Results 161 to 170 of about 8,351,434 (307)

Tumors affecting primary the sphenoid region - a review of the main lesions

, 2011
Rainer Guilherme Haetinger
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Supratentorial meningeal melanocytoma mimicking meningioma: case report and literature review

Pathology and Oncology Research
Introduction: Primary melanocytic tumors originating from CNS melanocytes are rare, with a low incidence of 0.7 cases per 10 million annually. This study focuses on primary leptomeningeal melanocytomas, emphasizing their epidemiology, clinical ...
Mayle Gomes Ferreira de Araújo, Luiz Euripedes Almondes Santana Lemos, Pedro Lucas Negromonte Guerra, Fernanda Marcia dos Santos Lima Didjurgeit, Auricelio Batista Cezar, Igor Vilela Faquini, Hildo Rocha Cirne de Azevedo Filho   +6 more
doaj   +1 more source

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

Cell, 2018
S. Turajlic, Hang Xu, K. Litchfield, A. Rowan, S. Horswell, T. Chambers, T. O'brien, J. López, T. Watkins, D. Nicol, M. Stares, B. Challacombe, S. Hazell, A. Chandra, T. Mitchell, L. Au, Claudia Eichler-Jonsson, Faiz Jabbar, A. Soultati, S. Chowdhury, S. Rudman, Joanna Lynch, A. Fernando, G. Stamp, E. Nye, A. Stewart, Wei Xing, Jonathan C. Smith, M. Escudero, A. Huffman, Nik Matthews, G. Elgar, B. Phillimore, Marta Costa, Sharmin Begum, S. Ward, M. Salm, S. Boeing, R. Fisher, L. Spain, C. Navas, E. Grönroos, S. Hobor, Sarkhara Sharma, I. Aurangzeb, S. Lall, A. Polson, M. Varia, C. Horsfield, N. Fotiadis, L. Pickering, R. Schwarz, Bruno Silva, Javier Herrero, N. Luscombe, M. Jamal-Hanjani, R. Rosenthal, Nicolai J. Birkbak, G. Wilson, O. Pipek, D. Ribli, M. Krzystanek, I. Csabai, Z. Szallasi, M. Gore, N. Mcgranahan, P. van Loo, P. Campbell, J. Larkin, C. Swanton   +69 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

What Are the Long‐Term Clinical and Functional Outcomes After Hemicortical Allograft Reconstruction for Primary Bone Tumors? [PDF]

Marcos R. Gonzalez, Erhan Okay, Joseph O. Werenski, Joseph J. Connolly, Andrew Pfeiffer, Erik T. Newman, Kevin A. Raskin, Santiago A. Lozano‐Calderón   +7 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Opportunities and Challenges of an Integrative Care Structure for Oncological Patients: A Qualitative Analysis of Provider Perspectives

Health Services Insights
Introduction: Considering the global increase in cancer, integrative medicine combines conventional and complementary methods, offering a holistic approach to treating cancer patients. To optimize care and support care continuity for oncological patients,
Luis Scheck, Jasmin Bossert, Michel Wensing, Nadja Klafke, Regina Poß-Doering   +4 more
doaj   +1 more source

Primary culture of patient tumor cells in multicellular spheroid clusters [PDF]

, 2011

openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source