Results 71 to 80 of about 2,670,118 (351)

Biopsy confirmation of metastatic sites in breast cancer patients:clinical impact and future perspectives [PDF]

, 2014
Determination of hormone receptor (estrogen receptor and progesterone receptor) and human epidermal growth factor receptor 2 status in the primary tumor is clinically relevant to define breast cancer subtypes, clinical outcome,and the choice of therapy ...
A Santinelli, AJ Montero, Alastair M Thompson, AM Thompson, Angela Esposito, Aron Goldhirsch, B Weigelt, BG Mobbs, C Liedtke, C Simmons, C Tapia, CA Gomez-Roca, Carmen Criscitiello, CH Lu, D Gancberg, DS Seah, E Amir, E Amir, E Brogi, EA Mittendorf, EA Perez, EA Perez, EE Lower, EE Lower, F Andre, F André, F Liebens, Fabrice André, Franco Orsi, G Aurilio, G Bogina, G Curigliano, G Viale, Giuseppe Curigliano, HJ Chang, Ida Minchella, J Carlsson, JM Wu, L Ding, L Pusztai, LD Hoefnagel, LM Bender, LS Lindstrom, LS Steelman, Luca Fumagalli, Lucia Gelao, M Scaltriti, Marzia Locatelli, Michele De Laurentiis, MJ Higgins, N Niikura, PJ Stephens, PK Idirisinghe, R Fisher, R Simon, RJ Broom, RJ Leary, S Gupta, S Vignot, SJ Aitken, SM Edgerton, SP Shah, ST Wong, T Forshew, U Wilking, V Guarneri, W Onstenk, Y Gong, Y Nagata, YM Lo   +69 more
core   +5 more sources

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Primary carcinoid tumors of the liver [PDF]

World Journal of Surgical Oncology, 2008
Background: Primary carcinoid tumors of the liver are uncommon and rarely symptomatic. The diagnosis of primary hepatic etiology requires rigorous workup and continued surveillance to exclude a missed primary. Case Presentation: We present a case of a 62-year-old female with a primary hepatic carcinoid tumor successfully resected, now with three years ...
Schwartz, Gary K., Colanta, Agnes, Gaetz, Harold, Olichney, John, Attiyeh, Fadi   +4 more
openaire   +5 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Paired Primary and Recurrent Rhabdoid Meningiomas: Cytogenetic Alterations, BAP1 Gene Expression Profile and Patient Outcome

Biology
Rhabdoid meningiomas (RM) are a rare meningioma subtype with a heterogeneous clinical course which is more frequently associated with recurrence, even among tumors undergoing-complete surgical removal.
Patricia Alejandra Garrido Ruiz, Álvaro Otero Rodriguez, Luis Antonio Corchete, Victoria Zelaya Huerta, Alejandro Pasco Peña, Cristina Caballero Martínez, Joaquín González-Carreró Fojón, Inmaculada Catalina Fernández, Juan Carlos López Duque, Laura Zaldumbide Dueñas, Lorena Mosteiro González, María Aurora Astudillo, Aurelio Hernández-Laín, Emma Natalia Camacho Urkaray, María Amparo Viguri Diaz, Alberto Orfao, María Dolores Tabernero   +16 more
doaj   +1 more source

Risk of invasive breast cancer in relatives of patients with breast carcinoma in situ: a prospective cohort study

BMC Medicine, 2020
Background Wide implementation of mammography screening has resulted in increased numbers of women diagnosed with breast carcinoma in situ. We aimed to determine the risk of invasive breast cancer in relatives of patients with breast carcinoma in situ in
Trasias Mukama, Mahdi Fallah, Hermann Brenner, Xing Xu, Kristina Sundquist, Jan Sundquist, Elham Kharazmi   +6 more
doaj   +1 more source

Primary tumor sidedness and benefit from FOLFOXIRI plus bevacizumab as initial therapy for metastatic colorectal cancer. Retrospective analysis of the TRIBE trial by GONO [PDF]

, 2018
Right-sided metastatic colorectal cancer (mCRC) patients have poor prognosis and achieve limited benefit from first-line doublets plus a targeted agent.
Allegrini, G, Antoniotti, C, Bergamo, F, Boni, L, Buonadonna, A, Cortesi, E, Cremolini, C, Falcone, A, Fontanini, G, Granetto, C, Lonardi, S, Loupakis, F, Marmorino, F, Masi, G, Moretto, R, Racca, P, Ronzoni, M, Sensi, E, Tomasello, G, Tonini, G, Zagonel, V, Zaniboni, A   +21 more
core   +3 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Liver Angiosarcoma with Poor Prognosis in a 61-Year-Old Woman: A Case Report and Literature Review

International Journal of Women's Health, 2022
Tran Manh Hung,1 Thi Phuong Thao Tran2 1Department of Surgery, Bach Mai Hospital, Hanoi, Vietnam; 2Center for Population Health Sciences, Hanoi University of Public Health, Hanoi, VietnamCorrespondence: Tran Manh Hung, Department of Surgery, Bach Mai ...
Manh Hung T, Tran TPT
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source