Results 101 to 110 of about 437,617 (306)
Cell GenomicsSummary: Allele-specific expression (ASE) is pivotal in understanding the genetic underpinnings of phenotypic variation within species, differences in disease susceptibility, and responses to environmental factors.
Ramesh Ramasamy +9 more
doaj +1 more source
Object grasping and manipulation in capuchin monkeys (genera Cebus and Sapajus) [PDF]
, 2018 The abilities to perform skilled hand movements and to manipulate objects dexterously are landmarks in the evolution of primates. The study of how primates use their hands to grasp and manipulate objects in accordance with their needs sheds light on how ...
Carducci, P., Sabbatini, G., Truppa, V.
core +1 more source
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
Advanced Science, EarlyView.. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
Advanced Science, EarlyView.We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source
Vocal communication of White-footed Tamarin (Saguinus leucopus) in the wild
Caldasia, 2013 The white-footed tamarin, Saguinus leucopus, is an endemic primate of Colombia whose vocal communication has been little studied. For a period of a month we applied behavior sampling with continuous record, recording tamarins’ vocalizations, and the ...
Fuentes Jesualdo Arturo +2 more
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Core promoter short tandem repeats as evolutionary switch codes for primate speciation [PDF]
, 2015 Alteration in gene expression levels underlies many of the phenotypic differences across species. Because of their highly mutable nature, proximity to the +1 transcription start site (TSS), and the emerging evidence of functional impact on gene ...
Bagheri, A. +8 more
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Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
Advanced Science, EarlyView.The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Categorization and conceptual behavior in nonhuman primates [PDF]
, 2002 This essay describes some of the studies that have been carried out in the past 5 years with two species of baboons, both in laboratory-controlled conditions (Guinea baboons, Papio papio) and in outdoor settings (olive baboons, Papio anubis)
Vauclair, J
core
Advanced Science, EarlyView.The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source
Acta Biológica ColombianaLa dieta de los monos araña (Ateles spp.) está compuesta en un 90% por frutos maduros. Los monos araña podrían utilizar las cualidades dulce-ácida de las especies de frutos para evaluarlos y aceptarlos por medio del uso del sentido del gusto.
Karol M Gutiérrez Pineda
doaj