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Primary Sclerosing Cholangitis [PDF]
Medicine, 1984 Primary sclerosing cholangitis (PSC) is a chronic, cholestatic liver disease caused by diffuse inflammation and fibrosis that can involve the entire biliary tree. The progressive pathological process obliterates intrahepatic and extrahepatic bile ducts, leading ultimately to biliary cirrhosis, portal hypertension and hepatic failure.
Rolland E. Dickson +2 more
+11 more sources
Primary sclerosing cholangitis [PDF]
Radiology, 1971 Summary The literature on the subject of sclerosing cholangitis is reviewed. The value of conserving the gall bladder, of operative cholangiography and of the administration of steroids in the management of these patients is emphasized.
L. F. Tinckler
+11 more sources
Primary sclerosing cholangitis [PDF]
Canadian Journal of Gastroenterology, 2008 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease and reduced life expectancy.
Marina G Silveira, Keith D Lindor
doaj +10 more sources
Primary sclerosing cholangitis [PDF]
Orphanet Journal of Rare Diseases, 2006 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology characterised by inflammation and fibrosis of the biliary tree. The mean age at diagnosis is 40 years and men are affected twice as often as women.
Chapman Roger, Worthington Joy
doaj +9 more sources
Primary Sclerosing Cholangitis
Canadian Journal of Gastroenterology, 2000 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by fibrosing inflammation and obliteration of intra- and/or extrahepatic bile ducts.
A Stiehl, C Benz, P Sauer
doaj +8 more sources
Fine-mapping and molecular characterisation of primary sclerosing cholangitis genetic risk loci [PDF]
Nature CommunicationsGenome-wide association studies of primary sclerosing cholangitis have identified 23 susceptibility loci. The majority of these loci reside in non-coding regions of the genome and are thought to exert their effect by perturbing the regulation of nearby ...
Elizabeth C. Goode +10 more
doaj +2 more sources
Primary Sclerosing Cholangitis
Surgical Clinics of North America, 1990 Primary sclerosing cholangitis is a rare disease of unknown etiology. Sclerosis of the bile ducts may actually be the final result of multiple factors such as autoimmune, bacterial, congenital, drug, or viral injury. The most commonly associated diseases are ulcerative colitis and chronic pancreatitis.
Keith D. Lillemoe +2 more
openalex +4 more sources
IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis
Gut and Liver, 2019 Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes three categories: primary sclerosing cholangitis (PSC), secondary ...
Atsushi Tanaka
doaj +4 more sources
Vancomycin Therapy for Induction and Maintenance of Remission in a Patient with Refractory Ulcerative Colitis and Primary Sclerosing Cholangitis: A Case Report and Literature Review [PDF]
Case Reports in GastroenterologyIntroduction: Ulcerative colitis is a chronic inflammatory bowel disease that affects the colon. About 5% of ulcerative colitis patients also present with primary sclerosing cholangitis, a chronic inflammatory disease marked by cholestasis and
Naama Lang +6 more
doaj +2 more sources
Primary sclerosing cholangitis [PDF]
Abdominal Imaging, 1997 Charles B.L.M. Majoie +2 more
openalex +6 more sources