors (BTKis). The advent of T‐cell–redirecting immunotherapies, including chimeric antigen receptor T‐cell (CAR‐T) therapy and bispecific antibodies (BsAbs ...
Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Progressive compromise of nouns and action verbs in posterior cortical atrophy [PDF]

, 2018
Processing of nouns and action verbs can be differentially compromised following lesions to posterior and anterior/motor brain regions, respectively. However, little is known about how these deficits progress in the course of neurodegeneration.
Borovinsky, Geraldine, Collazo, Lucas, Ferrari, Jesica, García Cordero, Indira Ruth, García, Adolfo Martín, Huizing, Marjolein Catharina, Ibáñez Barassi, Agustín Mariano, Martínez Cuitiño Carricaburo, María Macarena, Sedeño, Lucas, Steeb, Brenda   +9 more
core   +1 more source

Long‐read sequencing of recurrent FGF12 duplications in epilepsy: Insights into structural mechanisms and aberrant isoforms

Epilepsia, EarlyView.
Abstract Objective Fibroblast growth factor 12 (FGF12), a member of the fibroblast homologous factor family, plays a key role in the modulation of voltage‐gated sodium (Nav) channels. Pathogenic variants in the FGF12 gene leading to a gain‐of‐function mechanism and partial duplication encompassing the FGF12 gene leading to a loss‐of‐function mechanism ...
Jade Fauqueux, Laurence Chaton, Pierre Cleuziou, Anne‐Sophie Diependaële, Nathalie Bach, Nicolas Gruchy, Marion Gerard, Jean‐Pascal Meneboo, Céline Villenet, Martin Figeac, Emilie Ait‐Yahya, Caroline Thuillier, Elise Boudry, Adeline Trauffler, Sylvie Nguyen‐The‐Tich, Simon Boussion, Roseline Caumes, Jamal Ghoumid, Thomas Smol   +18 more
wiley   +1 more source

Intravenous magnesium and methocarbamol for acute pain crises in refractory trigeminal neuralgia: A retrospective analysis

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Despite optimized therapy, up to 30% of patients with trigeminal neuralgia (TN) experience treatment failure. To date, there is limited and low‐quality data available on rescue strategies for this subset of patients. This study describes clinical outcomes associated with intravenous (IV) magnesium sulfate and methocarbamol, with or ...
Bradley Ong, Victor Lomachinsky‐Torres, Nymisha Mandava, Harpreet Kaur, Roman Popov, Payal Patel Soni   +5 more
wiley   +1 more source