Results 101 to 110 of about 609,852 (306)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Clinical study of root canal numbers in maxillary second primary molars
Objective To investigate the root canal numbers of maxillary second primary molars. Methods 216 maxillary second primary molars from 204 children aged 3⁃8 years old were selected. All the teeth need to do the root canal therapy.
JIA Rui⁃zhi +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Armillaria root rot, also known as the honey toadstool or bootlace fungus, is a widespread and often destructive disease that can affect an extremely wide range of plants. Overseas, the disease is reported to be caused by Armillaria mellea. In Australia,
Department of Environment and Primary Industries
core
Arabidopsis root peroxisomes are involved in cadmium responses
Plant peroxisomes are organelles which are known to be involved in the response of plants to different environmental stresses. Despite their simple structure, they are highly versatile in morphology and abundance, and they are the site of an active ROS ...
Maria Maddalena Altamura +5 more
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Immunolocalization is a valuable tool for cell biology research that allows to rapidly determine the localization and expression levels of endogenous proteins.
Barbez, Elkeeditor +5 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Testing for unit roots and the impact of quadratic trends, with an application to relative primary commodity prices [PDF]
In practice a degree of uncertainty will always exist concerning what specification to adopt for the deterministic trend function when running unit root tests.
David I. Harvey +2 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

