Results 91 to 100 of about 578,331 (406)
Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu+15 more
wiley +1 more source
Evolution and Mirror Neurons. An Introduction to the Nature of Self-Consciousness [PDF]
Self-consciousness is a product of evolution. Few people today disagree with the evolutionary history of humans. But the nature of self-consciousness is still to be explained, and the story of evolution has rarely been used as a framework for studies on ...
Menant, Christophe
core
Coalescent-based genome analyses resolve the early branches of the euarchontoglires [PDF]
Despite numerous large-scale phylogenomic studies, certain parts of the mammalian tree are extraordinarily difficult to resolve. We used the coding regions from 19 completely sequenced genomes to study the relationships within the super-clade ...
A Criscuolo+52 more
core +3 more sources
Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang+9 more
wiley +1 more source
We studied the distribution of NADPH-diaphorase activity in the visual cortex of normal adult New World monkeys (Saimiri sciureus) using the malic enzyme "indirect" method. NADPH-diaphorase neuropil activity had a heterogeneous distribution.
J.G. Franca+4 more
doaj +1 more source
Transposable element insertions have strongly affected human evolution [PDF]
Comparison of a full collection of the transposable element (TE) sequences of vertebrates with genome sequences shows that the human genome makes 655 perfect full-length matches.
Britten, Roy J.
core +2 more sources
Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo+4 more
wiley +1 more source
Ladridos y coros de dos especies de monos aulladores, Alouatta coibensis trabeata y Alouatta palliata aequatorialis, fueron analizados para comparar las bandas de frecuencias de sus llamadas.
Pedro G. Méndez-Carvajal
doaj
Of apples and oranges? The evolution of “monogamy” in non-human primates [PDF]
Behavioral ecologists, evolutionary biologists, and anthropologists have been long fascinated by the existence of “monogamy” in the animal kingdom.
Di Fore, Anthony+2 more
core +2 more sources
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source