Charting the course of Sjögren's disease: A historical analysis of scientific progress
Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali +3 more
wiley +1 more source
Primary pulmonary lymphoma: a surgical series. [PDF]
Otero Lozano D +7 more
europepmc +1 more source
Merkel cell carcinoma: an updated guide for pathologists
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley +1 more source
Primary Pulmonary Follicular Lymphoma - a Rare Presentation of Non-Hodgkin Lymphoma
INTRODUCTION Primary pulmonary lymphoma (PPL) is an uncommon form of non-Hodgkin lymphoma that begins in the lungs. PPL originates directly within the lung tissue, unlike more prevalent lymphomas that frequently metastasize to the lungs from other sites.
Parvataneni, Tarun +12 more
core +1 more source
Unveiling the Unseen: A Rare Case of Primary Pulmonary Lymphoma. [PDF]
Jose M, Jayanthi N, P H, P S.
europepmc +1 more source
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin +6 more
wiley +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Primary Thyroid Lymphoma Causing Progressive Respiratory Distress: A Case Report
Primary thyroid lymphoma (PTL) is a rare malignancy of the thyroid gland. It usually presents itself as a very rapidly growing mass, and respiratory distress is commonly the first finding.
İlhan Bali +6 more
core
Retrospective analysis of primary pulmonary lymphoma cases from Polish Lymphoma Research Group centers reveals associations between initial symptoms and outcomes. [PDF]
Giza A +19 more
europepmc +1 more source
MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula +6 more
wiley +1 more source

