Results 11 to 20 of about 27,193 (247)

IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis

Gut and Liver, 2019
Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes three categories: primary sclerosing cholangitis (PSC), secondary ...
Atsushi Tanaka
doaj   +5 more sources

Primary sclerosing cholangitis [PDF]

Canadian Journal of Gastroenterology, 2008
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease and reduced life expectancy.
Marina G Silveira, Keith D Lindor
doaj   +5 more sources

Primary sclerosing cholangitis

Best Practice & Research Clinical Gastroenterology, 2010
Case History—A 60 yr old woman, known to have long standing colitis, now presenting with abdominal pain and weight loss. Primary sclerosing cholangitis is a chronic cholestatic liver disease caused by diffuse inflammation and fibrosis ...
R.W. Chapman, K.D. Williamson
core   +7 more sources

Primary sclerosing cholangitis [PDF]

Orphanet Journal of Rare Diseases, 2006
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology characterised by inflammation and fibrosis of the biliary tree. The mean age at diagnosis is 40 years and men are affected twice as often as women.
Chapman Roger, Worthington Joy
doaj   +7 more sources

Fine-mapping and molecular characterisation of primary sclerosing cholangitis genetic risk loci

Nature Communications
Genome-wide association studies of primary sclerosing cholangitis have identified 23 susceptibility loci. The majority of these loci reside in non-coding regions of the genome and are thought to exert their effect by perturbing the regulation of nearby ...
Elizabeth C. Goode, Laura Fachal, Nikolaos Panousis, Loukas Moutsianas, Rebecca E. McIntyre, Benjamin Yu Hang Bai, Norihito Kawasaki, Alexandra Wittmann, Tim Raine, Simon M. Rushbrook, Carl A. Anderson   +10 more
doaj   +3 more sources

Primary sclerosing cholangitis

Clinics in Liver Disease, 2013
Primary sclerosing cholangitis is the classic hepatobiliary manifestation of inflammatory bowel disease and is generally chronic and progressive. Patients frequently present with asymptomatic, anicteric cholestasis, but many develop progressive biliary ...
Lindor, Keith D, Hirschfield, Gideon M, Adams, David H, Karlsen, Tom H   +3 more
core   +5 more sources

Primary Sclerosing Cholangitis

Canadian Journal of Gastroenterology, 2000
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by fibrosing inflammation and obliteration of intra- and/or extrahepatic bile ducts.
A Stiehl, C Benz, P Sauer
doaj   +6 more sources

Neonatal cholestasis due to primary sclerosing cholangitis

Journal of Family Medicine and Primary Care, 2016
Neonatal cholestasis is rarely caused due to primary sclerosing cholangitis, which is an inflammatory disease of the bile ducts, which results in obstructive fibrosis of the ducts.
Naman Sadanand Shetty, Ira Shah
doaj   +2 more sources

PREGNANCY WITH PRIMARY SCLEROSING CHOLANGITIS

Акушерство, гинекология и репродукция, 2016
Primary sclerosing cholangitis (PSC) is autoimmune disease characterized by inflammation and sclerosis of the bile duct, which leads to the development of secondary biliary cirrhosis. Many women with primary sclerosing cholangitis are at reproductive age
E. A. Alexandrova, E. Z. Burnevich, E. A. Arion   +2 more
doaj   +1 more source

Primary sclerosing cholangitis

The Lancet, 2018
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis.
Beuers, Ulrich, Jones, David E. J., Dyson, Jessica K., Hudson, Mark, Lohse, Ansgar W.   +4 more
core   +5 more sources