Results 221 to 230 of about 27,193 (247)

Primary sclerosing cholangitis

Current Problems in Surgery, 1992
Primary sclerosing cholangitis is a condition of unknown cause. It is recognized by liver dysfunction and its characteristic radiologic appearance, which is related to portal tract inflammation, bile duct proliferation, and periductal fibroses involving small intrahepatic and large extrahepatic ducts.
F M, Martin, J W, Braasch
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Primary Sclerosing Cholangitis

Inflammatory Bowel Diseases, 2005
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the intra- and extrahepatic bile ducts. An estimated 80% of patients in North America and Europe have coexistent inflammatory bowel disease (IBD). The underlying pathophysiology of PSC remains poorly understood.
Jayant A, Talwalkar, Keith D, Lindor
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Primary Sclerosing Cholangitis

Surgical Clinics of North America, 1981
In spite of an improved understanding of the etiology of primary sclerosing cholangitis, which supports the use of immunosuppressive therapy with steroids and azathioprine, these pharmacologic manipulations have not altered the ultimate outcome of the disease. Drainage remains the most accepted mode of therapy when possible.
L F, Williams, D J, Schoetz
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Primary Sclerosing Cholangitis

Archives of Surgery, 1974
Three patients with primary sclerosing cholangitis confirmed by histologic examination were treated successfully with prolonged (three to six months) common duct drainage. No steroids or antibiotics were used. They are alive 14, 5, and 1½ years postoperatively.
M A, Oviedo, D, Volkmer, E F, Scanlon
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Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

American Journal of Gastroenterology, 2019
Cholestatic liver diseases encompass a broad spectrum of pathologies, with the core injury occurring at the level of cholangiocytes and progressing to hepatic fibrosis and liver dysfunction. Primary biliary cholangitis and primary sclerosing cholangitis are the most significant progressive cholangiopathies in adults. Although rare, they commonly evolve
Raquel T, Yokoda, Elizabeth J, Carey
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Secondary Sclerosing Cholangitis: A Comparison to Primary Sclerosing Cholangitis

The American Journal of Gastroenterology, 2005
The natural history of secondary sclerosing cholangitis (SSC) is ill-defined. In order to better determine the natural history of this condition, we retrospectively reviewed data from the Mayo Clinic in Rochester, Minnesota. We also compared the natural history of patients diagnosed with SSC to a cohort with a diagnosis of primary sclerosing ...
Andrea A, Gossard, Paul, Angulo, Keith D, Lindor   +2 more
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Primary Sclerosing Cholangitis

New England Journal of Medicine, 1995
Y M, Lee, M M, Kaplan
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The microbiota and the gut–liver axis in primary sclerosing cholangitis

Nature Reviews Gastroenterology and Hepatology, 2022
Johannes R Hov, Tom H Karlsen, Hov Johannes R   +2 more
exaly  

A Revised Natural History Model for Primary Sclerosing Cholangitis

Mayo Clinic Proceedings, 2000
W Ray Kim, Terry M Therneau, John J Poterucha   +2 more
exaly   +2 more sources

Genetics of primary sclerosing cholangitis and pathophysiological implications

Nature Reviews Gastroenterology and Hepatology, 2017
Xiaojun Jiang, Tom H Karlsen, Karlsen Tom H   +2 more
exaly