Results 31 to 40 of about 150,567 (245)

Primate gloom [PDF]

open access: yesCurrent Biology, 2008
SummaryA new worldwide survey finds that almost half of all primate species are in danger of becoming extinct. Nigel Williams reports.
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Historical Demography and Species Distribution Models Shed Light on Speciation in Primates of Northeast India

open access: yesEcology and Evolution
Past climate change is one of the important factors influencing primate speciation. Populations of various species could have risen or declined in response to these climatic fluctuations.
Mihir Trivedi   +7 more
doaj   +1 more source

Analysis of Streptococcus dysgalactiae subspecies equisimilis gene transcripts during experimental primate necrotizing myositis

open access: yesmBio
Streptococcus dysgalactiae subspecies equisimilis (SDSE) is a gram-positive bacterial pathogen capable of causing various infections in humans. Recently, isolates of SDSE emm type stG62647 have emerged as a cause of severe invasive infections, including ...
Jesus M. Eraso   +5 more
doaj   +1 more source

Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov   +2 more
wiley   +1 more source

Pathogenesis and Animal Models of Post-Primary (Bronchogenic) Tuberculosis, A Review

open access: yesPathogens, 2018
Primary and post-primary tuberculosis (TB) are different diseases caused by the same organism. Primary TB produces systemic immunity. Post-primary TB produces cavities to support massive proliferation of organisms for transmission of infection to new ...
Robert L. Hunter   +6 more
doaj   +1 more source

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

open access: yesAdvanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy   +3 more
wiley   +1 more source

Cortisol predicts increased internal capsule integrity in a large sample of non-human primates

open access: yesEuropean Journal of Psychotraumatology, 2012
Background : Cortisol is critical for survival and reflects a primary mechanism by which emotions can influence immune responses throughout the periphery.
Do P.M. Tromp   +6 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Seasonal Adaptation of the Gut Microbiome in Japanese Macaques: Linking Gut Microbiome Shifts With Fermentative Function

open access: yesEcology and Evolution
Seasonal fluctuations in food availability strongly influence the ecology of wild mammals, yet the role of the gut microbiome in mediating these challenges remains insufficiently explored.
Wanyi Lee   +6 more
doaj   +1 more source

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