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Pharmacokinetics of Orally Administered Desferrithiocin Analogs in Cebus apella Primates

Drug Metabolism and Disposition, 1999
The pharmacokinetic behavior of three iron chelators based on the desferrithiocin (DFT) pharmacophore, (S)-4, 5-dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid (desmethyldesferrithiocin, DMDFT, 2); (S)-4,5-dihydro-2-(2, 4-dihydroxyphenyl)-4-thiazolecarboxylic acid [4-(S)-hydroxydesazaDMDFT, 3); and (R)-2-(2-hydroxyphenyl)-4-oxazolinecarboxylic ...
R J, Bergeron, W R, Weimar, J, Wiegand
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Metabolism and pharmacokinetics of N1,N11-diethylnorspermine in a Cebus apella primate model.

Cancer research, 2000
The tissue distribution, metabolic profile, and pharmacokinetic parameters of i.v.-administered N1,N11-diethylnorspermine (DENSPM) are evaluated in Cebus apella primates, and the results are compared with data gathered from canine and human studies.
R J, Bergeron   +6 more
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Satellite DNA sequences in the New World primateCebus apella (Platyrrhini, Primates)

Chromosoma, 1993
Two satellite DNAs, designated CapA and CapB, were isolated from the neotropical primate, Cebus apella. The satellites exhibit nonoverlapping distributions on C. apella chromosomes. CapA is a major component of interstitial regions of constitutive heterochromatin, a very large block of heterochromatin comprising most of the long arm of chromosome 11 ...
T G, Fanning, H N, Seuánez, L, Forman
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Symmetrical gaits of Cebus apella: implications for the functional significance of diagonal sequence gait in primates

Journal of Human Evolution, 2008
Quadrupedal locomotion of primates is distinguished from the quadrupedalism of many other mammals by several features, including a diagonal sequence (DS) footfall used in symmetrical gaits. This presumably unique feature of primate locomotion has been attributed to an ancestral adaptation for cautious arboreal quadrupedalism on thin, flexible branches.
Ian J, Wallace, Brigitte, Demes
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Chemical characterisation of six oligosaccharides in a sample of colostrum of the brown capuchin, Cebus apella (Cebidae: Primates)

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1999
Carbohydrates were extracted from a sample of brown capuchin colostrum and six of the component oligosaccharides were separated and purified by gel filtration and preparative thin layer chromatography. Their structures were determined by 1H-NMR to be as follows: Gal beta 1-->4[Fuc alpha 1-->3]Glc (3-fucosyllactose) Gal beta 1-->3Gal beta 1-->4Glc (beta-
T, Urashima   +8 more
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Electron microscopic study of the origin and formation of Reissner's fiber in the subcommissural organ of Cebus apella (Primates, Platyrrhini)

Cell and Tissue Research, 1980
Two kinds of secretion are formed in cells of the subcommissural organ (SCO) of Cebus apella. The "light secretion" is found in saccules originating from the endoplasmic reticulum. This secretion is stored in the peripheral portion of the cells and is not involved in formation of Reissner's fiber (RF).
H, Hofer, W, Meinel, H, Erhardt
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Urocortin in the central nervous system of a primate (Cebus apella): Sequencing, immunohistochemical, and hybridization histochemical characterization

Journal of Comparative Neurology, 2003
AbstractThe urocortin (UCN)‐like immunoreactivity and UCN mRNA distribution in various regions of the nonprimate mammalian brain have been reported. However, the Edinger‐Westphal nucleus (EW) appears to be the only brain site where UCN expression is conserved across species.
Vasconcelos, LAP   +10 more
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Characterization of constitutive heterochromatin inCebus apella(Cebidae, Primates) andPan troglodytes (Hominidae, Primates): Comparison to human chromosomes

American Journal of Primatology, 1999
Using G bands, some homologies between the chromosomes of Cebus apella (CAP) and human chromosomes are difficult to establish. To solve this problem, we analyzed these homologies by fluorescence in situ hybridization using human whole chromosome probes (ZOO-FISH).
F, García   +4 more
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Nerve growth factor receptor immunoreactivity in the nonhuman primate (Cebus apella): Distribution, morphology, and colocalization with cholinergic enzymes

Journal of Comparative Neurology, 1988
AbstractA monoclonal antibody raised against the receptor for nerve growth factor (NGF) was used to examine the distribution and morphology of NGF receptor‐containing neurons within the central nervous system of Cebus apella monkeys. Most somata demonstrating positive immunoreactivity were localized within the Ch1–4 regions of the basal forebrain ...
J H, Kordower   +4 more
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Grasping primate development: Ontogeny of intrinsic hand and foot proportions in capuchin monkeys (Cebus albifrons and Sapajus apella)

American Journal of Physical Anthropology, 2016
AbstractYoung primates have relatively large hands and feet for their body size, perhaps enhancing grasping ability. We test the hypothesis that selection for improved grasping ability is responsible for these scaling trends by examining the ontogeny of intrinsic hand and foot proportions in capuchin monkeys (Cebus albifrons and Sapajus apella).
Jesse W, Young, Amber N, Heard-Booth
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