Results 231 to 240 of about 8,351,434 (307)

Relationship of various parameters to recurrence of primary tumors and cervical lymph node metastases in squamous cell carcinomas of the tongue.

, 1994
Katsuya Satoh, Tohru Saito, Ken-ichi NOTANI, Hiroshi Fukuda, Tadashi Iizuka, Masanobu Shindoh, Akira Amemiya, Shigetaka Mizuno   +7 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

EXPERIMENTAL APPROACHES TO DERIVING PRIMARY TUMOR CELL CULTURES FROM CERVICAL CANCER BIOPSIES: A COMPARATIVE ANALYSIS OF PUBLISHED DATA AND OWN EXPERIENCE

, 2017
Olga Kurmyshkina, П. И. Ковчур, Т. О. Волкова   +2 more
openalex   +2 more sources

Platelets surrounding primary tumor cells are related to chemoresistance.

Oncology Report, 2016
S. Ishikawa, T. Miyashita, M. Inokuchi, H. Hayashi, K. Oyama, H. Tajima, Hironori Takamura, I. Ninomiya, A. Karim Ahmed, J. W. Harman, S. Fushida, T. Ohta   +11 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Analyzing the expression of candidate microRNAs in primary tumors of oral squamous cell carcinoma [PDF]

, 2014
Mayakannan Manikandan, Deva Magendhra Rao A K, Arasambattu Kannan Munirajan   +2 more
openalex   +1 more source

Primary tumor location as a prognostic factor in metastatic colorectal cancer.

Journal of the National Cancer Institute, 2015
F. Loupakis, Dongyun Yang, L. Yau, S. Feng, C. Cremolini, Wu Zhang, M. Maus, C. Antoniotti, C. Langer, S. Scherer, T. Müller, H. Hurwitz, L. Saltz, A. Falcone, H. Lenz   +14 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Predictores de detección del tumor primario en pacientes que comienzan con metástasis

Revista Cubana de Medicina
Ricardo Enrique Corrales Rodríguez, Luis Alfonso Senra Armas, Teddy Osmín Tamargo Barbeito   +2 more
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