Results 1 to 10 of about 39,460 (147)

The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease. [PDF]

United European Gastroenterology journal, 2018
BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia.
Bao, X, Brito, H, Moura-Santos, P, Oliveira, A, et al., Palmela, C, Ruiqi, H, Silva, J, Torres, J   +7 more
core   +2 more sources

AASLD Practice Guidance on Primary Sclerosing Cholangitis and Cholangiocarcinoma.

Hepatology, 2022
Pathogenesis of PSC. The current model of the pathogenesis of PSC involves four major themes on a background of underlying genetic and environmental risk factors.
C. Bowlus, L. Arrivé, A. Bergquist, M. Deneau, L. Forman, S. Ilyas, K. Lunsford, Mercedes Martinez, Gonzalo Sapisochin, R. Shroff, J. Tabibian, D. Assis   +11 more
semanticscholar   +1 more source

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: Current Knowledge of Pathogenesis and Therapeutics

Biomedicines, 2022
Cholangiopathies encompass various biliary diseases affecting the biliary epithelium, resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis.
Ji-won Park, Jung-Hee Kim, Sung-Eun Kim, J. Jung, M. Jang, S. Park, Myung‐Seok Lee, H. Kim, K. Suk, D. J. Kim   +9 more
semanticscholar   +1 more source

Impact on follow‐up strategies in patients with primary sclerosing cholangitis

Liver international (Print), 2022
Evidence for the benefit of scheduled imaging for early detection of hepatobiliary malignancies in primary sclerosing cholangitis (PSC) is limited.
A. Bergquist, T. Weismüller, C. Levy, C. Rupp, D. Joshi, J. Nayagam, A. Montaño-Loza, E. Lytvyak, E. Wunsch, P. Milkiewicz, R. Zenouzi, C. Schramm, N. Cazzagon, A. Floreani, Ingalill Friis Liby, M. Wiestler, H. Wedemeyer, Taotao Zhou, C. Strassburg, E. Rigopoulou, G. Dalekos, Manasa Narasimman, X. Verhelst, H. Degroote, M. Vesterhus, A. Kremer, Bennet Bündgens, F. Rorsman, E. Nilsson, K. Jørgensen, Erik von Seth, M. Cornillet, N. Nyhlin, H. Martin, S. Kechagias, K. Wiencke, Mårten Werner, B. Terziroli Beretta‐Piccoli, M. Marzioni, H. Isoniemi, J. Arola, A. Wefer, J. Söderling, M. Färkkilä, H. Lenzen   +44 more
semanticscholar   +1 more source

Secondary sclerosing cholangitis: mimics of primary sclerosing cholangitis

Abdominal Radiology, 2022
Sclerosing cholangitis is a chronic cholestatic disease characterized by stricturing, beading, and obliterative fibrosis of the bile ducts. Sclerosing cholangitis is considered primary (PSC) if no underlying etiology is identified or secondary (SSC) if ...
D. Ludwig, Mark A. Anderson, M. Itani, Kedar G. Sharbidre, N. Lalwani, R. Paspulati   +5 more
semanticscholar   +1 more source

Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis

Pathologica, 2021
Summary Autoimmune cholestatic liver diseases are rare hepato-biliary disorders characterized by a progressive, inflammatory destruction of bile ducts.
S. Sarcognato, D. Sacchi, F. Grillo, N. Cazzagon, L. Fabris, M. Cadamuro, I. Cataldo, C. Covelli, A. Mangia, M. Guido   +9 more
semanticscholar   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

Effects of Primary Sclerosing Cholangitis on Risks of Cancer and Death in People With Inflammatory Bowel Diseases, Based on Sex, Race, and Age.

Gastroenterology, 2020
BACKGROUND & AIMS There are insufficient population-level data on effects of primary sclerosing cholangitis (PSC) in patients with inflammatory bowel disease (IBD). METHODS We identified incident cases of IBD, with PSC (PSC-IBD) and without, from April
P. Trivedi, Hannah Crothers, J. Mytton, S. Bosch, T. Iqbal, J. Ferguson, G. Hirschfield   +6 more
semanticscholar   +1 more source

Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis.

Gastroenterology, 2020
BACKGROUND AND AIMS To influence host and disease phenotype, compositional microbiome changes, which have been demonstrated in patients with primary sclerosing cholangitis (PSC), must be accompanied by functional changes.
M. Kummen, L. Thingholm, M. Rühlemann, K. Holm, S. H. Hansen, L. Moitinho-Silva, T. Liwinski, R. Zenouzi, Christopher Storm-Larsen, Ø. Midttun, A. McCann, P. Ueland, M. Høivik, M. Vesterhus, M. Trøseid, M. Laudes, W. Lieb, T. Karlsen, C. Bang, C. Schramm, A. Franke, J. Hov   +21 more
semanticscholar   +1 more source

Gut microbiome in primary sclerosing cholangitis: A review

World Journal of Gastroenterology, 2020
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by biliary inflammation and stricturing. Exploration of the pathogenesis of PSC in light of its association with inflammatory bowel disease (IBD) and the “gut-liver”
R. Little, E. Wine, B. Kamath, A. Griffiths, A. Ricciuto   +4 more
semanticscholar   +1 more source