Results 11 to 20 of about 37,561 (261)

Primary sclerosing cholangitis [PDF]

open access: yesCanadian Journal of Gastroenterology, 2008
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease and reduced life expectancy.
Marina G Silveira, Keith D Lindor
doaj   +5 more sources

Primary sclerosing cholangitis

open access: yesMedicine, 1984
Primary sclerosing cholangitis (PSC) is a chronic, cholestatic liver disease caused by diffuse inflammation and fibrosis that can involve the entire biliary tree. The progressive pathological process obliterates intrahepatic and extrahepatic bile ducts, leading ultimately to biliary cirrhosis, portal hypertension and hepatic failure.
E R, Dickson, N F, LaRusso, R H, Wiesner
exaly   +7 more sources

Primary sclerosing cholangitis [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2006
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology characterised by inflammation and fibrosis of the biliary tree. The mean age at diagnosis is 40 years and men are affected twice as often as women.
Chapman Roger, Worthington Joy
doaj   +7 more sources

Primary Sclerosing Cholangitis

open access: yesCanadian Journal of Gastroenterology, 2000
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by fibrosing inflammation and obliteration of intra- and/or extrahepatic bile ducts.
A Stiehl, C Benz, P Sauer
doaj   +6 more sources

Primary Sclerosing Cholangitis

open access: yesNature Reviews Disease Primers
Primary sclerosing cholangitis (PSC) is a chronic biliary inflammation associated with periductular fibrosis of the intrahepatic and extrahepatic bile ducts leading to strictures, bacterial cholangitis, decompensated liver disease and need for liver transplantation.
Malik S, Dbouk N, Grant LM, Samant H.
europepmc   +7 more sources

IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis

open access: yesGut and Liver, 2019
Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes three categories: primary sclerosing cholangitis (PSC), secondary ...
Atsushi Tanaka
doaj   +4 more sources

Primary sclerosing cholangitis [PDF]

open access: yesTranslational Gastroenterology and Hepatology, 2021
Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by inflammatory destruction of the intrahepatic and/or extrahepatic bile ducts, leading to bile stasis, fibrosis, and ultimately to cirrhosis, and often requires liver transplantation (LT).
Anahita, Rabiee, Marina G, Silveira
openaire   +2 more sources

Primary sclerosing cholangitis

open access: yesBest Practice & Research Clinical Gastroenterology, 2010
Primary sclerosing cholangitis (PSC) is a chronic bile duct disease leading to fibrotic biliary strictures and liver cirrhosis. The patient population is heterogeneous with regard to disease progression and the presence of co-morbidities, complicating the practical handling of patients as well as studies of pathogenetic mechanisms. The aetiology of PSC
Tom H, Karlsen   +2 more
  +7 more sources

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

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