Results 41 to 50 of about 154,066 (268)

Cortisol predicts increased internal capsule integrity in a large sample of non-human primates

open access: yesEuropean Journal of Psychotraumatology, 2012
Background : Cortisol is critical for survival and reflects a primary mechanism by which emotions can influence immune responses throughout the periphery.
Do P.M. Tromp   +6 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Seasonal Adaptation of the Gut Microbiome in Japanese Macaques: Linking Gut Microbiome Shifts With Fermentative Function

open access: yesEcology and Evolution
Seasonal fluctuations in food availability strongly influence the ecology of wild mammals, yet the role of the gut microbiome in mediating these challenges remains insufficiently explored.
Wanyi Lee   +6 more
doaj   +1 more source

A propos de l'extension complète des doigts longs et des 4 derniers orteils des primates

open access: yesRevue de Primatologie, 2015
L'extenseur commun des doigts des mains et des pieds des Primates agit sur l'aponévrose digitale dorsale, mais ne peut à lui seul en assurer l'extension complète. D'autres muscles, des extenseurs complémentaires, lui viennent en aide.
J Norbert Kuhlmann
doaj   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

CRH receptor genetic variation in a developmental primate model relevant to the risk to develop anxiety and depression

open access: yesEuropean Journal of Psychotraumatology, 2012
Background : Using a well-established non-human primate model of anxious temperament (AT) we characterized alterations in the neural circuit that underlie the dispositional risk to develop anxiety and depression.
Ned H. Kalin   +4 more
doaj   +1 more source

Organes de primates et frontières d’humanité. Les xénogreffes controversées du docteur Voronoff (1910 – 1930)

open access: yesRevue de Primatologie, 2018
The French surgeon Serge Voronoff (1866-1951) made headlines in Paris during the 1920s for his attempt to transplant primate testicles in men. The surgeon was known in Great Britain too.
Catherine Rémy
doaj   +1 more source

Shared and divergent principles of synaptic transmission between cortical excitatory neurons in rodent and human brain

open access: yesFrontiers in Synaptic Neuroscience, 2023
Information transfer between principal neurons in neocortex occurs through (glutamatergic) synaptic transmission. In this focussed review, we provide a detailed overview on the strength of synaptic neurotransmission between pairs of excitatory neurons in
Christiaan P. J. de Kock   +3 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu   +5 more
wiley   +1 more source

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