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Primary sclerosing cholangitis [PDF]
Canadian Journal of Gastroenterology, 2008 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease and reduced life expectancy.
Marina G Silveira, Keith D Lindor
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Primary sclerosing cholangitis [PDF]
Orphanet Journal of Rare Diseases, 2006 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology characterised by inflammation and fibrosis of the biliary tree. The mean age at diagnosis is 40 years and men are affected twice as often as women.
Chapman Roger, Worthington Joy
doaj +7 more sources
Primary Sclerosing Cholangitis
Nature Reviews Disease PrimersPrimary sclerosing cholangitis (PSC) is a chronic biliary inflammation associated with periductular fibrosis of the intrahepatic and extrahepatic bile ducts leading to strictures, bacterial cholangitis, decompensated liver disease and need for liver transplantation.
Malik S, Dbouk N, Grant LM, Samant H.
europepmc +5 more sources
Primary Sclerosing Cholangitis
Canadian Journal of Gastroenterology, 2000 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by fibrosing inflammation and obliteration of intra- and/or extrahepatic bile ducts.
A Stiehl, C Benz, P Sauer
doaj +6 more sources
IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis
Gut and Liver, 2019 Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes three categories: primary sclerosing cholangitis (PSC), secondary ...
Atsushi Tanaka
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Primary sclerosing cholangitis [PDF]
Translational Gastroenterology and Hepatology, 2021 Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by inflammatory destruction of the intrahepatic and/or extrahepatic bile ducts, leading to bile stasis, fibrosis, and ultimately to cirrhosis, and often requires liver transplantation (LT).
Anahita, Rabiee, Marina G, Silveira
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Risks of colorectal cancer and biliary cancer according to accompanied primary sclerosing cholangitis in Korean patients with ulcerative colitis: a nationwide population-based study [PDF]
Intestinal Research, 2023 Background/Aims We conducted a nationwide population-based study to investigate incidence rates of colorectal and biliary cancers according to accompanying primary sclerosing cholangitis in Korean ulcerative colitis patients.
Eun Hye Oh +5 more
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Primary sclerosing cholangitis
Best Practice & Research Clinical Gastroenterology, 2010 Primary sclerosing cholangitis (PSC) is a chronic bile duct disease leading to fibrotic biliary strictures and liver cirrhosis. The patient population is heterogeneous with regard to disease progression and the presence of co-morbidities, complicating the practical handling of patients as well as studies of pathogenetic mechanisms. The aetiology of PSC
Tom H, Karlsen +2 more
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Primary sclerosing cholangitis with partial steroid responsiveness: a case report
Fujita Medical Journal, 2023 A 69-year-old woman suspected to have IgG4-related sclerosing cholangitis causing bile duct stenosis was transferred from another hospital after diarrhea, eosinophilia, and eosinophilic infiltration were detected and prednisolone was prescribed ...
Satoshi Yamamoto +4 more
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Overlap syndrome of primary biliary cholangitis and primary sclerosing cholangitis: two case reports
Journal of Medical Case Reports, 2023 Background Overlap syndrome between primary biliary cholangitis and primary sclerosing cholangitis is an extremely rare condition that has been reported in only few published cases so far in the literature.
Haythem Yacoub +8 more
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