Results 101 to 110 of about 396,045 (311)

Number of Teachers in Primary Schools in Latvia, 1919-1939

, 2022
This dataset contains data on number of teachers in primary schools in Latvia in 1919-1939. Dataset "Number of Teachers in Primary Schools in Latvia, 1919-1939" was published implementing project "Historical Sociology of Modern Restorations: a Cross ...
Markevičiūtė, Jurgita, Ambrulevičiūtė, Aelita, Morkevičius, Vaidas, Žvaliauskas, Giedrius, Norkus, Zenonas   +4 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Number of Primary Schools in Latvia, 1919-1939

, 2022
This dataset contains data on number of primary schools in Latvia in 1919-1939. Dataset "Number of Primary Schools in Latvia, 1919-1939" was published implementing project "Historical Sociology of Modern Restorations: a Cross-Time Comparative Study of ...
Markevičiūtė, Jurgita, Ambrulevičiūtė, Aelita, Morkevičius, Vaidas, Žvaliauskas, Giedrius, Norkus, Zenonas   +4 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The separation of lower and higher attaining pupils in the transition from primary to secondary schools: a longitudinal study of London [PDF]

This paper uses methods of spatial analysis to show that lower and higher attaining pupils are separating from each other as they make the transition from primary to secondary schools in London.
Richard Harris
core  

Number of Primary Schools in Lithuania, 1919-1939

, 2022
This dataset contains data on number of primary schools in Lithuania in 1919-1939. Dataset "Number of Primary Schools in Lithuania, 1919-1939" was published implementing project "Historical Sociology of Modern Restorations: a Cross-Time Comparative ...
Markevičiūtė, Jurgita, Ambrulevičiūtė, Aelita, Morkevičius, Vaidas, Žvaliauskas, Giedrius, Norkus, Zenonas   +4 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Accountability of primary schools in the Seychelles : a stakeholder analysis [PDF]

While school accountability continues to gain national prominence in the highly centralised Education System of the Seychelles, concerns have been raised as to how accountable school leaders and teachers are in the primary schools.
Figaro, Veronique
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Number of Pupils in Primary Schools in Lithuania, 1919-1939

, 2022
This dataset contains data on number of pupils in primary schools in Lithuania in 1919-1939. Dataset "Number of Pupils in Primary Schools in Lithuania, 1919-1939" was published implementing project "Historical Sociology of Modern Restorations: a Cross ...
Markevičiūtė, Jurgita, Ambrulevičiūtė, Aelita, Morkevičius, Vaidas, Žvaliauskas, Giedrius, Norkus, Zenonas   +4 more
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source