Results 221 to 230 of about 8,351,434 (307)

Increased 18F-Fluorodeoxyglucose Uptake in a Brown Tumor in a Patient with Primary Hyperparathyroidism [PDF]

, 2007
Kazuhiro Kuwahara, Shoichiro Izawa, Hiroyuki Murabe, Norihiko Murakami, Toshihiko Yokota, Yoji Wani, Kenji Notohara, Choutatsu Tsukayama, Takayoshi Ishimori, Yuji Watanabe   +9 more
openalex   +1 more source

Determination of the most informative prognostic parameters for assessing the status of the epidermal growth factor receptor Her2/neu in the primary tumor in breast cancer patients using the targeted radiopharmaceutical «99mTc-ADAPT6»

, 2021
Olga Bragina, В. И. Чернов, Л. А. Таширева, Roman Zelchan, А. A. Medvedeva, V. Е. Goldberg, Vladimir Tolmachev   +6 more
openalex   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A Rare Nonhepatocytic Primary Liver Neoplasm with an Unusual Presentation: Ossifying Malignant Mixed Epithelial and Stromal Tumor

, 2018
Albina Venus, Sangita Mehta, Sumathi Natarajan   +2 more
openalex   +1 more source

The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase [PDF]

, 2002
Mark Schrader, Angelika M. Burger, Markus Müller, Hans Krause, Bernd F. Straub, Martin Schostak, Wolfgang Schulze, Heidrun Lauke, Kurt Miller   +8 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Abstract 2741: Comprehensive molecular profiling of primary tumors and paired distant metastases in non-small cell lung cancer

, 2019
Won‐Chul Lee, Daniel R. Gomez, Jianhua Zhang, Alexandre Reuben, Ali Jalali, Whijae Roh, Chia-Chin Wu, Wei Lu, Chi-Wan Chow, Junya Fujimoto, Mara B. Antonoff, César A. Moran, Erik P. Sulman, Ganesh Rao, Stephen G. Swisher, John V. Heymach, Ignacio I. Wistuba, P. Andrew Futreal, Jianjun Zhang   +18 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Palliative resection of the primary tumor is associated with improved overall survival in incurable stage IV colorectal cancer: A nationwide population‐based propensity‐score adjusted study in the Netherlands

International Journal of Cancer, 2016
J. 't Lam-Boer, L. G. van der Geest, C. Verhoef, M. Elferink, M. Koopman, J. D. de Wilt   +5 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source